[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642014":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":37,"collaborators":26,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":26,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":26,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":67,"whyStopped":26,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":26},{"fullName":5,"class":6},"Shanghai Pulmonary Hospital, Shanghai, China","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Fospropofol Disodium Induction Group","EXPERIMENTAL","Intravenous anesthesia induction using fospropofol disodium combined with sufentanil. Intraoperative anesthetic maintenance, muscle relaxants and postoperative supportive management are identical to the control group",[13],"Drug: Fospropofol disodium plus sufentanil for anesthesia induction",{"label":15,"type":16,"description":17,"interventionNames":18},"Propofol Induction Group","ACTIVE_COMPARATOR","Intravenous anesthesia induction using standard propofol combined with sufentanil. All intraoperative and postoperative auxiliary treatment regimens are consistent with the experimental group to avoid confounding variables.",[19],"Drug: Propofol plus sufentanil for anesthesia induction",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Fospropofol disodium plus sufentanil for anesthesia induction","Intravenous injection of fospropofol disodium combined with sufentanil for anesthesia induction before ureteroscopic surgery. Intraoperative anesthetic maintenance, muscle relaxants and postoperative supportive treatment are consistent with the propofol control group to eliminate intergroup confounding factors.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Propofol plus sufentanil for anesthesia induction","Intravenous injection of conventional propofol combined with sufentanil for anesthesia induction before ureteroscopic surgery. All intraoperative and postoperative auxiliary treatment regimens are identical to the fospropofol disodium experimental group",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Shiyou W Wei","CONTACT","+86 15601680288","lovewishyou@tongji.edu.cn",{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Shiyou Wei","Attending Anesthesiologist","100642014","phase-4-fospropofol-disodium-versus-propofol-for-patient-satisfaction-in-ureteroscopy-100642014",false,"NCT07659132","Fospropofol Disodium Versus Propofol for Patient Satisfaction in Ureteroscopy","Fospropofol Disodium Versus Propofol on Patient Satisfaction in Patients Undergoing Ureteroscopy：A Randomized Controlled Trial","Inclusion Criteria:\n\n* Undergoing elective ureteroscopic surgery\n* Aged between 18 and 90 years old\n* American Society of Anesthesiologists (ASA) physical status classification grade I to III\n\nExclusion Criteria:\n\n* Known allergy to propofol, fospropofol or their excipients\n* Severe cardiopulmonary insufficiency\n* Hepatic and renal dysfunction.Hepatic or renal insufficiency. Hepatic dysfunction: alanine aminotransferase (ALT) \\> 50 U\u002FL, or aspartate aminotransferase (AST) \\> 40 U\u002FL, or total bilirubin (TBIL) ≥ 19 μmol\u002FL; Renal dysfunction: serum creatinine (Cr) \\> 112 μmol\u002FL, or blood urea nitrogen (BUN) \\> 7.1 mmol\u002FL, or receiving dialysis within 28 days before surgery.\n* Pregnancy, lactation, potential pregnancy or planned pregnancy\n* Subjects who refuse to participate","ALL","18 Years","90 Years",{"count":52,"type":53},190,"ESTIMATED","INTERVENTIONAL",[56],"PHASE4","This single-center single-blind randomized trial compares fospropofol disodium and propofol for anesthesia in elective ureteroscopy patients. A total of 190 eligible adults will be randomly divided into two groups at 1:1 ratio with identical intraoperative maintenance protocols. The primary outcome is 24-hour postoperative anesthesia satisfaction assessed by ISAS scale; secondary and safety endpoints include injection pain, intraoperative hemodynamic events and various perioperative adverse reactions. This study explores the clinical efficacy and safety of the two sedatives to guide rational clinical medication.",[59,60],"Anesthesia for Urologic Endoscopic Surgery","Urinary Calculi",[62,63,64,65,66],"fospropofol disodium","propofol","ureteroscopy","anesthesia satisfaction","sedation","NOT_YET_RECRUITING","2026-06-19",{"date":70,"type":71},"2026-06-24","ACTUAL",{"date":73,"type":53},"2026-06-26",{"date":75,"type":53},"2026-09-26",{"name":39,"class":6}]