[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621863":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":27,"responsibleParty":43,"collaborators":20,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":47,"sex":52,"minAge":53,"maxAge":20,"enrollmentInfo":54,"targetDuration":20,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":30,"whyStopped":20,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Instituto de Oftalmología Fundación Conde de Valenciana","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Application of ascorbic acid, hyaluronic acid, and sodium DNA in preparation for their use following","EXPERIMENTAL","Participants will attend a total of four sessions. During the initial session, participants will complete and sign a consent form, baseline photographs will be captured for documentation purposes, and an initial assessment will be conducted using the SASSQ. At the second session, the fractional CO2 laser will be applied, followed by the application of the topical medication to the facial area. During the third and fourth sessions, scheduled one week and four weeks post-treatment, respectively, the facial dermal effects will be objectively evaluated using the SASSQ scale, and any adverse effects will be assessed and documented through photographs.",[13],"Drug: topical hyaluronic acid, ascorbic acid, and sodium DNA following ablative fractional laser treatment",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","topical hyaluronic acid, ascorbic acid, and sodium DNA following ablative fractional laser treatment","The study involves the application of ascorbic acid, hyaluronic acid, and sodium DNA in preparation for their use following the administration of a fractional CO2 laser treatment",[9],null,[22],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Daniel B Mejia Llanes MD, Medical Doctor","CONTACT","+503 6420 5801","db.mejia@outlook.com",[28],{"facility":29,"status":30,"city":31,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Instituto de Oftalmología F.A.P. Conde de Valenciana, I.A.P.","RECRUITING","Mexico City","06800","Mexico","MX",{"type":36,"coordinates":37},"Point",[38,39],-99.12766,19.42847,{"lat":39,"lon":38},[42],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},{"type":44,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100621863","phase-4-fractional-co2-laser-assisted-delivery-of-hyaluronic-acid-ascorbic-acid-and-sodium-dna-for-enhancing-facial-skin-quality-in-individuals-over-the-age-of-30-100621863",false,"NCT07376148","Fractional CO2 Laser-assisted Delivery of Hyaluronic Acid, Ascorbic Acid and Sodium DNA For Enhancing Facial Skin Quality in Individuals Over the Age of 30","FCLADHAAASDFSQ","Inclusion Criteria:\n\n* Male and female subjects, over 30 years of age, with moderate skin changes associated with elasticity, wrinkles, roughness, pigmentation, erythema, and pore size; with at least 12 points on the SASSQ scale. Fitzpatrick skin type I-III. Participants who agree to take part in the protocol\n\nExclusion Criteria:\n\n* Fitzpatrick skin type IV-VI. Local infections or inflammatory disorders.. Neoplasms suspected of being malignant. Allergy to hyaluronic acid, ascorbic acid, and sodium DNA. Hypersensitivity to fractional CO2 laser. Pregnancy or breastfeeding. Local or systemic adverse reaction","ALL","30 Years",{"count":55,"type":56},30,"ESTIMATED","INTERVENTIONAL",[59],"PHASE4","Evaluate the effectiveness of topical hyaluronic acid, ascorbic acid, and sodium DNA following ablative fractional laser treatment in objectively reversing facial skin alterations induced by photoaging.",[62,63,64],"Skin Quality Improvement","Photo-aged Skin","Drug Delivery Systems",[66,67,68],"Skin Quality","Fractional Ablative Resurfacing;","Topical Drugs","2026-01-21",{"date":71,"type":72},"2026-01-29","ACTUAL",{"date":74,"type":72},"2025-11-07",{"date":76,"type":56},"2026-04-30",{"name":5,"class":6},1]