[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610474":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":54,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":25,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":79,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Montefiore Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Single Intramuscular Steroid Injection","ACTIVE_COMPARATOR","Dexamethasone 16mg Intramuscular Single Dose",[13],"Drug: Dexamethasone 16mg IM",{"label":15,"type":10,"description":16,"interventionNames":17},"Oral Steroid Short Course","Prednisone 60mg PO for 5 Days",[18],"Drug: Prednisone 60mg PO",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Dexamethasone 16mg IM","Dexamethasone 16mg Intramuscular Administration Once",[9],null,{"type":21,"name":27,"description":16,"armGroupLabels":28,"otherNames":25},"Prednisone 60mg PO",[15],[30],{"name":31,"affiliation":5,"role":32},"Carlo Lutz, MD","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Mustfa Manzur, MD MPH MS","CONTACT","718-920-6626","mmanzur@montefiore.org",[40],{"facility":5,"status":25,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"The Bronx","New York","10467","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-73.86641,40.84985,{"lat":50,"lon":49},[53],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},{"type":55,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100610474","phase-4-giving-asthmatics-intramuscular-steroids-for-preventing-return-to-the-emergency-department-100610474",false,"NCT07228052","Giving Asthmatics Intramuscular Steroids for Preventing Return to the Emergency Department","Giving Asthmatics Intramuscular Steroids for Preventing Return to the Emergency Department: A Randomized Control Trial","GASPING","Inclusion Criteria:\n\n* Adults ≥18 years old presenting to the ED with an asthma exacerbation\n* Diagnosed with asthma per International Classification of Diseases, 10th Revision (ICD-10) criteria or by the treating clinician\n* Discharged from the ED with a primary diagnosis of asthma exacerbation\n* Initiated systemic corticosteroids during the ED visit\n* Must be English or Spanish speaking\n\nExclusion Criteria:\n\n* Current use of systemic corticosteroids, including Emergency Medical Services (EMS) administration before ED arrival\n* History of severe adverse reactions to corticosteroids\n* Heart failure and uncontrolled diabetes (glucose \\>300mg\u002FdL in the ED)\n* Pregnancy or breastfeeding as prednisone is the preferred treatment for asthma in this population\n* Inability to provide informed consent","ALL","18 Years",{"count":67,"type":68},182,"ESTIMATED","INTERVENTIONAL",[71],"PHASE4","This study aims to compare the efficacy of a one-time IM dose of dexamethasone versus a 5-day course of prednisone in adult ED patients presenting with asthma exacerbations. This is a randomized, controlled, double-blind, non-inferiority trial conducted at two urban EDs within the Montefiore Health System.",[74],"Asthma",[76,77,78],"dexamethasone","prednisone","randomized controlled trial","NOT_YET_RECRUITING","2026-06-22",{"date":82,"type":83},"2026-06-24","ACTUAL",{"date":85,"type":68},"2026-07",{"date":87,"type":68},"2026-12",{"name":5,"class":6},1]