[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629801":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":31,"centralContacts":32,"locations":31,"responsibleParty":38,"collaborators":31,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":31,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":31,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":66,"whyStopped":31,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":31},{"fullName":5,"class":6},"Hasanuddin University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control arm of the intervention study","PLACEBO_COMPARATOR","This is the control arm of the intervention study. Subjects will be administered dextrin alone (placebo)",[13],"Dietary Supplement: Placebo (dextrin)",{"label":15,"type":6,"description":16,"interventionNames":17},"Active arm of the intervention study","This is the active arm of the intervention study.Subjects will be administered dextrin including AHCC.",[18],"Dietary Supplement: a prebiotic, that us a standardized extract of cultured Lentinula edodes mycelia",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","a prebiotic, that us a standardized extract of cultured Lentinula edodes mycelia","Subjects will be administered dextrin including AHCC.",[15],[26],"AHCC",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Placebo (dextrin)","Subjects will be administered dextrin alone (placebo)",[9],null,[33],{"name":34,"role":35,"phone":36,"phoneExt":31,"email":37},"Conny Tanjung, PhD; Consultant Pediatrician","CONTACT","+6281282733388","conny.tanj@gmail.com",{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Conny Tanjung","Principal Investigator","100629801","phase-4-impact-of-ahcc-supplementation-for-prevention-of-respiratory-tract-infections-among-children-age-2-4-years-old-100629801",false,"NCT07479394","Impact of AHCC® Supplementation for Prevention of Respiratory Tract Infections Among Children Age 2-4 Years Old","A Double-Blind, Randomized, Placebo-Controlled Trial of AHCC® Supplementation for Prevention of Respiratory Tract Infections Among Children Age 2-4 Years Old","Inclusion Criteria:\n\n1. Children aged 2-4 years old at the time of enrolment\n2. Good nutritional status with weight-for-height \\> -2, and height-for-age z-score \\> -2 based on WHO growth standards\n3. Infants in a group setting (daycare centers).\n4. No congenital disorder\n5. Not suffering from severe coughing or diarrhoea at the time of recruitment\n6. Written informed consent will be obtained from parents or legal guardians before enrollment.\n\nExclusion Criteria:\n\n* Presence of chronic illnesses or conditions (congenital disorder, genetic syndromes, congenital heart disease, chronic renal failure, cystic fibrosis, etc)\n* Children who have participated in another clinical intervention study within the past 30 days.\n* Children who are likely to be transferred to another facility that is not part of the study before completing the follow-up period",true,"ALL","2 Years","4 Years",{"count":54,"type":55},60,"ESTIMATED","INTERVENTIONAL",[58],"PHASE4","This is a study to evaluate the effects of a prebiotic, AHCC, a standardized extract of cultured Lentinula edodes mycelia, on immunologic markers and the incidence of respiratory tract infections in children.",[61],"Respiratory Tract Infections (RTI)",[26,63,64,65],"Lentinula edodes mycelia","prebiotic","respiratory tract infection (RTI)","NOT_YET_RECRUITING","2026-03-16",{"date":69,"type":70},"2026-03-18","ACTUAL",{"date":72,"type":55},"2026-06-01",{"date":74,"type":55},"2026-12-31",{"name":5,"class":6}]