[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573944":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":25,"locations":31,"responsibleParty":48,"collaborators":24,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":24,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":24,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":34,"whyStopped":24,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients undergoing ear, nose and throat surgeries who will receive dexmedetomidine infusion","ACTIVE_COMPARATOR","Dexmedetomidine group: the patients will receive deliberate hypotensive anesthesia with dexmedetomidine infusion (precedex ® 200 μg\u002F2 ml; Hospira, Inc., Rocky Mount, USA) via syringe pump by adding 200 mcg (2ml) of dexmedetomidine to 48 ml of normal saline (final concentration of 4 mcg\u002Fml) The patients will receive a loading dose of 1mcg\u002Fkg intravenously followed by an infusion of 0.7 mcg\u002Fkg\u002Fhour as maintenance dose.",[13],"Drug: Hypotensive anesthesia in ear, nose and throat surgeries using labetalol and dexmedetomidine infusions",{"label":15,"type":10,"description":16,"interventionNames":17},"Patients undergoing ear, nose and throat surgeries who will receive Labetalol infusion","Labetalol groups: the patients will receive deliberate hypotensive anesthesia with labetalol infusion (Labipress 100mg\u002F20ml; Al Debeiky pharma(DBK) pharmaceutical co., Cairo, Egypt) via syringe pump by adding 100 mg (20ml) of Labetalol to 30ml of normal saline (final concentration of 2 mg\u002Fml) The patients will receive a loading dose of 0.4mg\u002Fkg intravenously followed by an infusion of 0.04mg\u002Fkg\u002Fhour as maintenance dose.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","Hypotensive anesthesia in ear, nose and throat surgeries using labetalol and dexmedetomidine infusions","The study compares the role of Labetalol infusion versus Dexmedetomidine infusion in hypotensive anesthesia in patients having ear, nose and throat surgeries",[15,9],null,[26],{"name":27,"role":28,"phone":29,"phoneExt":24,"email":30},"Nourhan Osama, Master degree","CONTACT","002 01064764758","NourhanosamaMohamed@med.asu.edu.eg",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Ain Shams university","RECRUITING","Cairo","Cairo Governorate","11517","Egypt","EG",{"type":41,"coordinates":42},"Point",[43,44],31.24967,30.06263,{"lat":44,"lon":43},[47],{"name":27,"role":28,"phone":24,"phoneExt":24,"email":24},{"type":49,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100573944","phase-4-labetalol-infusion-and-dexmedetomidine-infusion-in-hypotensive-anesthesia-100573944",false,"NCT06752863","Labetalol Infusion and Dexmedetomidine Infusion in Hypotensive Anesthesia","Comparative Study of Labetalol Infusion Versus Dexmedetomidine Infusion in Hypotensive Anesthesia in Ear, Nose and Throat Surgeries","Inclusion Criteria:\n\n* American Society of Anesthesiologists I, II (ASA I, II) patients who were candidate for Ear, Nose and Throat surgeries.\n* Age: between 20 and 50 years\n\nExclusion Criteria:\n\n* Patients with uncontrolled hypertension, variable degrees of heart block, congestive cardiac failure, coagulopathy, cerebral insufficiency, hepatic or renal abnormality\n* Patients on beta blocker or clonidine\n* Pregnant or lactating females\n* Patients who were allergic to any of the anesthetic or hypotensive drugs used in the study\n* Patient refusal to be included in the trial","ALL","20 Years","50 Years",{"count":61,"type":62},80,"ESTIMATED","INTERVENTIONAL",[65],"PHASE4","this study aims to compare between the role of Labetalol infusion versus Dexmedetomidine infusion in hypotensive anesthesia in Ear, Nose and Throat surgeries.",[68,69],"Hypotensive Anesthesia","Ear, Nose and Throat Procedure",[71,72,73],"Hypotensive anesthesia","Labetalol","Dexmedetomidine","2024-12-21",{"date":76,"type":77},"2024-12-31","ACTUAL",{"date":79,"type":77},"2024-11-27",{"date":81,"type":62},"2025-12",{"name":5,"class":6},1]