[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602486":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":63,"collaborators":66,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":25,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":25,"enrollmentInfo":78,"targetDuration":25,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Eastern Virginia Medical School","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"5% dextrose and Lactate Ringer","ACTIVE_COMPARATOR","Participants randomized to this arm will receive an intravenous solution of 5% dextrose and Lactate Ringer during labor.",[13,14],"Drug: 5% Dextrose (D5) in Normal Saline (NS)","Drug: Lactate Ringer",{"label":16,"type":10,"description":17,"interventionNames":18},"Lactate Ringer only","Participants randomized to this arm will receive an intravenous Lactate Ringer solution only.",[14],[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","5% Dextrose (D5) in Normal Saline (NS)","A solution of 5% dextrose and lactate ringer will be given to one group of participants.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Lactate Ringer","A Lactate Ringer solution will be given to one group of participants.",[9,16],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Tetsuya Kawakita, MD","CONTACT","757-446-7900","kawakit@odu.edu",[37,53],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Sentara Norfolk General Hospital","RECRUITING","Norfolk","Virginia","23507","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-76.28522,36.84681,{"lat":49,"lon":48},[52],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"facility":54,"status":39,"city":55,"state":25,"zip":25,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":62,"contacts":25},"Policlinico di Modena","Modena","Italy","IT",{"type":46,"coordinates":59},[60,61],10.92539,44.64783,{"lat":61,"lon":60},{"type":64,"investigatorFullName":32,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Associate Professor",[67],{"name":68,"class":6},"University of Modena and Reggio Emilia","100602486","phase-4-lactated-ringers-and-dextrose-5-vs-only-lactated-ringers-in-labor-100602486",false,"NCT07124130","Lactated Ringer's and Dextrose 5% vs Only Lactated Ringer's in Labor","Parenteral Lactated Ringer's Plus Dextrose 5% vs Lactated Ringer's in Labor: A Randomized Control Trial on Maternal and Neonatal Outcomes","Inclusion Criteria:\n\n* Nulliparous women\n* Age 18 years or older and able to provide informed consent\n* Singleton pregnancy at term\n* Induction of labor\n* Cephalic presentation\n* Unfavorable cervix (Bishop score ≤ 6)\n\nExclusion Criteria:\n\n* Age under 18 years\n* Involuntarily confined or detained\n* Considered as having diminished decision-making capacity\n* Spontaneous labor (cervical exam between 5-6 cm) with or without ruptured membraned\n* Favorable cervix (Bishop score \\>6)\n* Diabetes mellitus (both gestational and pre-gestational)\n* Structural renal disease\n* Acute or chronic kidney disease resulting in abnormal creatinine or proteinuria\n* Evidence of chorioamnionitis or non-reassuring fetal testing at the time of enrollment\n* Pyrexia (\\>38.0 degrees Celsius)\n* Stillbirth\n* Planned cesarean delivery\n* Women presenting with emergent circumstances for labor induction","FEMALE","18 Years",{"count":79,"type":80},158,"ESTIMATED","INTERVENTIONAL",[83],"PHASE4","The goal of this clinical trial is to determine which of two types of standard intravenous (IV) fluids (a combination of 5% dextrose and Lactated Ringers solution and Lactated Ringers solution alone) has a better influence on labor when inducing labor in pregnant women. The main questions it aims to answer are:\n\n1. Does the use of 5% dextrose and Lactated Ringers lead to a shorter labor than the use of just Lactated Ringers?\n2. Does the use of 5% dextrose and Lactated Ringers increase the risk of neonatal hypoglycemia when compared to Lactated Ringers? Participants in this trial will be randomly assigned to one of two groups: a group that receives a solution of 5% dextrose and Lactated Ringers, and a group that receives Lactated Ringers alone. Researchers will compare the outcomes of the two groups to see which IV fluid is more effective.",[86],"Induced Labor",[88,89,90,91],"Induced labor","5% dextrose","Lactated Ringers","duration of labor","2025-08-18",{"date":94,"type":95},"2025-08-22","ACTUAL",{"date":97,"type":80},"2025-09",{"date":99,"type":80},"2026-03",{"name":5,"class":6},2]