[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100521105":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":38,"centralContacts":43,"locations":50,"responsibleParty":64,"collaborators":48,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":48,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":48,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":88,"whyStopped":48,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Damascus Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"sequential","EXPERIMENTAL","Measure eradication rate of Helicobacter pylori infection with Levofloxacien sequential based regimen",[13],"Drug: sequential",{"label":15,"type":16,"description":17,"interventionNames":18},"concomitant","ACTIVE_COMPARATOR","Measure eradication rate of Helicobacter pylori infection with Livofloxacine concomitant based regimen",[19],"Drug: Levofloxacin 500Mg Oral Tablet",[21,30],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","amoxicillin 1000 mg bid ,esomprazole 20 bid for one week then levofloxacine 500 mg q.d, metraonidazoel 500 500 bid, and esomprazole 20 bid for one week",[9],[26,27,28,29],"Esomeprazole","levofloxacine","metronidazole","amoxicillin",{"type":22,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Levofloxacin 500Mg Oral Tablet","Levofloxacin 500 mg qd, amoxicillin 500 2cab bid,Tinadizole 500 bid, esomprazole 20 bid",[15],[35,36,37],"Amoxicilline","Esomeprazol","Tinadizole",[39],{"name":40,"affiliation":41,"role":42},"Marouf M Alhalabi, MD","general assambly of damascus hospital","PRINCIPAL_INVESTIGATOR",[44],{"name":45,"role":46,"phone":47,"phoneExt":48,"email":49},"Marouf MH Alhalabi, MD","CONTACT","+963952781278",null,"e.marouf@hotmail.com",[51],{"facility":52,"status":48,"city":53,"state":48,"zip":48,"country":54,"countryCode":48,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"General Assembly of Damascus Hospital","Damascus","Syria",{"type":56,"coordinates":57},"Point",[58,59],36.29128,33.5102,{"lat":59,"lon":58},[62],{"name":63,"role":46,"phone":47,"phoneExt":48,"email":49},"Marouf MI Alhalabi, MD",{"type":42,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":48,"oldOrganization":48},"Marouf Alhalabi","head of digestive diseases department","100521105","phase-4-levofloxacin-concomitant-versus-levofloxacin-sequential-100521105",false,"NCT06065267","Levofloxacin Concomitant Versus Levofloxacin Sequential","Efficacy of Two-week Therapy With Levofloxacin-based Concomitant Regimen Versus Levofloxacin-based Sequential Regimen for Helicobacter Pylori Infection in Syrian Population: a Prospective Single-center Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients are aged greater than 18 years old who have H. pylori infection diagnosed by any of following three methods:\n* Positive rapid urease test (CLOtest).\n* Histologic evidence of H. pylori by modified Giemsa staining.\n* Positive 13C-urea breath test. without prior eradication therapy and are willing to receive therapy.\n\nExclusion Criteria:\n\n* Children and teenagers aged less than 18 years.\n* Previous eradication treatment for H. pylori.\n* Patients who took any drug, which could influence the study results such as proton pump inhibitor, H2 blocker, mucosal protective agent and antibiotics.\n* History of gastrectomy.\n* Gastric malignancy, including adenocarcinoma and lymphoma,\n* Previous allergic reaction to antibiotics (Amoxicillin, Tinadizole,\n* Doxycycline,Bismuth subsalicylate,) and prompt pump inhibitors (Es- omeprazole).\n* Contraindication to treatment drugs.\n* Pregnant or lactating women.\n* Severe concurrent disease.\n* Liver cirrhosis.","ALL","18 Years","80 Years",{"count":78,"type":79},150,"ESTIMATED","INTERVENTIONAL",[82],"PHASE4","The goal of this trial is to determine the efficacy of levofloxacin based sequential treatment regimen or concomitant levofloxacin based regimens as empirical first-line therapy in the Syrian population",[85],"Helicobacter Pylori Infection",[87,27,15,9],"Helicobacter Pylori","NOT_YET_RECRUITING","2023-09-27",{"date":91,"type":92},"2023-10-03","ACTUAL",{"date":94,"type":79},"2024-01-02",{"date":96,"type":79},"2027-06-30",{"name":5,"class":6},1]