[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629333":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":31,"locations":37,"responsibleParty":52,"collaborators":25,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":25,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":25,"enrollmentInfo":63,"targetDuration":25,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":40,"whyStopped":25,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Mansoura University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"LiSWT group","EXPERIMENTAL","Allocated to receive LiSWT",[13],"Other: Low intensity shockwave therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Solifenacin Group","ACTIVE_COMPARATOR","Allocated to receive oral Solifenacin succinate 5 mg",[19],"Drug: Oral Solifenacin succinate 5 mg",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Low intensity shockwave therapy","Participants will receive Li-SWT which will be applied once weekly for 8 weeks, with a focused shockwave. The bladder will be scanned by US to ensure that t is filled with approximately 50% of the maximum cytometric capacity as measure by baseline cystometry. The patients will be asked to lie flat in a supine position. The device will be operated by a well-trained urologist. A commercially used gel for sonography will be applied to suprapubic region. The applicator will be applied to the S.P region in 3 horizontal sites. 2 cm from each other and 2 fingerbreadths above the pubic bone with 45° tilt.\n\nLi-SWT will be applied with energy density of 0.12 mJ\u002Fmm² and frequency of 4 pulses\u002Fsecond for a total of 3000 pulses per session (1000 pulses per bladder dome and each lateral wall at 45° tilt).",[9],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"DRUG","Oral Solifenacin succinate 5 mg","Participants will receive solifenacin succinate 5 orally once daily for 12 months",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":25,"email":36},"Yahya H Elmorsy","CONTACT","00201100311999","Hossam.Yahya@yahoo.com",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":25},"Mansoura Faculty of medicine","RECRUITING","Al Mansurah","Dakahlia Governorate","35111","Egypt","EG",{"type":47,"coordinates":48},"Point",[49,50],31.38069,31.03637,{"lat":50,"lon":49},{"type":53,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100629333","phase-4-low-intensity-shockwave-therapy-versus-solifenacin-for-the-treatment-of-overactive-bladder-in-women-100629333",false,"NCT07473310","Low-intensity Shockwave Therapy Versus Solifenacin for the Treatment of Overactive Bladder in Women","Low-intensity Shockwave Therapy Versus Solifenacin for the Treatment of Overactive Bladder in Women: A Randomized Controlled Trial","Inclusion Criteria:\n\n* OAB symptoms persisting for ≥3 months.\n* OAB Symptom Score (OABSS) ≥7.\n* Ability and willingness to provide informed consent\n\nExclusion Criteria:\n\n* Active urinary tract infection.\n* Stress urinary incontinence as primary diagnosis.\n* Pelvic organ prolapse stage ≥II.\n* History of pelvic radiation or surgery within 6 months.\n* Use of anticholinergics or β3-agonists for the past 4 weeks who are unwilling to undergo washout.\n* Pregnancy or breast feeding.\n* Neuropathic diseases or psychological disorders.\n* History of urogenital malignancy.\n* Uncontrolled DM (HbA1c \\> 6.8)\n* Uncorrected coagulopathy or severe cardiovascular disease.\n* Contraindication to solifenacin e.g.: closed angle glaucoma)","FEMALE","18 Years",{"count":64,"type":65},70,"ESTIMATED","INTERVENTIONAL",[68],"PHASE4","The goal of this clinical trial is to evaluate the effectiveness and safety of low-intensity shockwave therapy (Li-SWT) for the treatment of overactive bladder (OAB) in adult women.\n\nThe main questions this study aims to answer are whether Li-SWT improves overactive bladder symptoms and quality of life, and whether these improvements are sustained over a 12-month follow-up period, compared with standard medical therapy.\n\nResearchers will compare Li-SWT with oral solifenacin succinate, a commonly used antimuscarinic medication for OAB.\n\nParticipants will be randomly assigned to receive either Li-SWT once weekly for 8 weeks or solifenacin 5 mg taken orally once daily for 12 months. All participants will complete symptom questionnaires and three-day voiding diaries and will undergo uroflowmetry, post-void residual measurement, and filling cystometry at specified time points during follow-up.",[71,72],"Overactive Bladder (OAB)","Urge Incontinence",[74,75,76,77],"OAB","overactive bladder","low intensity shockwave","solifenacin","2026-03-10",{"date":80,"type":81},"2026-03-16","ACTUAL",{"date":83,"type":81},"2025-11-11",{"date":85,"type":65},"2027-12",{"name":5,"class":6},1]