[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100445448":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":38,"locations":44,"responsibleParty":61,"collaborators":32,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":66,"sex":72,"minAge":73,"maxAge":32,"enrollmentInfo":74,"targetDuration":32,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":86,"overallStatus":46,"whyStopped":32,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"UMC Utrecht","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MOH\u002FIUI treatment with LPS","EXPERIMENTAL","(Mild) Ovarian stimulating treatment and insemination are according to regular treatment protocol. Females assigned to the treatment group start LPS, applying 3dd200mg Utrogestan in vaginal capsules, on the day of IUI. Treatment is continued until the onset of menstruation, a negative pregnancy test, miscarriage or confirmed vital intra-uterine pregnancy at 7 weeks gestation",[13],"Drug: Progesterone Vaginal Product",{"label":15,"type":16,"description":17,"interventionNames":18},"MOH\u002FIUI treatment with placebo","PLACEBO_COMPARATOR","Females will receive regular MOH\u002FIUI treatment. The female cycle is mildly stimulated and monitored until the desired amount of ripe follicles is achieved. In the absence of other reasons to cancel the treatment, ovulation is triggered and subsequently pre-washed semen is inseminated into the uterus.\n\nFemales assigned to the placebo group start placebo, applying 3dd1 vaginal capsules, on the day of IUI. Treatment is continued until the onset of menstruation, a negative pregnancy test, miscarriage or confirmed vital intra-uterine pregnancy at 7 weeks gestation",[19],"Drug: Placebo",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Progesterone Vaginal Product","3dd200mg",[9],[27],"Utrogestan",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Placebo","3dd1 vaginal capsule",[15],null,[34],{"name":35,"affiliation":36,"role":37},"Broekmans, Prof. Dr.","Professor Reproductive Medicine","PRINCIPAL_INVESTIGATOR",[39],{"name":40,"role":41,"phone":42,"phoneExt":32,"email":43},"Simone Broer, Dr.","CONTACT","088 755 75 25","s.l.broer-2@umcutrecht.nl",[45],{"facility":5,"status":46,"city":47,"state":32,"zip":32,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"RECRUITING","Utrecht","Netherlands","NL",{"type":51,"coordinates":52},"Point",[53,54],5.12222,52.09083,{"lat":54,"lon":53},[57,59],{"name":58,"role":41,"phone":42,"phoneExt":32,"email":43},"Simone Broer",{"name":60,"role":41,"phone":32,"phoneExt":32,"email":32},"Broer",{"type":37,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Frank JM Broekmans","Professor in Reproductive Endocrinology & Surgery","100445448","phase-4-luteal-phase-support-in-iui-moh-treatment-luteal-phase-support-in-iui-moh-treatment-100445448",false,"NCT05080569","Luteal Phase Support in IUI MOH Treatment Luteal Phase Support in IUI MOH Treatment","LUMO Study: Luteal Phase Support in IUI MOH Treatment Luteal Phase Support in IUI MOH","LUMO","Inclusion Criteria:\n\n* Couples starting IUI with Mild Ovarian HyperStimulation (MOH), with the intend to receive this treatment for at least six months.\n* Diagnosis of unexplained (primary or secondary) infertility\n* Hunault \\\u003C30% (or \\>30%, after an expectant management period of at least 6 additional months).\n* Females aged \\>18 years with regular menstrual cycle.\n* Total mobile sperm count (VCM) \\>10 million.\n\nExclusion cirteria:\n\n* Cycle irregularities\n* Male factor infertility","FEMALE","18 Years",{"count":75,"type":76},1008,"ESTIMATED","INTERVENTIONAL",[79],"PHASE4","The LUMO study is a multicenter, randomized controlled trial that evaluates the effectivity of luteal phase support in MOH\u002FIUI treatment.",[82,83,84,85],"Pregnancy Related","Fertility Issues","Luteal Phase Defect","Infertility Unexplained",[87,88,89,90,91,92,93,94],"progesterone","Cost-effective","Intrauterine insemination","live birth","luteal support","ongoing pregnancy","ovulation induction","unexplained infertility","2025-12-23",{"date":97,"type":98},"2025-12-31","ACTUAL",{"date":100,"type":98},"2023-03-01",{"date":102,"type":76},"2027-07",{"name":5,"class":6},1]