[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596344":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":35,"locations":44,"responsibleParty":61,"collaborators":34,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":66,"sex":72,"minAge":73,"maxAge":34,"enrollmentInfo":74,"targetDuration":34,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":46,"whyStopped":34,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Aarhus University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Nicardipine infusion based acute blood pressure lowering treatment","EXPERIMENTAL","1. Nicardipine : Infusion at 5 mg\u002Fhour ( 2.5 mg\u002Fhour in renal or hepatic impairment and elderly. Taper after 4-6 hours.\n2. Labetalole: Dose: 10-20 mg IV, repeat as needed.\n3. Methyldopa: Dose: 250 mg three times daily (max 500 mg four times daily) orally or via feeding tube\n\nAcute antihypertensive treatment duration \\\u003C72 hours",[13],"Combination Product: Nicardipine",{"label":15,"type":16,"description":17,"interventionNames":18},"Glyceryl trinitrate patchbased acute blood pressure lowering treatment","ACTIVE_COMPARATOR","1. Glyceryltrinitrate : Patch 5 or 10mg\u002F24hour.\n2. Labetalole: Dose: 10-20 mg IV, repeat as needed.\n3. Nimotope: Dose: 30 or 60mg x 6 orally or via feeding tube\n\nAcute antihypertensive treatment duration \\\u003C72 hours",[19],"Combination Product: Glyceryl trinitrate",[21,28],{"type":22,"name":23,"description":9,"armGroupLabels":24,"otherNames":25},"COMBINATION_PRODUCT","Nicardipine",[9],[26,27],"Labetalol","Methyldopa",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Glyceryl trinitrate","Glyceryltrinitrate based acute blood pressure lowering treatment",[15],[26,33],"Nimotop",null,[36,41],{"name":37,"role":38,"phone":39,"phoneExt":34,"email":40},"Rolf Blauenfeldt, MD, PhD","CONTACT","+4520774053","rolfblau@rm.dk",{"name":42,"role":38,"phone":34,"phoneExt":34,"email":43},"Claus Z Simonsen, MD, PhD","clausimo@rm.dk",[45],{"facility":5,"status":46,"city":47,"state":34,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Aarhus","8200","Denmark","DK",{"type":52,"coordinates":53},"Point",[54,55],10.21076,56.15674,{"lat":55,"lon":54},[58],{"name":59,"role":38,"phone":60,"phoneExt":34,"email":40},"Rolf Blauenfeldt","+4529318244",{"type":62,"investigatorFullName":59,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"PRINCIPAL_INVESTIGATOR","MD, PhD, Associate Professor","100596344","phase-4-nicardipine-for-fast-achievement-of-systolic-bp-targets-in-ich-100596344",false,"NCT07044232","NICardipine for Fast Achievement of Systolic BP Targets in ICH","NICardipine for Fast Achievement of Systolic BP Targets in ICH - a Quasi-randomized, Implementation Trial With Stepwise Rollout of Nicardipin Based Treatment of Hypertension.","NICFAST","Inclusion Criteria:\n\n* Age ≥18 years\n* Acute spontaneous Intracerberal Hemorrhage confirmed by imaging\n* Symptom onset to stroke center admission \\\u003C6 hours\n* Elevated systolic blood pressure (\\>140 mmHg) at admission\n\nExclusion Criteria:\n\n* Secondary causes of ICH (e.g., trauma, vascular malformation)\n* Presumed fatal bleeding at admission\n* Short remaining life expectancy (\\\u003C12 month)","ALL","18 Years",{"count":75,"type":76},88,"ESTIMATED","INTERVENTIONAL",[79],"PHASE4","Quality improvement study with a quasi-randomized design. The study monitors the effect of a gradually implemented treatment algorithm prioritizing intravenous antihypertensives (e.g., nicardipine) over long-acting nitrate patches. It aims to increase the proportion of patients reaching target systolic BP \\\u003C140 mmHg within 1 hour of hospital admission while monitoring safety, clinical outcomes, and healthcare resource utilization.",[82],"Intracerebral Haemorrhage",[82,84,85,86,87],"blood pressure treatment","acute blood pressure treatment","nicardipine","glyceryl trinitrate","2026-06-22",{"date":90,"type":91},"2026-06-24","ACTUAL",{"date":93,"type":91},"2025-10-01",{"date":95,"type":76},"2027-09-30",{"name":5,"class":6},1]