[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100370378":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":12,"centralContacts":31,"locations":37,"responsibleParty":83,"collaborators":86,"id":89,"slug":90,"hasResults":91,"nctId":92,"briefTitle":93,"officialTitle":93,"acronym":12,"eligibilityCriteria":94,"healthyVolunteers":95,"sex":96,"minAge":97,"maxAge":12,"enrollmentInfo":98,"targetDuration":12,"studyType":101,"phases":102,"briefSummary":104,"conditions":105,"keywords":109,"overallStatus":40,"whyStopped":12,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"Benaroya Research Institute","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard of care arm","NO_INTERVENTION","The standard of care group will group will receive the following regimen while inpatient:\n\n* 2% topical lidocaine gel applied to catheter tip as needed for pain, maximum dose of 600mg in 12 hours\n* Acetaminophen 1000mg every 8 hours standing\n* Oxycodone 5mg PO every 4 hours as needed pain\n* Phenazopyridine 100mg TID as needed for urinary burning\n* Senna 1 tab every 12 hours\n* Miralax 17g powder once daily as needed for constipation\n\nThe standard of care group will get the following prescriptions on discharge:\n\n* Oxycodone 5mg every 4 hours as needed pain - 15 tabs\n* Acetaminophen 1000mg every 8 hours standing for two days then as needed\n* Phenazopyridine 100mg TID as needed for urinary burning - 9 tabs\n* Senna 1 tab every 12 hours - 10 tabs",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Multi-modal group","EXPERIMENTAL","The multi-modal group will receive the following regimen while inpatient:\n\n* 2% topical lidocaine gel applied to catheter tip as needed for pain, maximum dose of 600mg in 12 hours\n* Acetaminophen 1000mg every 8 hours standing\n* Ibuprofen 600mg every 6 hours standing\n* Oxycodone 5mg PO every 4 hours as needed pain\n* Phenazopyridine 100mg TID as needed for urinary burning\n* Senna 1 tab every 12 hours\n* Miralax 17g powder once daily as needed for constipation\n* Patient Education (Figures 2 \\& 3)\n\nThe multi-modal group will receive the following prescriptions on discharge:\n\n* Acetaminophen 1000mg every 8 hours standing for two days then as needed - 30 tabs\n* Ibuprofen 600mg every 8 hours standing for two days then as needed - 30 tabs\n* Phenazopyridine 100mg TID as needed for urinary burning - 9 tabs\n* Senna 1 tab every 12 hours - 10 tabs",[18,19],"Drug: Ibuprofen 600 mg","Behavioral: Education",[21,26],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":12},"DRUG","Ibuprofen 600 mg","We'll be adding ibuprofen while trying to limit oxycodone use while hospitalized. Patients will not be discharged with a narcotic.",[14],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":12},"BEHAVIORAL","Education","We'll be adding education to patient's post-operative instructions to aid in their pain control management.",[14],[32],{"name":33,"role":34,"phone":35,"phoneExt":12,"email":36},"Ryan Donahue, MD","CONTACT","2062236600","ryan.donahue@vmmc.org",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Virginia Mason Medical Center","RECRUITING","Seattle","Washington","98101","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-122.33207,47.60621,{"lat":50,"lon":49},[53,55,59,62,64,66,68,70,72,74,76,78,80,81],{"name":33,"role":34,"phone":54,"phoneExt":12,"email":36},"512-484-3214",{"name":56,"role":34,"phone":57,"phoneExt":12,"email":58},"Una Lee, MD","2062236749","una.lee@vmmc.org",{"name":60,"role":61,"phone":12,"phoneExt":12,"email":12},"Kathleen Kobashi, MD","SUB_INVESTIGATOR",{"name":63,"role":61,"phone":12,"phoneExt":12,"email":12},"Alvaro Lucioni, MD",{"name":65,"role":61,"phone":12,"phoneExt":12,"email":12},"Fred Govier, MD",{"name":67,"role":61,"phone":12,"phoneExt":12,"email":12},"Christopher Porter, MD",{"name":69,"role":61,"phone":12,"phoneExt":12,"email":12},"John Corman, MD",{"name":71,"role":61,"phone":12,"phoneExt":12,"email":12},"Thomas Pritchett, MD",{"name":73,"role":61,"phone":12,"phoneExt":12,"email":12},"Christopher Kuhr, MD",{"name":75,"role":61,"phone":12,"phoneExt":12,"email":12},"Dena Moskowitz, MD",{"name":77,"role":61,"phone":12,"phoneExt":12,"email":12},"Neil Hanson, MD",{"name":79,"role":61,"phone":12,"phoneExt":12,"email":12},"Andrew Stamm, MD",{"name":33,"role":61,"phone":12,"phoneExt":12,"email":12},{"name":56,"role":82,"phone":12,"phoneExt":12,"email":12},"PRINCIPAL_INVESTIGATOR",{"type":82,"investigatorFullName":84,"investigatorTitle":85,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Una Lee","Principal Investigator and Attending urologist",[87],{"name":88,"class":6},"Virginia Mason Hospital\u002FMedical Center","100370378","phase-4-optimizing-pain-control-in-transurethral-resection-of-the-prostate-100370378",false,"NCT04102566","Optimizing Pain Control in Transurethral Resection of the Prostate","Inclusion Criteria:\n\n* Are identified as candidates for TURP\n* Are 18 years of age or greater\n* Are proficient in English\n\nExclusion Criteria:\n\n* Have filled an opioid prescription in the last 2 months\n* Have an allergy to a medication included in the protocol\n* Have a history of pelvic radiation\n* Have renal failure (Serum Cr \\> 2.0 mg\u002Fdl), peptic ulcer disease, history of gastric bypass, cirrhosis, or other contraindication precluding use of NSAID's\n* Have liver failure, hepatitis, or alcohol abuse which precludes use of acetaminophen",true,"MALE","18 Years",{"count":99,"type":100},50,"ESTIMATED","INTERVENTIONAL",[103],"PHASE4","The purpose of this study is to develop a multi-modal protocol for pain management after TURP that minimizes opioid use. The investigators hypothesize this approach will provide non-inferior pain control to the current standard of care which includes opioids as the primary agent. The investigators believe this is an important step in reducing the opioid epidemic in surgical patients.",[106,107,108],"Pain","BPH With Urinary Obstruction","BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms",[110,111,112],"postoperative pain","Transurethral resection of the prostate","Multimodal pain control","2019-09-25",{"date":115,"type":116},"2019-09-27","ACTUAL",{"date":118,"type":116},"2017-12-08",{"date":120,"type":100},"2019-12-01",{"name":5,"class":6},1]