[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100406843":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":47,"responsibleParty":70,"collaborators":40,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":40,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":40,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":40,"overallStatus":50,"whyStopped":40,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"The Hospital for Sick Children","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PECS block","EXPERIMENTAL","A PECS block of 0.25 % bupivacaine with epinephrine 1:200000 (below the toxic dose limit of 3 mg\u002Fkg) in divided doses to cover the fascial planes identified in PECS I and PECS II. At the completion of surgery, the wound will be infiltrated with up to 0.2 ml\u002Fkg of 0.25 % bupivacaine into the wound.",[13],"Drug: Bupivacaine 0.25% with epinephrine 1:200000 by PECS block and wound infiltration",{"label":15,"type":16,"description":17,"interventionNames":18},"Infiltration","ACTIVE_COMPARATOR","At the completion of surgery, the EP cardiologist will infiltrate the wound with up to 0.8 ml\u002Fkg of 0.25 % bupivacaine with epinephrine 1:200000.",[19],"Drug: Bupivacaine 0.25% with epinephrine 1:200000 by wound infiltration only",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Bupivacaine 0.25% with epinephrine 1:200000 by PECS block and wound infiltration","The anesthesiologist will administer bupivacaine 0.25% with epinephrine 1:200000 by PECS block after induction of anesthesia before surgical incision. The EP cardiologist will also administer bupivacaine 0.25% with epinephrine 1:200000 by infiltrating the wound after surgery is complete.",[9],[9],{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Bupivacaine 0.25% with epinephrine 1:200000 by wound infiltration only","The EP cardiologist will administer Bupivacaine 0.25% with epinephrine 1:200000 by infiltrating the wound after surgery is complete.",[15],[15],[33],{"name":34,"affiliation":5,"role":35},"Katherine Taylor","PRINCIPAL_INVESTIGATOR",[37,42],{"name":34,"role":38,"phone":39,"phoneExt":40,"email":41},"CONTACT","416-813-7445",null,"katherine.taylor@sickkids.ca",{"name":43,"role":38,"phone":44,"phoneExt":45,"email":46},"Carolyne Pehora","416-813-7654","202406","carolyne.pehora@sickkids.ca",[48],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Hospital for Sick Children","RECRUITING","Toronto","Ontario","M5G 1X8","Canada","CA",{"type":57,"coordinates":58},"Point",[59,60],-79.39864,43.70643,{"lat":60,"lon":59},[63,64,65,68],{"name":34,"role":38,"phone":39,"phoneExt":40,"email":41},{"name":43,"role":38,"phone":44,"phoneExt":45,"email":46},{"name":66,"role":67,"phone":40,"phoneExt":40,"email":40},"Anica Bulic","SUB_INVESTIGATOR",{"name":69,"role":67,"phone":40,"phoneExt":40,"email":40},"Farrukh Munshey",{"type":35,"investigatorFullName":34,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":40,"oldOrganization":40},"Associate Professor","100406843","phase-4-pecs-study-for-cied-implantation-surgery-100406843",false,"NCT04577690","PECS Study for CIED Implantation Surgery","Pectoral Nerve (PECS) Block for Cardiac Implantable Electronic Devices (CIED) Implantation Surgery","Inclusion Criteria:\n\n• All patients 3-18 years undergoing CIED surgery in the chest\n\nExclusion Criteria:\n\n* Children \\\u003C 3 years of age at time of procedure as bupivacaine is not licensed for this age group.\n* No parental or patient consent\n* Allergy to bupivacaine\n* Pregnancy or lactation\n* Any condition or diagnosis, that could in the opinion of the Principal Investigator or delegate interfere with the participant's ability to comply with study instructions, might confound the interpretation of the study results, or put the participant at risk.","ALL","3 Years","18 Years",{"count":83,"type":84},48,"ESTIMATED","INTERVENTIONAL",[87],"PHASE4","We aim to determine whether pectoral nerve block (PECS) performed after induction of anesthesia but before surgical incision results less opioid use in the post operative period compared with local infiltration alone in children undergoing Cardiac Implantable Electronic Device (CIED) surgery.",[90,91,92],"Pain, Postoperative","Child","Adolescent","2026-04-21",{"date":95,"type":96},"2026-04-23","ACTUAL",{"date":98,"type":96},"2019-12-01",{"date":100,"type":84},"2028-01-01",{"name":5,"class":6},1]