[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606855":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":40,"centralContacts":48,"locations":54,"responsibleParty":69,"collaborators":36,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":36,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":36,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":36,"overallStatus":56,"whyStopped":36,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Poznan University of Medical Sciences","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","PLACEBO_COMPARATOR","All participants will receive standard spinal anesthesia for total hip arthroplasty and multimodal postoperative analgesia according to institutional protocol.",[13],"Drug: Ropivacaine 0.5% Injectable Solution",{"label":15,"type":16,"description":17,"interventionNames":18},"PENG + LFCN","ACTIVE_COMPARATOR","Participants in this group will receive an ultrasound-guided pericapsular nerve group (PENG) block combined with a lateral femoral cutaneous nerve (LFCN) block using local anesthetic. To preserve blinding, sham procedures will be performed at the lumbar and sacral erector spinae plane block sites (needle insertion and injection of 1-2 mL normal saline). Standard spinal anesthesia for total hip arthroplasty and multimodal postoperative analgesia will be administered as per institutional protocol.",[19],"Drug: Ropivacaine 0.2% Injectable Solution",{"label":21,"type":16,"description":22,"interventionNames":23},"L-ESPB + S-ESPB","Participants in this group will receive ultrasound-guided lumbar erector spinae plane block (L-ESPB) combined with sacral erector spinae plane block (S-ESPB) using local anesthetic. To preserve blinding, sham procedures will be performed at the pericapsular and lateral femoral cutaneous nerve block sites (needle insertion and injection of 1-2 mL normal saline). Standard spinal anesthesia for total hip arthroplasty and multimodal postoperative analgesia will be provided according to institutional protocol.",[19],[25,32,37],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DRUG","Ropivacaine 0.5% Injectable Solution","All patients will receive standard spinal anesthesia with 0.5% ropivacaine, 10-15 mg intrathecally for total hip arthroplasty.",[9],[31],"Spinal Anesthesia",{"type":26,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"Ropivacaine 0.2% Injectable Solution","Ultrasound-guided pericapsular nerve group (PENG) block and lateral femoral cutaneous nerve (LFCN) block, with sham lumbar and sacral ESPBs.\n\nPENG block: 20 mL of 0.2% ropivacaine. LFCN block: 5 mL of 0.2% ropivacaine. Sham lumbar ESPB: 1-2 mL preservative-free normal saline at lumbar ESPB site. Sham sacral ESPB: 1-2 mL preservative-free normal saline at sacral ESPB site. All patients will receive standard spinal anesthesia with 0.5% ropivacaine, 10-15 mg intrathecally for total hip arthroplasty.",[15],null,{"type":26,"name":33,"description":38,"armGroupLabels":39,"otherNames":36},"Ultrasound-guided lumbar erector spinae plane block (L-ESPB) and sacral erector spinae plane block (S-ESPB), with sham PENG and LFCN blocks.\n\nLumbar ESPB: 20 mL of 0.2% ropivacaine at L3 transverse process level. Sacral ESPB: 20 mL of 0.2% ropivacaine at sacral intermediate crest. Sham PENG block: 1-2 mL preservative-free normal saline at PENG site. Sham LFCN block: 1-2 mL preservative-free normal saline at LFCN site. All patients will receive standard spinal anesthesia with 0.5% ropivacaine, 10-15 mg intrathecally for total hip arthroplasty.",[21],[41,44],{"name":42,"affiliation":5,"role":43},"Malgorzata Reysner","STUDY_CHAIR",{"name":45,"affiliation":46,"role":47},"Tomasz Reysenr, M.D.","Poznan Univesity of Medical Sciences","PRINCIPAL_INVESTIGATOR",[49],{"name":50,"role":51,"phone":52,"phoneExt":36,"email":53},"Malgorzata Reysner, M.D. Ph.D.","CONTACT","+48 61 873 83 03","mreysner@ump.edu.pl",[55],{"facility":5,"status":56,"city":57,"state":36,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"RECRUITING","Poznan","62-701","Poland","PL",{"type":62,"coordinates":63},"Point",[64,65],16.92993,52.40692,{"lat":65,"lon":64},[68],{"name":50,"role":51,"phone":52,"phoneExt":36,"email":53},{"type":70,"investigatorFullName":36,"investigatorTitle":36,"investigatorAffiliation":36,"oldNameTitle":36,"oldOrganization":36},"SPONSOR","100606855","phase-4-peng-vs-l-espb-with-s-espb-for-analgesia-in-total-hip-arthroplasty-100606855",false,"NCT07180979","PENG vs L-ESPB With S-ESPB for Analgesia in Total Hip Arthroplasty","Comparison of Pericapsular Nerve Group (PENG) Block Versus Lumbar Erector Spinae Plane Block (L-ESPB) Combined With Sacral ESPB (S-ESPB) for Analgesia in Total Hip Arthroplasty (THA): A Randomized Clinical Trial","Inclusion Criteria:\n\n* Age ≥ 65 years\n* ASA physical status I-III\n* Elective unilateral THA via posterior or lateral approach\n* Informed consent provided\n\nExclusion Criteria:\n\n* Allergy to study drugs (ropivacaine, dexamethasone)\n* Chronic opioid use (\\>30 MME\u002Fday)\n* Coagulopathy or infection at the injection site\n* BMI \\> 40 kg\u002Fm²\n* Pre-existing motor weakness or neuropathy in the affected limb\n* Cognitive impairment precluding informed consent","ALL","65 Years","100 Years",{"count":82,"type":83},90,"ESTIMATED","INTERVENTIONAL",[86],"PHASE4","The goal of this clinical trial is to evaluate whether different types of regional anesthesia can improve pain control and functional recovery after total hip arthroplasty in adult patients undergoing elective hip replacement surgery.\n\nThe main questions it aims to answer are:\n\nDoes the PENG block reduce opioid use in the first 48 hours after surgery more effectively than the combined L-ESPB + S-ESPB technique? Which method provides better pain relief, preserves muscle strength, and supports earlier mobilization? Researchers will compare the Pericapsular Nerve Group (PENG) block with the combination of Lumbar and Sacral Erector Spinae Plane Blocks (L-ESPB + S-ESPB) to see which provides better pain control, fewer side effects, and faster recovery.\n\nParticipants will:\n\nBe randomly assigned to receive one of the two types of ultrasound-guided regional anesthesia Undergo standard hip replacement surgery under spinal anesthesia Be monitored for pain scores, opioid use, time to first walking, muscle strength, satisfaction, and side effects over the first 48 hours after surgery.",[89,90,91],"Hip Osteoarthritis","Hip Arthropathy","Hip Pain Chronic","2026-05-06",{"date":94,"type":95},"2026-05-07","ACTUAL",{"date":97,"type":95},"2025-09-15",{"date":99,"type":83},"2026-11-30",{"name":5,"class":6},1]