[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100473080":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":35,"centralContacts":40,"locations":48,"responsibleParty":66,"collaborators":27,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":27,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":27,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":100,"overallStatus":51,"whyStopped":27,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"Regionshospitalet Silkeborg","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Corticosteroid injection","ACTIVE_COMPARATOR","Percutaneous needle fasciotomy with corticosteroid injection",[13,14],"Procedure: Percutaneous needle fasciotomy","Drug: Corticosteroid injection",{"label":16,"type":17,"description":18,"interventionNames":19},"Saline injection","PLACEBO_COMPARATOR","Percutaneous needle fasciotomy with saline injection",[13,20],"Other: Saline injection",[22,28,32],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"PROCEDURE","Percutaneous needle fasciotomy","Percutaneous needle fasciotomy ad modum Lermusiaux and Debeyre",[9,16],null,{"type":29,"name":9,"description":30,"armGroupLabels":31,"otherNames":27},"DRUG","Depo-Medrol",[9],{"type":6,"name":16,"description":33,"armGroupLabels":34,"otherNames":27},"Isotonic saline",[16],[36],{"name":37,"affiliation":38,"role":39},"Jeppe Lange, MD, PhD","Regionshospitalet Horsens","STUDY_DIRECTOR",[41,46],{"name":42,"role":43,"phone":44,"phoneExt":27,"email":45},"Laura H Matthiesen, MS, PhD-student","CONTACT","004561281917","lather@rm.dk",{"name":37,"role":43,"phone":27,"phoneExt":27,"email":47},"jepplang@rm.dk",[49],{"facility":50,"status":51,"city":52,"state":27,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Silkeborg Regional Hospital","RECRUITING","Silkeborg","8600","Denmark","DK",{"type":57,"coordinates":58},"Point",[59,60],9.54508,56.1697,{"lat":60,"lon":59},[63,65],{"name":64,"role":43,"phone":44,"phoneExt":27,"email":45},"Laura H Matthiesen, PhD Student",{"name":37,"role":43,"phone":27,"phoneExt":27,"email":47},{"type":67,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"PRINCIPAL_INVESTIGATOR","Laura Houstrup Matthiesen","Medical Student, PhD Student","100473080","phase-4-percutaneous-needle-fasciotomy---corticosteroid-injection-for-dupuytrens-contracture-100473080",false,"NCT05440240","Percutaneous Needle Fasciotomy +\u002F- Corticosteroid Injection for Dupuytren's Contracture","Percutaneous Needle Fasciotomy (PNF) +\u002F- Corticosteroid Injection for Dupuytren's Contracture (DC) Affecting Metacarpophalangeal Joints (MCP) . A Randomized Controlled Trial","Sufficient correction of metacarpophalangeal (MCP) joint during the PNF treatment, defined as \\\u003C20° passive extension deficit (PED), is a prerequisite for inclusion.\n\nInclusion Criteria:\n\n* Dupuytren contracture (DC) of ≥ 20° PED in MCP joint measured with a goniometer\n* DC of either II-V finger\n* Well-defined\u002Fpalpable cord\n\nExclusion Criteria:\n\n* Legally incapacitated\n* Previous study inclusion with another finger ray\n* Isolated proximal interphalangeal (PIP) or distal interphalangeal (DIP) joint contracture, defined as MCP joint contracture \\\u003C 20° PED regardless of the deficit in the PIP or DIP joint\n* Previous hand surgery of the affected finger for any reason\n* Known allergy to the study medication\n* Anticoagulant therapy (Acetylsalicylic acid is NOT an exclusion criterion)\n* Pregnant or lactation\n* Insulin dependent diabetes mellitus\n* Ongoing systemic infection or local infection at the site of the procedure\n* Rheumatoid arthritis\n* Amyloidosis or mucopolysaccharidosis\n* Unable to communicate, cooperate or participate in follow-up","ALL","45 Years","99 Years",{"count":81,"type":82},400,"ESTIMATED","INTERVENTIONAL",[85],"PHASE4","Comparing percutaneous needle fasciotomy +\u002F- corticosteroid injection for Dupuytren's contracture affecting metacarpophalangeal joints. A clinician-initiated, multicenter, randomized controlled trial.",[88,89,90,91,92,93,94,95,96,97,98,99],"Dupuytren Contracture","Dupuytren's Disease","Contracture","Joint Diseases","Musculoskeletal Diseases","Fibroma","Neoplasm, Fibrous Tissue","Neoplasms, Connective Tissue","Neoplasms, Connective and Soft Tissue","Neoplasms by Histologic Type","Neoplasms","Connective Tissue Diseases",[24,101,102],"Corticosteroid","Randomized controlled trial","2023-05-15",{"date":105,"type":106},"2023-05-17","ACTUAL",{"date":108,"type":106},"2023-01-10",{"date":110,"type":82},"2030-03",{"name":5,"class":6},1]