[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640061":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":38,"responsibleParty":59,"collaborators":12,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":12,"eligibilityCriteria":68,"healthyVolunteers":65,"sex":69,"minAge":70,"maxAge":12,"enrollmentInfo":71,"targetDuration":12,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":85,"overallStatus":41,"whyStopped":12,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Wroclaw Medical University","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard of care","NO_INTERVENTION","standard of care (SOC), including recommendation for influenza vaccination in primary care",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Influenza vaccination pre-discharge in patients hospitalized for acute cardiac conditions","EXPERIMENTAL","pre-discharge influenza vaccine administration",[18],"Biological: Influenza vaccination",[20],{"type":21,"name":22,"description":14,"armGroupLabels":23,"otherNames":12},"BIOLOGICAL","Influenza vaccination",[14],[25],{"name":26,"affiliation":5,"role":27},"Jan Biegus, Professor","STUDY_CHAIR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":12,"email":33},"Piotr Kübler Kübler, Professor","CONTACT","48717364240","piotr.kubler@umw.edu.pl",{"name":35,"role":31,"phone":36,"phoneExt":12,"email":37},"Michal Tkaczyszyn, M.D., PhD","48 71 733 11 12","michal.tkaczyszyn@umw.edu.pl",[39],{"facility":40,"status":41,"city":42,"state":12,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Jan Mikulicz Radecki University Hospital in Wroclaw","RECRUITING","Wroclaw","50-556","Poland","PL",{"type":47,"coordinates":48},"Point",[49,50],17.03006,51.10286,{"lat":50,"lon":49},[53,55],{"name":54,"role":31,"phone":36,"phoneExt":12,"email":37},"Michal Tkaczyszyn, M.D, PhD",{"name":56,"role":31,"phone":57,"phoneExt":12,"email":58},"Kamila Florek, M.D.","71 733 11 12","kamila.florek@student.umw.edu.pl",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Michał Tkaczyszyn, MD","Dr","100640061","phase-4-pre-discharge-influenza-vaccination-in-patients-hospitalized-for-acute-cardiac-conditions-100640061",false,"NCT07617376","Pre-discharge Influenza Vaccination in Patients Hospitalized for Acute Cardiac Conditions","Inclusion Criteria:\n\n* Acute cardiac hospitalization,\n* Planned discharge home within the next 48 hours following completion of in-hospital treatment,\n* No prior influenza vaccination for the current influenza season.\n\nExclusion Criteria:\n\n* History of a severe adverse reaction to influenza vaccination,\n* Allergy to any component of the vaccine to be administered,\n* Discharge to another hospital for continuation of treatment or discharge to a long-term care facility,\n* Antibiotic therapy to be continued after discharge.","ALL","18 Years",{"count":72,"type":73},400,"ESTIMATED","INTERVENTIONAL",[76],"PHASE4","Patients hospitalized for acute cardiac conditions-including acute myocardial infarction, acute heart failure, pulmonary embolism, arrhythmias, and hypertensive emergencies-represent a heterogeneous population at very high risk of recurrent cardiovascular events. Influenza infection may act as a trigger for adverse cardiovascular events. Given the persistently low influenza vaccination uptake despite evidence-based benefits observed in vulnerable populations, including patients with cardiac conditions, new strategies to improve vaccination coverage are being explored. Recently, increasing attention has been directed toward an approach already used in fields such as neonatology, where vaccinations are administered prior to hospital discharge.\n\nIn this investigator-initiated, single-center, randomized, open-label interventional study, we will evaluate whether influenza vaccination administered within 24 hours before hospital discharge in patients hospitalized for acute cardiac conditions is safe and effective in reducing subsequent infections, cardiovascular events, and mortality during the 6 months following hospitalization.",[79,80,81,82,83,84],"Myocardial Infarction","Decompensated Chronic Heart Failure","Acute Heart Failure (AHF)","Pulmonary Embolism Acute","Hypertension Emergency","Arrhythmias",[86,87,88],"influenza vaccination","acute cardiac emergencies","pre-discharg vaccination","2026-05-20",{"date":91,"type":92},"2026-06-01","ACTUAL",{"date":94,"type":92},"2025-11-12",{"date":96,"type":73},"2027-07-01",{"name":5,"class":6},1]