[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634187":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":23,"centralContacts":34,"locations":44,"responsibleParty":56,"collaborators":23,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":23,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":23,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":88,"whyStopped":23,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Western Galilee Hospital-Nahariya","OTHER_GOV",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Indomethacin Group","EXPERIMENTAL","Participants receive Indomethacin 100 mg per rectum, administered after induction of anesthesia prior to oocyte retrieval.",[13],"Drug: Indomethacin 100Mg Suppository",{"label":15,"type":10,"description":16,"interventionNames":17},"Paracetamol Group","Participants receive Paracetamol (Acamol) 1,000 mg intravenously, administered after induction of anesthesia prior to oocyte retrieval. Paracetamol Group",[18],"Drug: Paracetamol \u002F Acetaminophen",{"label":20,"type":21,"description":22,"interventionNames":23},"Control Group","NO_INTERVENTION","Participants receive no active preoperative analgesic medication. Oocyte retrieval is performed under standard anesthesia protocols only.",null,[25,30],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":23},"DRUG","Indomethacin 100Mg Suppository","Indomethacin 100 mg administered per rectum after induction of anesthesia, prior to oocyte retrieval. Indomethacin Group",[9],{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":23},"Paracetamol \u002F Acetaminophen","Paracetamol (Acamol) 1,000 mg administered intravenously after induction of anesthesia, prior to oocyte retrieval.",[15],[35,40],{"name":36,"role":37,"phone":38,"phoneExt":23,"email":39},"Raneen Sawaid Kaiyal, Medical Doctor","CONTACT","+972502044422","raneen.sawaid@gmail.com",{"name":41,"role":37,"phone":42,"phoneExt":23,"email":43},"Inbal Paskovetich","9724 9107267","inbalp@gmc.gov.il",[45],{"facility":46,"status":23,"city":47,"state":23,"zip":23,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":23},"Western Galilee Hospital, IVF unit","Nahariya","Israel","IL",{"type":51,"coordinates":52},"Point",[53,54],35.09814,33.00892,{"lat":54,"lon":53},{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","raneen sawaid","Medical Doctor, Fertility Specialist and head of fertility preservation unit","100634187","phase-4-preoperative-indomethacin-and-paracetamol-for-pain-management-during-oocyte-retrieval-in-ivf-patients-100634187",false,"NCT07536425","Preoperative Indomethacin and Paracetamol for Pain Management During Oocyte Retrieval in IVF Patients","Evaluating the Efficacy of Preoperative Indomethacin and Paracetamol for Pain Management During Oocyte Retrieval in IVF Patients A Randomized Controlled Study","Inclusion Criteria:\n\n* Women undergoing oocyte retrieval for IVF or ICSI\n* Age 18-45 years\n* ASA physical status classification I or II\n* Willing and able to provide written informed consent\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to Indomethacin, any NSAID, or Paracetamol\n* History of gastrointestinal bleeding or peptic ulceration\n* Renal impairment (GFR \\\u003C 30 ml\u002Fmin\u002F1.73m² or Creatinine \\> 1.04 mg\u002FdL)\n* Hepatic impairment (ALT \\> 55 U\u002FL, AST \\> upper limit of normal, ALP \\> upper limit of normal, Total Bilirubin \\> 1.2 mg\u002FdL, or Albumin \\\u003C 3.5 g\u002FdL)\n* Participation in another clinical trial that may interfere with the outcomes of this study",true,"FEMALE","18 Years","45 Years",{"count":72,"type":73},177,"ESTIMATED","INTERVENTIONAL",[76],"PHASE4","This is a randomized controlled trial evaluating the efficacy of preoperative analgesic medications - Indomethacin (100 mg per rectum) and Paracetamol\u002FAcamol (1,000 mg intravenously) - for pain management during oocyte retrieval in women undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).",[79,80],"Pain","Oocyte Retrieval",[82,83,84,85,86,87],"Oocyte retrieval","IVF","ICSI","Pain management","Assisted reproductive technology","Numerical Rating Scale","NOT_YET_RECRUITING","2026-04-27",{"date":91,"type":92},"2026-05-04","ACTUAL",{"date":94,"type":73},"2026-04-13",{"date":96,"type":73},"2027-12-31",{"name":5,"class":6},1]