[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599011":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":62,"collaborators":26,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":26,"eligibilityCriteria":71,"healthyVolunteers":72,"sex":73,"minAge":74,"maxAge":26,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":89,"whyStopped":26,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Chulalongkorn University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Tranexamic acid","ACTIVE_COMPARATOR","Tranexamic acid (1 g) 20 ml intravenous preoperation",[13],"Drug: Tranexamic Acid",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Normal saline 20 ml intravenous preoperation",[19],"Other: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Tranexamic Acid","Tranexamic Acid 1 g intravenous preoperation",[9],null,{"type":6,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"normal saline 20 ml intravenous preoperation",[15],[31],{"name":32,"affiliation":5,"role":33},"Vorapong Phupong, M.D.","STUDY_DIRECTOR",[35,39],{"name":32,"role":36,"phone":37,"phoneExt":26,"email":38},"CONTACT","+6626492115","vorapong.p@chula.ac.th",{"name":40,"role":36,"phone":41,"phoneExt":26,"email":42},"Thawit Suesakulpaisal, M.D.","026492115","tsm.2539@gmail.com",[44],{"facility":45,"status":26,"city":46,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University","Bangkok","10330","Thailand","TH",{"type":51,"coordinates":52},"Point",[53,54],100.50144,13.75398,{"lat":54,"lon":53},[57,58,60],{"name":32,"role":36,"phone":41,"phoneExt":26,"email":38},{"name":40,"role":59,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"name":32,"role":61,"phone":26,"phoneExt":26,"email":26},"SUB_INVESTIGATOR",{"type":59,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Vorapong Phupong","Professor","100599011","phase-4-prophylactic-intravenous-tranexamic-acid-on-perioperative-blood-loss-in-pregnant-women-undergoing-cesarean-section-100599011",false,"NCT07078942","Prophylactic Intravenous Tranexamic Acid on Perioperative Blood Loss in Pregnant Women Undergoing Cesarean Section","Effect of Preoperative Prophylactic Intravenous Tranexamic Acid on Perioperative Blood Loss in Pregnant Women Undergoing Cesarean Section : A Randomized Controlled Trial","Inclusion Criteria:\n\n* pregnant women with gestational age 37-42 weeks\n* undergoing cesarean delivery with indication as follows: placenta previa, severe preeclampsia, myoma uteri, fetal macrosomia, polyhydramnios, grand multiparity ≥ 5 deliveries, prolonged labor, etc.\n\nExclusion Criteria:\n\n* history of allergy to tranexamic acid\n* history of venous thromboembolism (Deep vein thrombosis, Pulmonary embolism)\n* history of arterial thrombosis (Myocardial infarction, Stroke)\n* history of seizure, convulsion\n* have underlying of cardiovascular, renal or liver disease\n* using of antiplatelet or anticoagulant within 1 week before operation\n* placenta accreta spectrum\n* abruptio placenta\n* Eclampsia or HELLP (Hemolysis Elevated Liver Low Platelet) syndrome\n* Failed operative vaginal delivery\n* Multifetal gestation",true,"FEMALE","18 Years",{"count":76,"type":77},98,"ESTIMATED","INTERVENTIONAL",[80],"PHASE4","The purpose of this study is to asses the effect of preoperative prophylactic intravenous tranexamic acid on perioperative blood loss in pregnant women undergoing cesarean section",[83],"Pregnant Women Undergoing Cesarean Delivery",[85,86,87,88],"tranexamic acid","blood loss","pregnant women","cesarean delivery","NOT_YET_RECRUITING","2025-07-23",{"date":92,"type":93},"2025-07-28","ACTUAL",{"date":95,"type":77},"2025-07-20",{"date":97,"type":77},"2026-12-31",{"name":5,"class":6},1]