[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628241":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":23,"locations":29,"responsibleParty":42,"collaborators":11,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":11,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":11,"enrollmentInfo":55,"targetDuration":11,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":32,"whyStopped":11,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"University of Baghdad","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"group I maxillary sinus augmenation with xenograft and PTH","EXPERIMENTAL",null,[13],"Procedure: Maxillary sinus augmentation",{"label":15,"type":10,"description":11,"interventionNames":16},"group II maxillary sinus augmenation with xenograft alone",[13],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"PROCEDURE","Maxillary sinus augmentation","Intervention 1 - Control Group\n\nName of Intervention: Bone graft only\n\nType: Procedure \u002F Biological\n\nDescription: Maxillary sinus augmentation using bone graft alone\n\nIntervention 2 - Experimental Group\n\nName of Intervention: Bone graft + PTH\n\nType: Procedure \u002F Drug (PTH)\n\nDescription: Maxillary sinus augmentation using bone graft combined with parathyroid hormone (PTH",[9,15],[24],{"name":25,"role":26,"phone":27,"phoneExt":11,"email":28},"Mohanad Ali Ali Shabat, Msc,PhD student in Oral surgey","CONTACT","009647804305996","mohanadshabat@gmail.com",[30],{"facility":31,"status":32,"city":33,"state":11,"zip":11,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":11},"Baghdad University","RECRUITING","Baghdad","Iraq","IQ",{"type":37,"coordinates":38},"Point",[39,40],44.40088,33.34058,{"lat":40,"lon":39},{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","NIBRAS HAMDAN CHASIB BAIDHANI","Prof. Dr in Oral and Maxillofacial Surgery","100628241","phase-4-radiographical-histomorphometrical-and-biomarker-analysis-after-maxillary-sinus-augmentation-utilizing-xenograft-particulate-bone-graft-mixed-with-parathyroid-hormone-100628241",false,"NCT07459075","Radiographical, Histomorphometrical and Biomarker Analysis After Maxillary Sinus Augmentation Utilizing Xenograft Particulate Bone Graft Mixed With Parathyroid Hormone","Radiographical, Histomorphometrical and Biomarker Analysis After Maxillary Sinus Augmentation Utilizing Xenograft Particulate Bone Graft Mixed With Parathyroid Hormone: A Randomized Controlled Study","Inclusion criteria\n\n* Healthy individuals without any systemic disease\u002Flocal pathological lesion at the sinus zone that compromise the bone healing potential.\n* Fair to good oral hygiene.\n* Patient's age ≥ 18 years.\n* The RBH was 3 mm or less. Atrophic edentulous posterior maxillary ridge (missing tooth or teeth in the sinus zone), with adequate ridge width (≥ 5 mm) to accommodate an average DI diameter and to gain primary implant stability.\n* Healed planned implant insertion site.\n\nExclusion criteria\n\n* Medically compromised patients with any of the following conditions that could interfere with normal healing potential or osseointegration such as uncontrolled diabetes mellitus, currently on chemotherapy, corticosteroid or bisphosphonate, radiotherapy of the head and neck in the past 2 years, bleeding disorders, ongoing pregnancy, thyroid hormones problems and psychiatric disorders.\n* The RBH ˃ 3 mm.\n* Thickness of the SM ˃ 5 mm.\n* Maxillary sinusitis (acute and chronic) or any other pathologies in the MS.\n* Previous MS surgery.\n* Heavy smoking ˃ 20 cigarettes daily and\u002For alcohol abuse.\n* Parafunctional habits such as severe bruxism and clenching.","ALL","18 Years",{"count":56,"type":57},30,"ESTIMATED","INTERVENTIONAL",[60],"PHASE4","This study aimed the to investigate the beneficial effect of combining PTH with bovine-derived bone graft bone in maxillary sinus augmentation.\n\nThere is limited information available about the effect of PTH on maxillary sinus augmentation to achieve a clear understanding of PTH's efficacy in bone regeneration and bone remodelling through radiological, clinical, biomarker, histological and histomorphometric assessment .\n\nObjectives\n\n1. Evaluation of the bone density at the planned implants sites using cone beam computed tomography (CBCT).\n2. Histomorphometry examination of maxillary sinus bone to measure (bone trabeculae, connective tissue, osteoblast, osteocyte) after healing 4 months after augmentation.\n3. Osteopontin as biomarker analysis for bone regeneration and osteoblast activity.\n4. Evaluate the primary stability of implant in upper posterior area filled with PTH (1 34) and bovine-derived bone graft compared to bovine-derived bone graft alone.",[63],"Maxillary Sinus Augmentation",[65],"bone regeneration; bone grafts; orthopaedics; dental implant, PTH.","2026-03-06",{"date":68,"type":69},"2026-03-09","ACTUAL",{"date":71,"type":69},"2025-05-01",{"date":73,"type":57},"2026-11",{"name":5,"class":6},1]