[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621679":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":24,"locations":24,"responsibleParty":25,"collaborators":24,"id":29,"slug":30,"hasResults":31,"nctId":32,"briefTitle":33,"officialTitle":34,"acronym":24,"eligibilityCriteria":35,"healthyVolunteers":36,"sex":37,"minAge":38,"maxAge":24,"enrollmentInfo":39,"targetDuration":24,"studyType":42,"phases":43,"briefSummary":45,"conditions":46,"keywords":48,"overallStatus":50,"whyStopped":24,"lastUpdateSubmitDate":51,"lastUpdatePostDateStruct":52,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":24},{"fullName":5,"class":6},"Tribhuvan University, Nepal","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"75mg Aspirin Arm","EXPERIMENTAL","Interventional",[13],"Drug: Aspirin",{"label":15,"type":16,"description":11,"interventionNames":17},"150mg Aspirin Arm","ACTIVE_COMPARATOR",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","Aspirin","This interventional study is being doe in pregnant women after calculationg their Gestosis score and if Gestosis score of 3 or more, they will be randomised into aspirin 75mg and aspirin 150mg in the ratio 1:1. After their delivery, the result will be recorded as to whether preeclampsia had been prevented.",[15,9],null,{"type":26,"investigatorFullName":27,"investigatorTitle":28,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","Dr. Sunita Pun","Pricipal Investigator","100621679","phase-4-randomized-controlled-study-to-compare-efficacy-of-aspirin-75mg-and-150mg-in-the-prevention-of-preeclampsia-in-high-risk-pregnant-women-100621679",false,"NCT07373756","Randomized Controlled Study to Compare Efficacy of Aspirin 75mg and 150mg In the Prevention of Preeclampsia In High Risk Pregnant Women","Effectiveness Of Aspirin In The Prevention Of Preeclampsia In High Gestosis Scored Women Attending Tertiary Level Hospital In Kathmandu: A Randomized Controlled Trial","Inclusion Criteria:\n\n* • All pregnant women with Gestosis score of 3 or more who consents for the study and aged 18 years and above.\n\nExclusion Criteria:\n\n* • Known hypersensitivity to aspirin, uncontrolled asthma with NSAID sensitivity\n\n  * Bleeding disorders, platelet dysfunction, thrombocytopenia, anticoagulant use, active peptic ulcer, history of GI bleed, severe hepatic\u002F renal disease",true,"FEMALE","18 Years",{"count":40,"type":41},86,"ESTIMATED","INTERVENTIONAL",[44],"PHASE4","Preeclampsia in pregnancy is a dreaded complication which has both fetal and maternal adverse outcomes. Studies and WHO have advocated that this complication can be prevented by Aspirin. However which dose is more effective in preventing preeclampsia, whether 75mg or 150mg, will be known from this study.",[47],"Pregnancy Induced Hypertension (PIH)",[49],"hypertension, preeclampsia, aspirin","NOT_YET_RECRUITING","2026-01-23",{"date":53,"type":54},"2026-01-28","ACTUAL",{"date":56,"type":41},"2026-01-15",{"date":58,"type":41},"2026-12-31",{"name":27,"class":6}]