[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643015":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":41,"locations":46,"responsibleParty":61,"collaborators":64,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":70,"sex":76,"minAge":77,"maxAge":26,"enrollmentInfo":78,"targetDuration":26,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":93,"whyStopped":26,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"National Medical Research Center for Cardiology, Ministry of Health of Russian Federation","OTHER_GOV",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"In-hospital thrombolysis in PCI-center","EXPERIMENTAL","In-hospital thrombolysis with tenecteplase in case of predicted delayed pPCI (\\>60 min after admission in PCI-center). Early tenecteplase, clopidogrel and enoxaparin followed by routine or rescue coronary intervention.",[13,14],"Drug: Single, weight-adjusted i.v. bolus of tenecteplase","Procedure: catheterisation",{"label":16,"type":17,"description":18,"interventionNames":19},"Primary PCI in PCI-center","ACTIVE_COMPARATOR","Standard primary PCI in case of predicted delayed pPCI (\\>60 min after admission in PCI-center).",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Single, weight-adjusted i.v. bolus of tenecteplase","Single, weight-adjusted i.v. bolus of tenecteplase in case of \\>60 min in-hospital delay in PCI center",[9],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"PROCEDURE","catheterisation","Standard primary PCI",[9,16],[33],"Routine or rescue coronary intervention",[35,38],{"name":36,"affiliation":5,"role":37},"Dmitry Pevzner, Doctor of Medical Sciences","STUDY_DIRECTOR",{"name":39,"affiliation":5,"role":40},"Rimma Gulyan","PRINCIPAL_INVESTIGATOR",[42],{"name":39,"role":43,"phone":44,"phoneExt":26,"email":45},"CONTACT","+79152284043","rimmagulyan5@mail.ru",[47],{"facility":5,"status":26,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Moscow","Select A State","121552","Russia","RU",{"type":54,"coordinates":55},"Point",[56,57],37.61781,55.75204,{"lat":57,"lon":56},[60],{"name":39,"role":43,"phone":26,"phoneExt":26,"email":45},{"type":40,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Dmitry Pevzner","Doctor of Medical Sciences, Professor, Head of the Emergency Cardiology Department",[65],{"name":66,"class":67},"AO GENERIUM","INDUSTRY","100643015","phase-4-reperfusion-approach-in-predicted-in-hospital-delay-for-primary-pci-in-stemi-100643015",false,"NCT07641231","Reperfusion Approach in Predicted In-hospital Delay for Primary PCI in STEMI","A Randomized Controlled Study of Reperfusion Strategies in Acute ST-segment Elevation Myocardial Infarction Under Conditions of Anticipated In-hospital Delay in Primary Percutaneous Coronary Intervention Strategy: the Reperfusion Approach in Predicted In-hospital Delay for Primary PCI in STEMI (RAPID-STEMI)","RAPID-STEMI","Inclusion Criteria:\n\n* Age equal or greater than 18 years\n* \"Symptom onset-randomization\" time interval \\\u003C12 hours\n* Predicted \"diagnosis-pPCI\" time interval equal or greater than 120 minutes\n* Predicted \"admission-pPCI\" time interval equal or greater than 60 minutes\n* Informed consent received\n\nExclusion Criteria:\n\n* Medical history, procedures, medication administration or the presence of factors that would in general predispose to bleeding events and\u002For the inability to evaluate the study primary endpoint","ALL","18 Years",{"count":79,"type":80},240,"ESTIMATED","INTERVENTIONAL",[83],"PHASE4","This study aims at evaluating of the effectiveness of in-hospital thrombolysis for ST-segment elevation myocardial infarction in PCI centers under conditions of predicted in-hospital delay (\\>60 min after admission in PCI-center) of PCI. Following randomisation a strategy of early tenecteplase and additional antiplatelet and antithrombin therapy followed by catheterisation within 2-24 hours with timely coronary intervention as appropriate (or by rescue coronary intervention if required) in Group A will be compared to primary PCI performed according to local standards in Group B.",[86],"STEMI - ST Elevation Myocardial Infarction",[88,89,90,91,92],"in-hospital fibrinolysis","STEMI","pharmacoinvasive strategy","myocardial infarction (MI)","thrombolysis","NOT_YET_RECRUITING","2026-06-08",{"date":96,"type":97},"2026-06-11","ACTUAL",{"date":99,"type":80},"2026-05-20",{"date":101,"type":80},"2029-05-20",{"name":5,"class":6},1]