[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569474":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":64,"collaborators":25,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":25,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":25,"enrollmentInfo":76,"targetDuration":25,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":25,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Weill Medical College of Cornell University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"0.5 ml Lidocaine with epinephrine vs. 1.0 ml Lidocaine with epinephrine","EXPERIMENTAL","Each side of the nasal ala will be tested for normal sensation using sterile 30-gauge needles. Other eligibility criteria will be confirmed. Participants in this arm will receive an injection of 0.5ml of Xylocaine + epinephrine 1:100,000 (lidocaine + epinephrine 1:100,000), buffered 1\u002F10 with sodium bicarb into one side of the nose (nasal ala) and 1.0 ml of Xylocaine + epinephrine 1:100,000 (lidocaine + epinephrine 1:100,000), buffered 1\u002F10 with sodium bicarb into the opposite nasal ala. Laterality of each anesthetic volume administration will be randomly assigned for each patient. Subjects will be evaluated for duration of effect of anesthesia every 15 minutes on both sides of the face, until the patient reports return of a sharp sensation upon the pinprick test.",[13,14],"Drug: 0.5 ml lidocaine + epinephrine 1:100,000","Drug: 1.0 ml lidocaine + epinephrine 1:100,000",{"label":16,"type":10,"description":17,"interventionNames":18},"1.0 ml Lidocaine with epinephrine vs 0.5 ml Lidocaine with epinephrine","Each side of the nasal ala will be tested for normal sensation using sterile 30-gauge needles. Other eligibility criteria will be confirmed. Participants in this arm will receive an injection of 1.0ml of Xylocaine + epinephrine 1:100,000 (lidocaine + epinephrine 1:100,000), buffered 1\u002F10 with sodium bicarb into one side of the nose (nasal ala) and 0.5 ml of Xylocaine + epinephrine 1:100,000 (lidocaine + epinephrine 1:100,000), buffered 1\u002F10 with sodium bicarb into the opposite nasal ala. Laterality of each anesthetic volume administration will be randomly assigned for each patient. Subjects will be evaluated for duration of effect of anesthesia every 15 minutes on both sides of the face, until the patient reports return of a sharp sensation upon the pinprick test.",[13,14],[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","0.5 ml lidocaine + epinephrine 1:100,000","0.5 ml lidocaine + epinephrine 1:100,000, buffered 1\u002F10 with sodium bicarb",[9,16],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"1.0 ml lidocaine + epinephrine 1:100,000","1.0 ml lidocaine + epinephrine 1:100,000, buffered 1\u002F10 with sodium bicarb",[9,16],[31],{"name":32,"affiliation":5,"role":33},"Kira Minkis, MD, PhD","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Benedict Ho, BA","CONTACT","646-962-6647","beh2024@med.cornell.edu",{"name":41,"role":37,"phone":38,"phoneExt":25,"email":42},"Kira Minkis, MD PhD","kim9036@med.cornel.edu",[44],{"facility":45,"status":46,"city":47,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Weill Cornell Medicine","RECRUITING","New York","10021","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-74.00597,40.71427,{"lat":55,"lon":54},[58,61,63],{"name":32,"role":37,"phone":59,"phoneExt":25,"email":60},"(646) 962-0033","kim9036@med.cornell.edu",{"name":36,"role":37,"phone":62,"phoneExt":25,"email":39},"9175025230",{"name":32,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":65,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100569474","phase-4-split-face-study-of-the-duration-of-local-anesthetics---fourth-arm-100569474",false,"NCT06694714","Split Face Study of the Duration of Local Anesthetics - Fourth Arm","Characterizing and Comparing the Duration of Local Anesthetic in Dermatologic Surgery - Fourth Arm","Inclusion Criteria:\n\n* Male or female ≥ 18 years of age\n* Normal skin sensation at both nasal ala assessed by pinprick\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Previous adverse reaction to local anesthetic or any components of the local anesthetics being evaluated\n* Pregnant or breastfeeding volunteers (assessed by self-report)\n* Patients taking monoamineoxidase inhibitors (MAOI) or antidepressants of the triptyline or imipramine types",true,"ALL","18 Years",{"count":77,"type":78},35,"ESTIMATED","INTERVENTIONAL",[81],"PHASE4","This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for. The investigators will investigate the role of anesthetic volume on the duration of action at highly vascular sites.",[84],"Anesthesia, Local","2026-01-20",{"date":87,"type":88},"2026-01-22","ACTUAL",{"date":90,"type":88},"2025-01-21",{"date":92,"type":78},"2027-06-01",{"name":5,"class":6},1]