[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617249":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":60,"collaborators":26,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":26,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":26,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":39,"whyStopped":26,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Rhode Island Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Ropivacaine","ACTIVE_COMPARATOR","30 ml of 0.25% ropivacaine; No dexmedetomidine",[13],"Drug: Ropivacaine",{"label":15,"type":16,"description":17,"interventionNames":18},"Ropivacaine plus Dexmedetomidine","EXPERIMENTAL","30 ml of 0.25% ropivacaine; 1 mcg\u002Fkg of dexmedetomidine",[19,13],"Drug: Dexmedetomidine",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Dexmedetomidine","Participants in the experimental arm receive a preoperative suprainguinal fascia iliaca block consisting of 30 mL of 0.25% ropivacaine combined with perineural dexmedetomidine at a dose of 1 mcg\u002Fkg.",[15],null,{"type":22,"name":9,"description":28,"armGroupLabels":29,"otherNames":26},"In the experimental arm, ropivacaine (30 mL of 0.25%) is administered with dexmedetomidine.\n\nIn the active comparator arm, ropivacaine (30 mL of 0.25%) is administered alone without any dexmedetomidine medication.",[9,15],[31],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Vendhan Ramanujam, M.D.","CONTACT","401-444-5172","vramanujam@brownhealth.org",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"The Miriam Hospital","RECRUITING","Providence","Rhode Island","02906","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-71.41283,41.82399,{"lat":49,"lon":48},[52,56],{"name":53,"role":33,"phone":54,"phoneExt":26,"email":55},"Renee Dupre","401-793-4575","rdupre@brownhealth.org",{"name":57,"role":33,"phone":58,"phoneExt":26,"email":59},"Mark Kendall, M.D.","401-444-4722","mark.kendall@brownhealth.org",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Vendhan Ramanujam","Principal Investigator","100617249","phase-4-suprainguinal-fascia-iliaca-block-with-vs-without-dexmedetomidine-100617249",false,"NCT07316166","Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine","Comparison of Suprainguinal Fascia Iliac Block With and Without Dexmedetomidine as an Adjunct to Ropivacaine for Postoperative Analgesia Following Hip Surgery: a Randomized, Double-blinded Study.","Inclusion Criteria:\n\n* Patients undergoing elective total hip arthroplasty\n* 18-80 years old\n* ASA 1-3 classifications\n\nExclusion Criteria:\n\n* ASA classification of 4 or greater\n* Infection at the site of nerve blockade\n* Coagulopathy\n* Known allergy to study medications\n* Chronic opioid consumption (\\>3 months)\n* Currently using lidocaine patches\n* Pre-existing neuropathy\n* A history of CVA\n* High grade atrioventricular block (cardiac conduction system impairment)\n* Organ dysfunction (cardiac failure, respiratory failure, end stage renal disease, hepatic dysfunction, hypoalbuminemia)\n* Morbid obesity (≥40 kg\u002Fm2)\n* Prior surgery in supra and\u002For infrainguinal region\n* Non-English-speaking participants","ALL","18 Years","80 Years",{"count":75,"type":76},120,"ESTIMATED","INTERVENTIONAL",[79],"PHASE4","The investigators are evaluating postoperative outcomes in patients undergoing hip replacement surgery performed with either spinal or general anesthesia, who also receive a suprainguinal fascia iliaca block using either perineural ropivacaine alone or ropivacaine combined with dexmedetomidine.",[82],"Postoperative Pain Management",[84,85],"Hip Surgery","Nerve block","2026-03-24",{"date":88,"type":89},"2026-03-25","ACTUAL",{"date":91,"type":89},"2026-01-20",{"date":93,"type":76},"2027-06",{"name":5,"class":6},1]