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The patient or guardian agrees to the study protocol and the schedule of clinical follow-up, and provides informed, written consent, as approved by the appropriate Institutional Review Board\u002FEthical Committee of the respective clinical site\n\nExclusion Criteria:\n\n1. Angiographic exclusion criteria: any of the followings 1. Bypass graft lesions 2. Lesions in which impaired delivery of imaging catheters is expected:\n\n   * Extreme angulation (≥90°) proximal to or within the target lesion.\n   * Excessive tortuosity (≥ two 45° angles) proximal to or within the target lesion.\n   * Heavy calcification proximal to or within the target lesion.\n2. In-stent restenosis\n3. Hypersensitivity or contraindication to device material and its degradants and cobalt, chromium, nickel, platinum, tungsten, acrylic and fluoro polymers that cannot be adequately pre-medicated.\n4. Persistent thrombocytopenia (platelet count \\\u003C80,000\u002Fl)\n5. 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Cardiogenic shock at the index admission\n14. Patient's pregnant or breast-feeding\n15. Active bleeding or extreme-risk for major bleeding (e.g. active peptic ulcer disease, gastrointestinal pathology with a high risk for bleeding, malignancies with a high risk for bleeding)\n16. Unwillingness or inability to comply with the procedures described in this protocol.","ALL","19 Years",{"count":415,"type":416},3944,"ESTIMATED","INTERVENTIONAL",[419],"PHASE4","Objectives: To assess the safety of tailored antiplatelet therapy (short DAPT followed by P2Y12 inhibitor alone strategy) in patients who received optimized DES implantation guided by intravascular imaging (IVUS or OCT)\n\nHypothesis: Tailored antiplatelet strategy (short DAPT followed by P2Y12 inhibitor alone) is superior to conventional antiplatelet strategy in terms of clinically relevant bleeding and noninferior for ischemic composite adverse events in patients who received intravascular imaging-guided optimized DES implantation. 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