[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589363":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":67,"collaborators":26,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":26,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":26,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"King Abdulaziz University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Dexamethasone Group","EXPERIMENTAL","Patient received 4 milligrams of dexamethasone",[13],"Drug: Dexamethasone Sodium Phosphate Injection",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","PLACEBO_COMPARATOR","Patient received 4 milligrams of normal saline solution",[19],"Other: Normal Saline (Placebo)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Dexamethasone Sodium Phosphate Injection","Patients will receive 4 milligrams of dexamethasone submucosal injection next to the extraction site.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Normal Saline (Placebo)","Patients will receive 4 milligrams of normal saline solution next to the extraction site.",[15],[32,37],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Lojain Bassyoni, BDS, MSc, FRCDC","CONTACT","00966504623553","lbassyoni@kau.edu.sa",{"name":38,"role":34,"phone":39,"phoneExt":26,"email":40},"Razan Baabdullah, BDS, MSc, FRCDC","00966555015167","rmsbaabdullah@kau.edu.sa",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"King Abdulaziz University, Faculty of Dentistry","RECRUITING","Jeddah","Mecca Region","Saudi Arabia","SA",{"type":50,"coordinates":51},"Point",[52,53],39.18624,21.49012,{"lat":53,"lon":52},[56,57,60,62,65],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"name":58,"role":59,"phone":26,"phoneExt":26,"email":26},"Lujain Bassyoni, BDS, MS, FRCDC","PRINCIPAL_INVESTIGATOR",{"name":61,"role":59,"phone":26,"phoneExt":26,"email":26},"Razan Baabdullah, BDS, MS, FRCDC",{"name":63,"role":64,"phone":26,"phoneExt":26,"email":26},"Mohammed Bajunaid, BDS","SUB_INVESTIGATOR",{"name":66,"role":64,"phone":26,"phoneExt":26,"email":26},"Badr Alharthi, BDS",{"type":59,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Lojain Bassyoni","Oral and Maxillofacial Surgery Consultant and Assistant Professor","100589363","phase-4-the-effect-of-dexamethasone-submucosal-injection-after-surgical-extraction-of-lower-impacted-third-molars-on-trismus-and-edema-100589363",false,"NCT06953440","The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema","The Effect of Dexamethasone Submucosal Injection After Third Molar Surgery on Trismus and Edema","Inclusion Criteria:\n\n* Patients with impacted lower third molars requiring surgical extraction.\n* Adults over the age of 18 years old.\n* American Society of Anaesthesiologists (ASA) 1, and ASA 2\n\nExclusion Criteria:\n\n* Patients with preoperative intraoral or extraoral swelling.\n* Patients requiring simple extraction (Class I group A according to Pell and ---Gregory classification).\n* Patients with uncontrolled systemic disease such as uncontrolled diabetic - patients.\n* Patients who are allergic to corticosteroids.\n* Patients who are contraindicated to use corticosteroids such as uncontrolled diabetic patients, and osteoporotic patients.\n* Patients who require extraction of additional teeth at the same visit.","ALL","18 Years","65 Years",{"count":81,"type":82},66,"ESTIMATED","INTERVENTIONAL",[85],"PHASE4","This clinical trial aims to investigate whether dexamethasone decreases edema and trismus in adults undergoing lower third molar surgical extraction.\n\nThe main question it aims to answer is:\n\nDoes dexamethasone submucosal injection have a positive impact on trismus and edema after third molar surgery compared to conventional postoperative prescription?\n\nParticipants will:\n\n* Be administered with dexamethasone submucosal injection or a placebo after the surgery.\n* Visit the clinic three times the week after the extraction for follow-up.",[88,89],"Swelling\u002F Edema","Trismus",[91,92,93,94,95,96],"Extraction","third molar","wisdom teeth","dexamethasone","steroids","submucosal","2025-04-23",{"date":99,"type":100},"2025-05-01","ACTUAL",{"date":102,"type":100},"2024-02-01",{"date":104,"type":82},"2025-06-30",{"name":5,"class":6},1]