[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100377294":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":41,"centralContacts":60,"locations":67,"responsibleParty":91,"collaborators":27,"id":94,"slug":95,"hasResults":96,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":27,"eligibilityCriteria":100,"healthyVolunteers":96,"sex":101,"minAge":102,"maxAge":103,"enrollmentInfo":104,"targetDuration":27,"studyType":107,"phases":108,"briefSummary":110,"conditions":111,"keywords":27,"overallStatus":70,"whyStopped":27,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"Beijing Tsinghua Chang Gung Hospital","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"PAP plus medication","EXPERIMENTAL","patients treated by both PAP and medication",[13,14,15],"Device: non-invasive positive airway pressure","Drug: Methylprednisolone Hemisuccinate","Drug: Ginaton",{"label":17,"type":18,"description":19,"interventionNames":20},"medication","ACTIVE_COMPARATOR","patients treated by medication only",[14,15],[22,28,35],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DEVICE","non-invasive positive airway pressure","non-invasive positive airway pressure is the first-line treatment for obstructive sleep apnea",[9],null,{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"DRUG","Methylprednisolone Hemisuccinate","Methylprednisolone is the first-line treatment of idiopathic sudden sensorineural hearing loss",[9,17],[34],"Methylprednisolone, MP",{"type":29,"name":36,"description":37,"armGroupLabels":38,"otherNames":39},"Ginaton","ginnaton is ginkgo biloba extract",[9,17],[40],"Ginkgo biloba extract,GBE",[42,46,49,52,54,56,58],{"name":43,"affiliation":44,"role":45},"Juanjuan Gao, MD","Beijing Tsinghua Changung Hospital","PRINCIPAL_INVESTIGATOR",{"name":47,"affiliation":44,"role":48},"jingying Ye, MD","STUDY_CHAIR",{"name":50,"affiliation":44,"role":51},"Haijin Yi, MD","STUDY_DIRECTOR",{"name":53,"affiliation":44,"role":45},"Mu He, MD",{"name":55,"affiliation":44,"role":45},"Xin Cao, MA",{"name":57,"affiliation":44,"role":45},"Xingxing Lu, MA",{"name":59,"affiliation":44,"role":45},"Sichao Liang, MA",[61,66],{"name":62,"role":63,"phone":64,"phoneExt":27,"email":65},"Jingying Ye, MD","CONTACT","+86-13701396970","yejingying@163.vip.com",{"name":50,"role":63,"phone":27,"phoneExt":27,"email":27},[68],{"facility":69,"status":70,"city":71,"state":72,"zip":73,"country":74,"countryCode":75,"cosmosGeoPoint":76,"geoPoint":81,"contacts":82},"Beijing Tsinhgua Changgung Hospital","RECRUITING","Beijing","Beijing Municipality","100028","China","CN",{"type":77,"coordinates":78},"Point",[79,80],116.39723,39.9075,{"lat":80,"lon":79},[83,87],{"name":84,"role":63,"phone":85,"phoneExt":27,"email":86},"Xin Cao","86-15810519277","caoxin19860201@163.com",{"name":88,"role":63,"phone":89,"phoneExt":27,"email":90},"Mu He","86-15210588954","muhe2009@qq.com",{"type":45,"investigatorFullName":92,"investigatorTitle":93,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"Ye Jingying","Director of the dept. of Otolaryngology, Head and Neck Surgery, and Director of the Center of Sleep Medicine","100377294","phase-4-the-effect-of-pap-on-isshl-comorbided-with-osa-100377294",false,"NCT04192656","The Effect of PAP on ISSHL Comorbided With OSA","The Effect of Positive Airway Pressure on Idiopathic Sudden Sensorineural Hearing Loss Comorbided With Obstructive Sleep Apnea: A Clinical Randomized Controlled Study","Inclusion Criteria:\n\n1. aged \\>= 18 and \\\u003C= 70,\n2. diagnosed with OSA by full-night in-lab or home-stay PSG according to AASM 2012 criteria, and AHI \\> 15\u002Fh,\n3. diagnosed with ISSHL by AAO-HNS 2019 criteria,\n4. ISSHL onset within 1 week.\n\nExclusion Criteria:\n\n1. sudden hearing loss with certain causes,\n2. with severe comorbid diseases,\n3. pregnant or breast-feeding women,\n4. AHI \\\u003C= 15\u002Fh,\n5. hearing threshold recovered \\> 50% when included,\n6. previously regularly treated with PAP.","ALL","18 Years","70 Years",{"count":105,"type":106},102,"ESTIMATED","INTERVENTIONAL",[109],"PHASE4","This clinical randomized controlled study is to explore the effect of positive airway pressure(PAP) on patients in Beijing Tsinghua Changgung Hospital diagnosed with both idiopathic sudden sensorineural hearing loss comorbided(ISSHL) and obstructive sleep apnea(OSA) between Dec. 2019 to Dec. 2029.",[112,113],"Sudden Hearing Loss","Obstructive Sleep Apnea","2019-12-09",{"date":116,"type":117},"2019-12-10","ACTUAL",{"date":119,"type":117},"2019-11-01",{"date":121,"type":106},"2029-12",{"name":5,"class":6},1]