[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576207":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":31,"centralContacts":32,"locations":42,"responsibleParty":56,"collaborators":31,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":31,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":31,"enrollmentInfo":69,"targetDuration":31,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":82,"overallStatus":44,"whyStopped":31,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Rush University Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Constrained condylar (CCK)","ACTIVE_COMPARATOR","Once patient meets inclusion criteria, they'll be randomized prior to surgery to a specific CCK implant design. All surgeries will be done at the approved hospital or ASC and if the allocated component isn't used, the patient will still be followed post operatively and remain in the study.",[13],"Device: Constrained Condylar bearing",{"label":15,"type":10,"description":16,"interventionNames":17},"Posterior Stabilized (PS) bearing","Once patient meets inclusion criteria, they'll be randomized prior to surgery to a specific PS implant design. All surgeries will be done at the approved hospital or ASC and if the allocated component isn't used, the patient will still be followed post operatively and remain in the study.",[18],"Device: posterior stabilized bearing",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Constrained Condylar bearing","Patients in this intervention will receive a CCK bearing component",[9],[26],"CCK",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"posterior stabilized bearing","Patients in this intervention will receive a PS bearing component",[15],null,[33,38],{"name":34,"role":35,"phone":36,"phoneExt":31,"email":37},"Omary Behery, MD","CONTACT","630-339-2230","omar.behery@rushortho.com",{"name":39,"role":35,"phone":40,"phoneExt":31,"email":41},"Anne DeBenedetti, MSc","312-432-2468","anne.debenedetti@rushortho.com",[43],{"facility":5,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":31},"RECRUITING","Chicago","Illinois","60612","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-87.65005,41.85003,{"lat":54,"lon":53},{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Omar Behery","Principle Investigator","100576207","phase-4-the-use-of-cck-vs-ps-in-revision-tkas-100576207",false,"NCT06782295","The Use of CCK vs PS in Revision TKAs","A Prospective Randomized Controlled Trial Comparing Constrained Condylar vs Posterior Stabilized Articulations in Revision Total Knee Arthroplasty","Inclusion criteria:\n\n* Patients between 18-80 years of age\n* Patients who are undergoing both femoral and tibial component revisions, or isolated femoral component revisions with a retained tibial component that is compatible with PS or CCK bearings\n* Patients who are at least 6-weeks out from primary TKA surgery, with complete pre-operative and post-operative knee radiographs obtained at standard of care perioperative visits (AP\u002Flateral and patellar views)\n* Patients undergoing rTKA for indications including aseptic component loosening, flexion or extension coronal or sagittal instability, component malalignment, arthrofibrosis, patellar maltracking, reimplantation following single or two-stage exchange revision for prosthetic joint infection or bearing surface wear when femoral or tibial component revision is indicated.\n* The use of revision total knee arthroplasty systems which have PS and CCK bearing options including different degree options of coronal and rotational constraint (to be individually randomized per constrained option):\n* Zimmer Biomet Persona, NexGen, or Vanguard\n* Smith and Nephew Legion\n* DJO \u002F Enovis Empowr\n* Stryker Triathlon\n* Link SymphoKnee\n* Depuy Attune sion Criteria:\n\nExclusion Criteria:\n\nPatients undergoing rTKA with a hinged implant, or pre-operatively determined to require CCK bearing rTKA, \\> 80 years of age, or those requiring rTKA less than 6-weeks from the primary TKA,\n\nPatients undergoing rTKA for bearing exchange only rTKA, isolated tibial component rTKA\n\nPatients with pre-operative diagnosis of extensor mechanism disruption or collateral ligament incompetence or with a compromised soft tissue envelope requiring pre-pre-operative plastic surgery evaluation and planned soft tissue coverage.\n\n\\-","ALL","18 Years",{"count":70,"type":71},170,"ESTIMATED","INTERVENTIONAL",[74],"PHASE4","This study aims to compare the clinical impact of Constrained Condylar versus Posterior Stabilized Knee (PS) bearings on patient satisfaction and surgical outcomes including mid-term survivorship among patients undergoing revision total knee arthroplasty.",[77,78,79,80,81],"Aseptic Loosening of Prosthetic Joint","Instability of Prosthetic Joint","Reimplantation for Periprosthetic Joint Infection","Femoral Revision Indicated","Tibial Component Revision",[83,84,85,86,87],"revision total knee replacement","cck","ps","coronal instability","sagittal instability","2025-11-13",{"date":90,"type":91},"2025-11-14","ACTUAL",{"date":93,"type":91},"2025-07-01",{"date":95,"type":71},"2038-07-01",{"name":5,"class":6},1]