[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100549384":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":35,"responsibleParty":52,"collaborators":20,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":20,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":20,"enrollmentInfo":63,"targetDuration":20,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":20,"overallStatus":38,"whyStopped":20,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Weill Medical College of Cornell University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy","EXPERIMENTAL","Participants will receive one bottle of L-Phenylalanine 500 mg Veg Capsule product on Day 0. All subjects will be asked to start taking the supplement on Day 1 continuing until Day 14. They will be asked to take 2x 500 mg capsules in the morning and 1x 500 mg capsule in the evening daily for 14 days.",[13],"Drug: L-Phenylalanine 500 mg Veg Capsule product",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","L-Phenylalanine 500 mg Veg Capsule product","500 mg Veg Capsule product",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Iliyan D Iliev, PhD","PRINCIPAL_INVESTIGATOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":20,"email":30},"Emilia T Vignogna, BS","CONTACT","505-259-4995","etv4001@med.cornell.edu",{"name":32,"role":28,"phone":33,"phoneExt":20,"email":34},"Tsering D Sherpa-Ngima, BSc","929-328-9571","tss4002@med.cornell.edu",[36],{"facility":37,"status":38,"city":39,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Belfer Research Building","RECRUITING","New York","10022","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-74.00597,40.71427,{"lat":47,"lon":46},[50,51],{"name":27,"role":28,"phone":29,"phoneExt":20,"email":30},{"name":23,"role":24,"phone":20,"phoneExt":20,"email":20},{"type":53,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100549384","phase-4-understanding-the-efficacy-of-dietary-supplement-on-fungal-mycobiota-in-healthy-volunteers-a-pilot-study-100549384",false,"NCT06433310","Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study","Inclusion Criteria:\n\n* Male or female adults over the age of 18 years\n\nExclusion Criteria:\n\n* History of a diagnosis of any gastrointestinal condition, such as inflammatory bowel syndrome or disease\n* Antibiotic usage within the past two weeks\n* Antifungal usage within the past month\n* Allergy to L-Phenylalanine or individuals with phenylketonuria (PKU)\n* Adults taking medications known to interact with L-phenylalanine supplements, such as Monoamine Oxidase Inhibitors (MOAI), L-DOPA, and some antipsychotic drugs (complete and extensive drug list will be provided to interested participants during screening)\n* Pregnant or nursing women",true,"ALL","18 Years",{"count":64,"type":65},20,"ESTIMATED","INTERVENTIONAL",[68],"PHASE4","The purpose of this study is to explore how the dietary supplement L-Phenylalanine affects the production of the metabolite phenylpropionic acid (PPA) and changes fungal populations of the gut microbiome.",[71,72,73,74,75],"Gut Microbiome","Gut Health","Dietary Supplement","L-Phenylalanine","Phenylpropionic Acid","2026-06-23",{"date":78,"type":79},"2026-06-26","ACTUAL",{"date":81,"type":79},"2024-10-17",{"date":83,"type":65},"2027-12-31",{"name":5,"class":6},1]