[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100333455":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":45,"centralContacts":49,"locations":59,"responsibleParty":79,"collaborators":53,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":86,"acronym":53,"eligibilityCriteria":87,"healthyVolunteers":84,"sex":88,"minAge":89,"maxAge":53,"enrollmentInfo":90,"targetDuration":53,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":53,"overallStatus":62,"whyStopped":53,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"University of Texas Southwestern Medical Center","OTHER",[8,15,21],{"label":9,"type":10,"description":11,"interventionNames":12},"Low vit-D, Ergocalciferol","EXPERIMENTAL","Low serum vitamin D level, split by use or non-use of systemic corticosteroid. Vitamin D2 (Ergocalciferol) 50,000 units will be given by mouth once a week for 12 weeks, then once a month for 12 weeks.\n\nDaily dietary requirement (calcium citrate with vitamin D2 (200 mg\u002F250 Units tablets, 4 tablets per day) will be given by mouth for 24 weeks).",[13,14],"Drug: Ergocalciferol","Drug: Calcium Citrate with Vitamin D2",{"label":16,"type":17,"description":18,"interventionNames":19},"Low vit-D, Placebo","PLACEBO_COMPARATOR","Low serum vitamin D level, split by use or non-use of systemic corticosteroid. Placebo capsules of identical size and appearance will be given by mouth once a week for 12 weeks, then once a month for 12 weeks.\n\nDaily dietary requirement (calcium citrate with vitamin D2 (200 mg\u002F250 Units tablets, 4 tablets per day) will be given by mouth for 24 weeks).",[20,14],"Drug: Placebo",{"label":22,"type":6,"description":23,"interventionNames":24},"Normal vit-D, control","Normal serum vitamin D level, split by use or non-use of systemic corticosteroid.\n\nDaily dietary requirement (calcium citrate with vitamin D2 (200 mg\u002F250 Units tablets, 4 tablets per day) will be given by mouth for 24 weeks).",[14],[26,33,39],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DRUG","Ergocalciferol","Vitamin D2 50,000 units",[9],[32],"Vitamin D2",{"type":27,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"Placebo","Sugar pill manufactured to mimic ergocalciferol 50,000 units",[16],[38],"Placebo oral tablets",{"type":27,"name":40,"description":41,"armGroupLabels":42,"otherNames":43},"Calcium Citrate with Vitamin D2","To meet the recommended minimum daily dietary requirements",[9,16,22],[44],"Citracal",[46],{"name":47,"affiliation":5,"role":48},"Connie Hsia, MD","PRINCIPAL_INVESTIGATOR",[50,55],{"name":47,"role":51,"phone":52,"phoneExt":53,"email":54},"CONTACT","2146483426",null,"Connie.Hsia@utsouthwestern.edu",{"name":56,"role":51,"phone":57,"phoneExt":53,"email":58},"Khashayar Sakhaee, MD","2146480324","Khashayar.Sakhaee@utsouthwestern.edu",[60],{"facility":61,"status":62,"city":63,"state":64,"zip":65,"country":66,"countryCode":67,"cosmosGeoPoint":68,"geoPoint":73,"contacts":74},"University of Texas Southwestern Medical Center, and Parkland Health and Hospital System","RECRUITING","Dallas","Texas","75390-9034","United States","US",{"type":69,"coordinates":70},"Point",[71,72],-96.80667,32.78306,{"lat":72,"lon":71},[75,76],{"name":47,"role":48,"phone":53,"phoneExt":53,"email":53},{"name":77,"role":78,"phone":53,"phoneExt":53,"email":53},"Khashaya Sakhaee, MD","SUB_INVESTIGATOR",{"type":48,"investigatorFullName":80,"investigatorTitle":81,"investigatorAffiliation":5,"oldNameTitle":53,"oldOrganization":53},"Connie C W Hsia","Professor of Internal Medicine","100333455","phase-4-vitamin-d-homeostasis-in-sarcoidosis-100333455",false,"NCT03621553","Vitamin D Homeostasis in Sarcoidosis","Inclusion Criteria:\n\n* Stable medical condition defined as no hospitalization or emergency room visit in the previous 3 months\n* No evidence of active pulmonary or systemic infection\n* No other active inflammatory disease,\n* No active malignancy.\n* Normal serum ionized calcium level\n\nExclusion Criteria:\n\n* Hospitalization or emergency room visit in the previous 3 months\n* Evidence of active pulmonary or systemic infection\n* Evidence of active other inflammatory disease\n* Evidence of active malignancy\n* Elevated serum ionized calcium level","ALL","21 Years",{"count":91,"type":92},90,"ESTIMATED","INTERVENTIONAL",[95],"PHASE4","This study evaluates the relationship between vitamin-D status and severity of sarcoidosis, and the effects of vitamin-D repletion in vitamin-D insufficient patients with sarcoidosis. Half the patients with sarcoidosis who are vitamin-D insufficient will receive standard vitamin-D supplementation via standard regimen while the other half will receive a placebo. Sarcoidosis patients who are vitamin-D sufficient will also act as controls.",[98,99],"Sarcoidosis","Vitamin D Insufficiency","2025-12-30",{"date":102,"type":103},"2026-01-02","ACTUAL",{"date":105,"type":103},"2010-07-01",{"date":107,"type":92},"2026-12-30",{"name":5,"class":6},1]