[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100424754":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":58,"centralContacts":62,"locations":71,"responsibleParty":88,"collaborators":51,"id":91,"slug":92,"hasResults":93,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":97,"eligibilityCriteria":98,"healthyVolunteers":93,"sex":99,"minAge":100,"maxAge":101,"enrollmentInfo":102,"targetDuration":51,"studyType":105,"phases":106,"briefSummary":108,"conditions":109,"keywords":51,"overallStatus":74,"whyStopped":51,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":124},{"fullName":5,"class":6},"The University of Texas Health Science Center, Houston","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"MOUD induction and behavioral interventions among opioid-dependent youths","EXPERIMENTAL","Induction into medication for opioid use disorder (MOUD) treatment and behavioral interventions",[13,14,15,16,17,18],"Drug: Buprenorphine, Naloxone Drug Combination","Behavioral: Individual Counseling","Behavioral: Peer Recovery Support Services","Behavioral: Support Group","Behavioral: Referral to Medication Management","Behavioral: Assertive Outreach",[20,27,34,41,47,52],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Buprenorphine, Naloxone Drug Combination","8mg of buprenorphine\u002F2mg of naloxone to initiate MOUD treatment and bridge, if necessary, until referral to MOUD clinic can be made for ongoing treatment",[9],[26],"Suboxone",{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"BEHAVIORAL","Individual Counseling","One-on-one counseling with a licensed chemical dependency counselor",[9],[33],"Therapy",{"type":28,"name":35,"description":36,"armGroupLabels":37,"otherNames":38},"Peer Recovery Support Services","24\u002F7 support from our team of certified peer recovery support specialists to assist with emotional support and case management",[9],[39,40],"Peer Coaching","Recovery Coaching",{"type":28,"name":42,"description":43,"armGroupLabels":44,"otherNames":45},"Support Group","Referrals to youth-focused support groups and eventual creation of in-house youth-focused support groups",[9],[46],"Group Therapy",{"type":28,"name":48,"description":49,"armGroupLabels":50,"otherNames":51},"Referral to Medication Management","Study staff will refer patients to long-term MOUD providers in the community",[9],null,{"type":28,"name":53,"description":54,"armGroupLabels":55,"otherNames":56},"Assertive Outreach","The investigators will conduct weekly outreach to youths who experienced an opioid overdose and attempt to initiate treatment. Outreach is completed by a paramedic and peer coach.",[9],[57],"Community Outreach",[59],{"name":60,"affiliation":5,"role":61},"James R Langabeer, PhD","PRINCIPAL_INVESTIGATOR",[63,67],{"name":60,"role":64,"phone":65,"phoneExt":51,"email":66},"CONTACT","713-500-3925","james.r.langabeer@uth.tmc.edu",{"name":68,"role":64,"phone":69,"phoneExt":51,"email":70},"Meredith M O'Neal, MA","713-500-3624","meredith.m.oneal@uth.tmc.edu",[72],{"facility":73,"status":74,"city":75,"state":76,"zip":77,"country":78,"countryCode":79,"cosmosGeoPoint":80,"geoPoint":85,"contacts":86},"The University of Texas Health Science Center at Houston","RECRUITING","Houston","Texas","77030","United States","US",{"type":81,"coordinates":82},"Point",[83,84],-95.36327,29.76328,{"lat":84,"lon":83},[87],{"name":60,"role":64,"phone":65,"phoneExt":51,"email":66},{"type":61,"investigatorFullName":89,"investigatorTitle":90,"investigatorAffiliation":5,"oldNameTitle":51,"oldOrganization":51},"James Langabeer","Professor","100424754","phase-4-young-houston-emergency-opioid-engagement-system-100424754",false,"NCT04811014","Young Houston Emergency Opioid Engagement System","Houston Emergency Engagement System for Youths and Adolescents","YHEROES","Inclusion Criteria:\n\n* In otherwise good health based on physician assessment and medical history\n* Drug screen positive for opioids\n* Patients express a willingness to stop opioid use\n* Meet Diagnostic and Statistical Manual of Mental Disorders - Text Revision (DSM-IV-TR) criteria for opioid dependence\n* Patients must be able to speak English\n* Be agreeable to and capable of signing the informed consent and assent (parent or guardian must consent, minor must assent)\n\nExclusion Criteria:\n\n* Non-English-speaking patients\n* Have a known sensitivity to buprenorphine or naloxone\n* Be physiologically dependent on alcohol, benzodiazepines, or other drugs of abuse that require immediate medical attention. Other substance use diagnoses are not exclusionary.\n* Have a medical condition that would, in the opinion of the study physician, make participation medically hazardous, including unstable cardiovascular disease, neurological deficits, trauma, acute hepatitis, stroke, and liver or renal disease)\n* Be acutely psychotic, severely depressed, and in need of inpatient treatment, or is an immediate suicide risk\n* Be a nursing or pregnant female","ALL","13 Years","17 Years",{"count":103,"type":104},250,"ESTIMATED","INTERVENTIONAL",[107],"PHASE4","The Houston Emergency Response Opioid Engagement System for Youths and Adolescents (Young HEROES) is a community-based research program integrating assertive outreach, medication for opioid use disorder (MOUD), behavioral counseling, and peer recovery support. The objective is to compare differences in engagement and retention in treatment for individuals with opioid use disorder. The investigators also intend to understand the prevalence of opioid overdoses and OUD among youth in Houston.",[110,111,112,113,114],"Opioid-use Disorder","Opioid Dependence","Opioid Overdose","Opioid Use","Substance Use Disorders","2025-09-26",{"date":117,"type":118},"2025-10-01","ACTUAL",{"date":120,"type":118},"2021-04-19",{"date":122,"type":104},"2030-08-31",{"name":5,"class":6},1]