[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637528":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":46,"centralContacts":50,"locations":51,"responsibleParty":70,"collaborators":73,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":50,"enrollmentInfo":89,"targetDuration":50,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":101,"overallStatus":107,"whyStopped":50,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"OHSU Knight Cancer Institute","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm I (IMMEDIATE functional resistance training program)","EXPERIMENTAL","Participants join a live, online supervised group functional resistance training session, three times per week, over 45 minutes, for 16 weeks. Participants will receive exercise equipment delivered to their home and perform functional exercises that correspond to movement patterns used in everyday activities (Chair Stand, Lateral walk, Step-up, Heel-toe Raise, Plank, Push-up, 1-arm row with chair, single-arm Bicep Curl, and single-arm Tricep Extension). The 16-week program is a progressive, low-to-moderate intensity training program with a planned progression that increases the volume of training (intensity and duration (sets and reps)) gradually over time, beginning with a low volume of training. Exercise dose can be modified per the participants' tolerance to each individual exercise, and participants will be monitored throughout the trial for this purpose. Caregivers may be present for participants that require additional assistance.",[13],"Other: Functional Resistance Training",{"label":15,"type":16,"description":17,"interventionNames":18},"Arm II (IMMEDIATE stretching program)","PLACEBO_COMPARATOR","Participants join a live, online supervised group stretching and relaxation training session for 45 minutes, three times per week, for 16 weeks. During the stretching class, participants will perform a series of whole-body flexibility and mobility exercises with a final 15-minute relaxation period (i.e., progressive neuromuscular relaxation, focused breathing). Stretching exercises will be performed according to the ACSM guidelines for flexibility exercise, and from a seated position in order to minimize weight-bearing forces that might increase muscle strength or mass, and to better accommodate participants who may be unable to get down to and up from the floor.",[19],"Other: Stretching",{"label":21,"type":6,"description":22,"interventionNames":23},"Arm III (DELAYED functional resistance training program)","Participants do not participate in a group exercise class for 16 weeks and will instead be provided with basic educational information about healthy lifestyle behaviors, and monthly check-in calls from study staff. After 16 weeks, they will be invited to participate in the same 16-week functional resistance training program as Arm I.",[24],"Other: Delayed Functional Resistance Training",[26,34,40],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"Functional Resistance Training","Participants attend live, online supervised group functional resistance training sessions of low-to-moderate intensity exercises, three times per week, 45 minutes per session for 16 weeks.",[9],[31,32,33],"Strength Training","Exercise","Progressive Functional Resistance Training (PFRT)",{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":38},"Stretching","Participants attend live, online supervised group stretching and relaxation training sessions three times per week, 45 minutes per session for 16 weeks.",[15],[39],"Functional Mobility",{"type":6,"name":41,"description":42,"armGroupLabels":43,"otherNames":44},"Delayed Functional Resistance Training","Participants will receive educational information about healthy lifestyle behaviors and receive monthly check in calls from study staff. After 16 weeks, participants attend live, online supervised group functional resistance training sessions of low-to-moderate intensity exercises, three times per week, 45 minutes per session for 16 weeks.",[21],[45],"Waitlist Control",[47],{"name":48,"affiliation":5,"role":49},"Kerri Winters-Stone, Ph.D.","PRINCIPAL_INVESTIGATOR",null,[52],{"facility":5,"status":50,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"Portland","Oregon","97239","United States","US",{"type":59,"coordinates":60},"Point",[61,62],-122.67621,45.52345,{"lat":62,"lon":61},[65,69],{"name":48,"role":66,"phone":67,"phoneExt":50,"email":68},"CONTACT","503-494-0813","wintersk@ohsu.edu",{"name":48,"role":49,"phone":50,"phoneExt":50,"email":50},{"type":49,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":50,"oldOrganization":50},"Kerri Winters","Principal Investigator",[74,77],{"name":75,"class":76},"National Cancer Institute (NCI)","NIH",{"name":78,"class":6},"Oregon Health and Science University","100637528","phase-i-randomized-controlled-trial-of-functional-resistance-training-in-older-cancer-survivors-the-aces-trial-100637528",false,"NCT07606313","Phase I Randomized Controlled Trial of Functional Resistance Training in Older Cancer Survivors: The ACES Trial","ACES: Advancing Capacity to Integrate Exercise Into the Care of Older Cancer Survivors","ACES","Inclusion Criteria:\n\n* Age 65 years of age or older\n* Diagnosed with stage I-IV cancer =\\\u003C 5 years ago\n* Completed surgery, chemotherapy, or radiation therapy \\> 3 months ago (concurrent maintenance therapy, such as hormone therapy for breast or prostate cancer, is permissible)\n* Self-report at least one limitation in Activities of Daily Living (ADLs) OR at clinical risk of developing ADL impairment as evidenced by a 3-meter timed-up-and-go time \\> 13.5 seconds or 5-time chair stand time \\> 12 seconds\n* Able to ambulate independently; reliance on assistive devices other than a wheelchair is allowed\n* Currently underactive (an average of \\\u003C 30 minutes of moderate-vigorous intensity exercise 3 days\u002Fweek over the past four weeks)\n* Willing to be randomized into any of the three study arms and attend 80% or more of planned exercise sessions\n* Home internet sufficient for videoconferencing\n\nExclusion Criteria:\n\n* Contraindication to moderate intensity exercise\n* Health or medical condition that affects movement or neurological disorder, or medication that contraindicates participation in live remote resistance exercise\n* Cognitive impairment consistent with moderate dementia (confirmed by a Montreal Cognitive Assessment (MoCA) score \\\u003C 14). Cognitive impairment consistent with early-stage dementia (a MoCA score of \\\u003C20) unless a research partner (e.g., family member, caregiver, close friend) can also be consented and can assist in answering the survey questions, participating in the performance tests, or giving informed consent.\n* Not fluent in English and therefore incapable of answering survey questions, following directions during exercise or performance testing, and providing informed consent in English","ALL","65 Years",{"count":90,"type":91},150,"ESTIMATED","INTERVENTIONAL",[94],"NA","The study will assess the feasibility and preliminary efficacy of live, online supervised group functional resistance training in older cancer survivors who may have difficulty with independent functioning. The study design is a three-arm parallel group randomized controlled trial (immediate resistance training, delayed resistance training, stretching placebo) in 150 older cancer survivors. The resistance training program will be compared to two different types of common control groups: a stretching placebo group and a delayed intervention group. By using two control conditions, this study can also inform the design of future randomized trials on the selection of an appropriate control group.",[97,98,99,100],"Hematopoietic and Lymphatic System Neoplasm","Malignant Solid Neoplasm","Cancer","Functional Limitation",[99,32,102,103,104,105,106],"Cancer survivor","Functional limitation","Clinical trial","Older adult","Feasibility","NOT_YET_RECRUITING","2026-05-21",{"date":110,"type":111},"2026-05-26","ACTUAL",{"date":113,"type":91},"2026-05-18",{"date":115,"type":91},"2028-08-31",{"name":5,"class":6},1]