[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100505002":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":24,"centralContacts":28,"locations":35,"responsibleParty":54,"collaborators":56,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":23,"eligibilityCriteria":67,"healthyVolunteers":64,"sex":68,"minAge":69,"maxAge":23,"enrollmentInfo":70,"targetDuration":23,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":23,"overallStatus":37,"whyStopped":23,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Centre for Addiction and Mental Health","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Alcohol Use Disorder","Participants will be treated with 12 weeks of CBT for AUD (group therapy) and have the option to receive evidence-based pharmacotherapy for AUD guided by a pharmacotherapy algorithm.",[12],"Behavioral: CBT",{"label":14,"type":6,"description":15,"interventionNames":16},"Cannabis Use Disorder","Participants will be treated with 12 weeks of CBT + motivational enhancement therapy for CUD (group therapy).",[12],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"BEHAVIORAL","CBT","12 weeks of group CBT for AUD or CUD",[9,14],null,[25],{"name":26,"affiliation":5,"role":27},"Matthew Sloan, MD","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Kelly Xiao, MSc","CONTACT","416-535-8501","32447","Kelly.Xiao@camh.ca",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Toronto","Ontario","M6J 1H4","Canada","CA",{"type":44,"coordinates":45},"Point",[46,47],-79.39864,43.70643,{"lat":47,"lon":46},[50,53],{"name":51,"role":31,"phone":32,"phoneExt":33,"email":52},"Kelly Xiao, BSc","kelly.xiao@camh.ca",{"name":26,"role":27,"phone":23,"phoneExt":23,"email":23},{"type":55,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR",[57,60],{"name":58,"class":59},"Canadian Institutes of Health Research (CIHR)","OTHER_GOV",{"name":61,"class":6},"AFP Innovation Fund","100505002","phenotyping-patients-with-alcohol-and-cannabis-use-disorders-using-the-addictions-neuroclinical-assessment-100505002",false,"NCT05855668","Phenotyping Patients With Alcohol and Cannabis Use Disorders Using the Addictions Neuroclinical Assessment","Inclusion Criteria:\n\n1. Patient has been referred to or intends to participate in either the AUD or CUD Integrated Care Pathway (and is therefore willing to participate in group psychotherapy).\n2. Able to communicate and provide informed consent in English.\n3. 18 years of age or older.\n4. Willing and able to safely abstain from substances (other than nicotine or tobacco products), including alcohol and cannabis, for 12 hours prior to the eligibility and task-based assessments.\n5. Meets DSM-5 diagnostic criteria for AUD (AUD group) or CUD (CUD group)\n6. Meets criteria for risky drinking, defined as \\> 10 drinks per week for females and \\> 15 drinks per week for males on average over the past 30 days (AUD group) or daily or near-daily cannabis use over the past 30 days, defined as ≥ 4 days of cannabis use per week on average (CUD group)\n\nExclusion Criteria:\n\n1. Active suicidal ideation at time of assessment.\n2. Suicide attempt within the past month.\n3. Unstable psychiatric or medical status (e.g., acute psychosis or mania) or unstable use of another substance that may interfere with participation in groups (e.g. active fentanyl use).\n4. Enrollment in another study that conflicts with the procedures or scientific integrity of this study.\n5. Individuals planning to be out of the province for a substantial amount of time during the treatment period will not be permitted to enroll.","ALL","18 Years",{"count":71,"type":72},400,"ESTIMATED","INTERVENTIONAL",[75],"NA","This 2-arm study will recruit participants with 1) alcohol use disorder and 2) cannabis use disorder for a 12-week cognitive behavioral therapy, following a thorough baseline assessments on executive function, incentive salience, and negative emotionality.",[9,14],"2026-03-19",{"date":80,"type":81},"2026-03-20","ACTUAL",{"date":83,"type":81},"2022-11-10",{"date":85,"type":72},"2027-12",{"name":5,"class":6},1]