[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573521":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":27,"locations":35,"responsibleParty":64,"collaborators":67,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":19,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":19,"enrollmentInfo":80,"targetDuration":19,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":38,"whyStopped":19,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"The University of Texas Health Science Center at San Antonio","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"In Lab alcohol consumption followed by 10 days of abstinence and then 28-days naturalistic drinking","EXPERIMENTAL","Up to 40 Healthy volunteers will consume alcohol in the lab designed to produce a peak blood alcohol concentration of 0.06% and have blood collected over 6 hours. Followed by 10 days of abstinence and 4 visits to provide 1 blood sample each time. These 40 participants will then consume alcohol as usual outside the laboratory for 28 days and blood will be collected weekly (Day 0, Day 7, Day 14, 21 and 28). A second cohort of 40 participants will then undergo the naturalistic portion with blood collected on Days 0, Day 7, Day 14, 21 and 28.",[13],"Other: Alcohol (Ethanol)",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Alcohol (Ethanol)","Alcohol will be administered to participants by research staff. In Phase 1, participants will consume alcohol designed to produce a targeted blood alcohol concentration (BAC) of 0.06% using the modified Widmark equation.",[9],null,[21,24],{"name":22,"affiliation":5,"role":23},"Nathalie Hill-Kapturczak, PhD","PRINCIPAL_INVESTIGATOR",{"name":25,"affiliation":26,"role":23},"Donald Dougherty, PhD","University of North Texas Health Science Center",[28,32],{"name":22,"role":29,"phone":30,"phoneExt":19,"email":31},"CONTACT","210-567-2725","Hillkapturcz@uthscsa.edu",{"name":25,"role":29,"phone":33,"phoneExt":19,"email":34},"940-565-2649","Donald.Dougherty@unt.edu",[36,52],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"University of North Texas","RECRUITING","Denton","Texas","76201","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-97.13307,33.21484,{"lat":48,"lon":47},[51],{"name":25,"role":29,"phone":33,"phoneExt":19,"email":34},{"facility":53,"status":38,"city":54,"state":40,"zip":55,"country":42,"countryCode":43,"cosmosGeoPoint":56,"geoPoint":60,"contacts":61},"University of Texas Health Science Center San Antonio","San Antonio","78229",{"type":45,"coordinates":57},[58,59],-98.49363,29.42412,{"lat":59,"lon":58},[62],{"name":22,"role":29,"phone":30,"phoneExt":19,"email":63},"hillkapturcz@uthscsa.edu",{"type":23,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Nathalie Hill-Kapturczak","Associate Professor",[68],{"name":69,"class":70},"National Institute on Alcohol Abuse and Alcoholism (NIAAA)","NIH","100573521","phosphatidylethanol-and-other-ethanol-consumption-markers-100573521",false,"NCT06747364","Phosphatidylethanol and Other Ethanol Consumption Markers","Inclusion Criteria:\n\n1. are ≥ 21 years old;\n2. are height and weight proportionate (body mass index 18-30); and\n3. report drinking on \\> 1 days in the last month, with at least one day equal to at least achieving \\~0.06% BAC.\n\nExclusion Criteria:\n\n1. have significant current or predicted alcohol withdrawal symptoms (CIWA-AR scores ≥ 10);\n2. are currently in alcohol treatment;\n3. have substance use disorder (except nicotine, and\u002For caffeine);\n4. have a medical condition that would contraindicate participation (a positive urine pregnancy test, self-reported scheduled surgery or liver disease);\n5. are currently breast feeding;\n6. have a presence of a DSM-5 psychiatric disorder with symptoms of psychosis and\u002For delirium; or\n7. are unable to comprehend the informed consent process or study instructions.",true,"ALL","21 Years",{"count":81,"type":82},80,"ESTIMATED","INTERVENTIONAL",[85],"NA","This study is intended to help the investigators understand how a biomarker found in the blood may be used to better identify the quantity and different patterns of alcohol use.\n\nThe investigators hope that the results of this study will help identify the uses of alcohol-use markers in the blood in future alcohol prevention and treatment programs. It is hoped that the information learned from this study will benefit other people in the future.\n\nThe study participants will come into the lab and will (1) consume alcohol in the lab designed to produce a peak blood alcohol concentration of 0.06% and have blood collected over 6 hours followed by abstinence for 10 days to give a small blood sample 4 times and (2) to give a small amount of blood 5 times within 28 days (naturalistic drinking) and provide answers about alcohol use.",[88,89],"Healthy Volunteer","Alcohol Consumption",[91,92],"Healthy adult","Light, moderate and heavy drinkers","2025-05-07",{"date":95,"type":96},"2025-05-13","ACTUAL",{"date":98,"type":96},"2025-01-07",{"date":100,"type":82},"2029-06",{"name":5,"class":6},2]