[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588284":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":10,"centralContacts":29,"locations":38,"responsibleParty":53,"collaborators":57,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":10,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":10,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":81,"whyStopped":10,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Zhejiang Provincial People's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control",null,"GBM patients recevied traditional treatment options (including surgery combined with radiotherapy and chemotherapy)",[13],"Procedure: GBM patients recevied traditional treatment options",{"label":15,"type":10,"description":16,"interventionNames":17},"Treatment","GBM patients recevied surgical combination photodynamic therapy",[18],"Procedure: Photodynamic therapy (PDT)",[20,26],{"type":21,"name":22,"description":16,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Photodynamic therapy (PDT)",[15],[25],"Surgical combination photodynamic therapy",{"type":21,"name":27,"description":11,"armGroupLabels":28,"otherNames":10},"GBM patients recevied traditional treatment options",[9],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":33,"email":34},"Shaoshan Hu, Doctor","CONTACT","0571-85893451","shaoshanhu@163.com",{"name":36,"role":32,"phone":33,"phoneExt":10,"email":37},"Yi Yuan, Doctor","zjsrmyykyb@163.com",[39],{"facility":5,"status":10,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Hangzhou","Zhejiang","310014","China","CN",{"type":46,"coordinates":47},"Point",[48,49],120.16142,30.29365,{"lat":49,"lon":48},[52],{"name":36,"role":32,"phone":33,"phoneExt":10,"email":37},{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Hushaoshan","Head of neurosurgery department",[58],{"name":59,"class":6},"The Second Affiliated Hospital of Harbin Medical University","100588284","photodynamic-therapy-for-glioblastoma-multiforme-based-on-metaverse-and-yellow-fluorescence-100588284",false,"NCT06939400","Photodynamic Therapy for Glioblastoma Multiforme Based on Metaverse and Yellow Fluorescence","Study on Precision Photodynamic Therapy for Glioblastoma Multiforme Based on Metaverse and Yellow Fluorescence","Inclusion Criteria:\n\nPathologically confirmed primary focal GBM; Recurrent GBM(single or satellite lesions); Multiple (multiple germinal centers)GBM.\n\nExclusion Criteria:\n\n* Photosensitizer allergy.\n\n  * Severe coagulation disorder.\n\n    * Patients with severe cardiovascular and cerebrovascular diseases, especially patients in the acute stage.\n\n      * Multiple organ failure, end-stage patients. ⑤ Pregnant women: Photofrin is considered a class C pregnancy risk (toxic, non-teratogenic) drug with non-dialysis properties.\n\nNon-gbm diagnosis: Patients with other types of brain tumors or diseases. 7 Do not agree to informed consent: patients who are unwilling to sign informed consent or do not agree to participate in the study.","ALL","18 Years",{"count":70,"type":71},100,"ESTIMATED","OBSERVATIONAL","GBM patients receiving PDT treatment (50 cases，surgery combined with photodynamic therapy) and traditional treatment (50 cases，traditional surgery) in our hospital and partner hospitals were collected. The prognosis was analyzed by comparing with the control group from multiple perspectives such as image evaluation, imaging effect, Karnofsky score, median survival time and survival rate.",[75],"Glioblastoma Multiforme (GBM)",[77,78,79,80],"Glioblastoma Multiforme","photodynamic therapy","metaverse","yellow fluorescence","NOT_YET_RECRUITING","2025-04-14",{"date":84,"type":85},"2025-04-22","ACTUAL",{"date":87,"type":71},"2025-06-01",{"date":89,"type":71},"2027-12-31",{"name":5,"class":6},1]