[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572968":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":38,"responsibleParty":78,"collaborators":80,"id":84,"slug":85,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":92,"sex":93,"minAge":94,"maxAge":18,"enrollmentInfo":95,"targetDuration":18,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":116,"overallStatus":63,"whyStopped":18,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":131},{"fullName":5,"class":6},"University of North Carolina, Chapel Hill","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PACE Program","EXPERIMENTAL","The 16-week intervention includes: (1) a weekly group fitness class for adults with ID, (2) web-based training and resources for coaches and exercise professionals; (3) weekly coaching meetings for coaches and adults with ID, and (4) daily\u002Fweekly interactions with the PACE interactive web-based dashboard for adults with ID.",[13],"Behavioral: PACE Program",{"label":15,"type":16,"description":17,"interventionNames":18},"Waitlist Control","NO_INTERVENTION","Participants assigned to the Waitlist Control Group will not receive any intervention during this interval. Participants will receive the PACE Program after the completion of the 16-weeks for the Intervention Group.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"BEHAVIORAL","The PACE program is a 16-week inclusive exercise program taught and adapted by certified Inclusive Fitness Specialists. Study participants, called athletes, will engage in the fitness class with non-study participants with and without disabilities. Athlete participants will also meet weekly with their coaches (also study participants) to discuss goal setting and interact with the web-based dashboard.",[9],[25],{"name":26,"affiliation":5,"role":27},"Brianne R Tomaszewski, PhD., MPH","PRINCIPAL_INVESTIGATOR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},"Brianne R Tomaszewski, PhD, MPH","CONTACT","919-962-8563","Brianne_Tomaszewski@med.unc.edu",{"name":35,"role":31,"phone":36,"phoneExt":18,"email":37},"Kara Hume, PhD","919-843-2291","kara.hume@unc.edu",[39,61],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"University of Arkansas","NOT_YET_RECRUITING","Fayetteville","Arkansas","72701","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-94.15743,36.06258,{"lat":51,"lon":50},[54,58,59],{"name":55,"role":31,"phone":56,"phoneExt":18,"email":57},"Melissa N Savage, PhD","479-575-4209","mns029@uark.edu",{"name":35,"role":31,"phone":36,"phoneExt":18,"email":37},{"name":55,"role":60,"phone":18,"phoneExt":18,"email":18},"SUB_INVESTIGATOR",{"facility":62,"status":63,"city":64,"state":65,"zip":66,"country":45,"countryCode":46,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"University of North Carolina","RECRUITING","Chapel Hill","North Carolina","27517",{"type":48,"coordinates":68},[69,70],-79.05584,35.9132,{"lat":70,"lon":69},[73,75,77],{"name":74,"role":31,"phone":32,"phoneExt":18,"email":33},"Brianne R Tomaszewski, Ph.D., MPH",{"name":76,"role":31,"phone":36,"phoneExt":18,"email":37},"Kara Hume, Ph.D.",{"name":74,"role":27,"phone":18,"phoneExt":18,"email":18},{"type":79,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[81],{"name":82,"class":83},"National Institute on Aging (NIA)","NIH","100572968","physical-activity-and-community-empowerment-project-100572968",false,"NCT06740162","Physical Activity and Community EmPOWERment Project","A Stage 1 Pilot Test for Feasibility and Efficacy of a Multi-Level Intervention to Increase Physical Activity in Adults With Intellectual Disability: Physical Activity and Community EmPOWERment (PACE)","PACE","Inclusion criteria for adults with ID will include:\n\n* ages 18 and older with a prior clinical diagnosis of ID, confirmed by scores \\\u003C 70 and + 90% on the Leiter-3 International Performance Scales and\u002For an adaptive behavior measure using the Vineland Adaptive Behavior Scales,\n* Medical clearance to participate in moderate-to-vigorous physical activity as determined by the American College of Sports Medicine (ACSM) preparticipation algorithm,\n* Adult does not show clinically elevated symptoms of Alzheimer's Disease (AD)\u002F Alzheimer's Disease and Related Dementias (ADRD) as indicated by a score of \\\u003C 20 on the Dementia Screening Questionnaire for Individuals with Intellectual Disabilities.\n* One caregiver\u002Fguardian is able and willing to participate.\n* must tolerate at least 8 hours of daily wear-time of Actigraph device during initial assessment period (4 of 7 days),\n* must average 20 minutes or less of moderate to vigorous physical activity (MVPA) minutes per day (140 MVPA minutes or less across 7-day period measured during the initial assessment period, and\n* must reside in North Carolina or Arkansas.\n\nExclusion Criteria for adults with ID:\n\n• Diagnosis of AD, dementia, or related disorders. Participants will not be excluded based on gender, race, or ethnicity. There will be no upper age limit due to the heterogeneity of onset of AD\u002FADRD in individuals with ID.\n\nInclusion criteria for coach will include:\n\n* access to the internet and a mobile device,\n* has weekly contact with the adult participant with ID,\n* can converse and read in English to comprehend intervention materials and website content, and\n* must reside in North Carolina or Arkansas\n\nInclusion criteria for caregiver will include:\n\n* ability to converse and read in English to comprehend and answer interview questions, (2) must care for an adult with ID who is willing to participate in the study,\n* must reside in North Carolina or Arkansas, and\n* must attend all study visits with adult with ID.",true,"ALL","18 Years",{"count":96,"type":97},376,"ESTIMATED","INTERVENTIONAL",[100],"NA","Purpose: Conduct a wait-list randomized controlled trial (RCT) of an inclusive physical activity program called PACE for adults with intellectual disability (ID) who are not yet showing signs of Alzheimer's Disease (AD)\u002Fage-related dementias (ARD).\n\nParticipants: Participants include 120 adults with ID, their caregivers, and their coaches (up to 360 individual participants, grouped as triads), recruited through the University of North Carolina at Chapel Hill and the University of Arkansas. Participants also include 16 exercise professionals.\n\nProcedures (methods): Each cohort will include 20 triads who are randomly assigned to the PACE program or the waitlist control group.",[103,104,105,106,107,108,109,110,111,112,113,114,115],"Intellectual Disability","Neurodevelopmental Disorders","Autism Spectrum Disorder","Down Syndrome","Fragile X Syndrome","Cri-du-Chat Syndrome","De Lange Syndrome","Mental Retardation, X-Linked","Prader-Willi Syndrome","Rubinstein-Taybi Syndrome","Trisomy 13 Syndrome","WAGR Syndrome","Williams Syndrome",[117,118,119,120,121],"physical activity","intellectual disability","age-associated memory impairment","aging","Alzheimer Disease prevention","2026-02-19",{"date":124,"type":125},"2026-02-23","ACTUAL",{"date":127,"type":125},"2025-01-10",{"date":129,"type":97},"2028-06",{"name":5,"class":6},2]