[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100540605":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":33,"centralContacts":37,"locations":45,"responsibleParty":63,"collaborators":26,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":26,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":26,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"East Carolina University","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"AE Group","EXPERIMENTAL","The AE group will exercise on aerobic machines (i.e. treadmill, elliptical, bicycle)\n\nAll exercise participants will be prescribed exercise that meets guidelines of the American College of Obstetricians and Gynecologists (ACOG), American College of Sports Medicine (ACSM), and the American Heart Association (AHA); 150 minutes per week, moderate intensity (60-80% aerobic capacity, Rating of Perceived Exertion, RPE, 12-15) per week. These limits are the same as those that generated previous positive findings for our preliminary data.",[13],"Behavioral: Exercise Modes",{"label":15,"type":10,"description":16,"interventionNames":17},"RE Group","The RE group will perform 12-15 repetitions of 10-12 resistance exercises in a circuit, for 3 sets, with a rest period of 30-60 seconds between sets as needed.\\[172\\] Seated isokinetic exercise using resistance machines will target all major muscle groups. Light dumbbells and resistance bands will be used if the participant is unable to lift the minimal load on machines. Core exercises will be performed at the end of the session (i.e. seated side bends)\n\nAll exercise participants will be prescribed exercise that meets guidelines of the American College of Obstetricians and Gynecologists (ACOG), American College of Sports Medicine (ACSM), and the American Heart Association (AHA); 150 minutes per week, moderate intensity (60-80% aerobic capacity, Rating of Perceived Exertion, RPE, 12-15) per week. These limits are the same as those that generated previous positive findings for our preliminary data.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"AERE Group","AERE group will alternate between AE exercise and RE; for this group, RE exercises will consist of 1 set of 12-15 repetitions of 4 resistance exercises, then 5 minutes of AE, then repeat this cycle with different exercises.\n\nAll exercise participants will be prescribed exercise that meets guidelines of the American College of Obstetricians and Gynecologists (ACOG), American College of Sports Medicine (ACSM), and the American Heart Association (AHA); 150 minutes per week, moderate intensity (60-80% aerobic capacity, Rating of Perceived Exertion, RPE, 12-15) per week. These limits are the same as those that generated previous positive findings for our preliminary data.",[13],{"label":23,"type":24,"description":25,"interventionNames":26},"Control","NO_INTERVENTION","The Control group will participate in weekly sessions that focus on stretching, breathing, and healthy lifestyle.",null,[28],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":26},"BEHAVIORAL","Exercise Modes","Moderate intensity aerobic exercise Moderate intensity resistance exercise Moderate intensity combination exercise",[9,19,15],[34],{"name":35,"affiliation":5,"role":36},"Linda E May, MS, PhD","PRINCIPAL_INVESTIGATOR",[38,42],{"name":35,"role":39,"phone":40,"phoneExt":26,"email":41},"CONTACT","2527377072","mayl@ecu.edu",{"name":43,"role":39,"phone":26,"phoneExt":26,"email":44},"James DeVente, MD","deventeja@ecu.edu",[46],{"facility":5,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RECRUITING","Greenville","North Carolina","27834","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-77.36635,35.61266,{"lat":57,"lon":56},[60,62],{"name":35,"role":39,"phone":61,"phoneExt":26,"email":41},"252-737-7072",{"name":43,"role":39,"phone":26,"phoneExt":26,"email":44},{"type":36,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Linda May","Principal Investigator","100540605","physical-activity-to-mitigate-preeclampsia-risk-100540605",false,"NCT06319014","Physical Activity to Mitigate PreEclampsia Risk","Physical Activity to Mitigate PreEclampsia Risk (PAMPER)","PAMPER","Inclusion Criteria:\n\n* healthy women, age 18-40 years, \\\u003C16 weeks' gestation, with singleton pregnancy; women (BMI:18.5-45.0), sedentary, cleared by their obstetric provider.\n\nExclusion Criteria:\n\n* pre-existing chronic conditions such as HIV, lupus, etc.; taking medicines that affect fetal development; and\u002For lack of telephone or email contact information).",true,"FEMALE","18 Years","40 Years",{"count":79,"type":80},224,"ESTIMATED","INTERVENTIONAL",[83],"NA","The purpose of this study is to compare the effects of aerobic (AE), resistance (RE), and combination (AERE) exercise throughout pregnancy on selected maternal and fetal\u002Fneonatal physiological variables in women at-risk for preeclampsia. The central hypothesis of this project is that exercise will decrease severity and occurrence of preeclampsia symptoms, thus improving maternal, pregnancy, and birth outcomes.\n\nAim 1. Determine the influence of different exercise modes during pregnancy at risk of preeclampsia on maternal cardiometabolic health.\n\nAim 2. Determine the most effective exercise mode in pregnancy at risk of preeclampsia on improving birth and infant health outcomes.",[86],"Pre-Eclampsia","2024-06-28",{"date":89,"type":90},"2024-07-01","ACTUAL",{"date":92,"type":90},"2024-06-24",{"date":94,"type":80},"2026-10-01",{"name":5,"class":6},1]