[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616403":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":30,"locations":36,"responsibleParty":50,"collaborators":11,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":56,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":11,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":80,"whyStopped":11,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"University Hospital, Geneva","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Stardard Mentalization-Based Treatment","ACTIVE_COMPARATOR",null,[13],"Other: Standard Mentalization-Based Treatment",{"label":15,"type":16,"description":11,"interventionNames":17},"Trauma-Focused Mentalization-Based Treatment","EXPERIMENTAL",[18],"Other: Trauma-Focused Mentalization-Based Treatment",[20,27],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Standard Mentalization-Based Treatment","Standard MBT treatment, specialized and validated treatment for BPD, which consists of weekly group and individual sessions for one year without any trauma focus, will serve as a comparison.",[9],[25,26],"TAU (Treatment As Usual)","Standard MBT",{"type":6,"name":15,"description":28,"armGroupLabels":29,"otherNames":11},"The intervention will be a trauma-focused Mentalization-based treatment (MBT-TF), consisting of a 3-phase group intervention with an individual component (weekly sessions) offered as needed, focused psychoeducation about post-traumatic stress symptoms and on improving trauma related mentalizing abilities and interpersonal functioning over a 12-month period (45-50 sessions in total).",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":11,"email":35},"Eva Rüfenacht, MD","CONTACT","+41223054552","EvaNina.Rufenacht@hug.ch",[37],{"facility":38,"status":11,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":11},"University Hospitals of Geneva","Geneva","Canton of Geneva","1205","Switzerland","CH",{"type":45,"coordinates":46},"Point",[47,48],6.14569,46.20222,{"lat":48,"lon":47},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"SPONSOR_INVESTIGATOR","Eva Rüfenacht","Senior Physician, Head of the Emotion Regulation Disorders Unit , Principal Investigator","100616403","pilot-study-for-the-evaluation-of-a-new-psychotherapeutic-treatment-for-borderline-personality-disorder-patients-with-post-traumatic-stress-symptoms-100616403",false,"NCT07305155","Pilot Study for the Evaluation of a New Psychotherapeutic Treatment for Borderline Personality Disorder Patients With Post-traumatic Stress Symptoms","A Feasibility Randomized-controlled Trial Comparing Trauma-focused Mentalization Based Treatment With Standard Mentalization-based Treatment in Patients Presenting With Complex Post-traumatic Stress and Borderline Personality Disorder","MBT-TF","Inclusion Criteria:\n\n* Age between 18 and 65 years.\n* Meeting ≥4 of 9 SCID-5 PD criteria associated with functional impairment (either subthreshold or full BPD diagnosis), and an LPFS-BF 2.0 score ≥31 (≥1.5 standard deviations above the latent mean, T-score ≥65), indicating moderate to severe personality disorder features.\n* Diagnosis of CPTSD according to ICD-11 criteria, confirmed via ITQ with clinical checks.\n\nExclusion Criteria:\n\n* Mental disability.\n* Severe psychiatric psychopathology requiring immediate treatment (e.g., BMI \\\u003C16.5, acute bipolar episode, current psychosis).\n* Severe active substance dependence.\n* Severe physical health problems (e.g., severe cardiovascular conditions). Severe neurological disorder.","ALL","18 Years","65 Years",{"count":66,"type":67},40,"ESTIMATED","INTERVENTIONAL",[70],"NA","Borderline Personality Disorder (BPD) is a serious mental health condition that often co-occurs with Complex PTSD (CPTSD), making treatment more challenging. Trauma-Focused Mentalization-Based Treatment (MBT-TF) is a new adaptation of standard MBT designed for individuals with high trauma exposure. Early findings are promising, but further research is needed. This study at Geneva University Hospitals (HUG) will test the feasibility and acceptability of MBT-TF compared with standard MBT, gathering feedback from patients and clinicians and laying the groundwork for a larger clinical trial.",[73,74],"Borderline Personality Disorder (BPD)","PTSD - Post Traumatic Stress Disorder",[76,77,78,79],"Borderline Personality Disorder","Post Traumatic Stress Disorder","Mentalization-based treatment","trauma-focused mentalization-based treatment","NOT_YET_RECRUITING","2026-02-04",{"date":83,"type":84},"2026-02-06","ACTUAL",{"date":86,"type":67},"2026-06-01",{"date":88,"type":67},"2030-12",{"name":52,"class":6},1]