[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625935":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":57,"collaborators":59,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":65,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":10,"studyType":77,"phases":10,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":87,"whyStopped":10,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Igenomix","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Discarded blastocysts",null,"All study participants will follow the same procedure. Study participation is limited to informed consent signature and donation of the clinically discarded embryos. Participants will not undergo any other study-specific procedures.",[13],"Genetic: Multiomics analysis",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"GENETIC","Multiomics analysis","Donated discarded blastocysts (day 5\u002F6) will undergo 2 TE biopsies and 1 ICM biopsy which will be analyzed for chromosomic status and multiomics profiles. Additional, when possible, cumulus cells and sper cells will also be analyzed.\n\nAfter donation of the discarded embryos, participants will follow their established IVF treatment.",[9],[21],{"name":22,"affiliation":23,"role":24},"Carmen Rubio, PhD","Vicepresident R&D Genetic Services","STUDY_CHAIR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Carlos Gómez De La Cruz, PhD","CONTACT","(+34) 963905310","carlos.gomez@vitrolifegroup.com",{"name":32,"role":28,"phone":10,"phoneExt":10,"email":33},"Esperanza Irles Vidal, PhD","esperanza.irles@vitrolifegroup.com",[35],{"facility":36,"status":10,"city":37,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Oslo University Hospital HF (OUS HF), Rikshospitalet","Oslo","0372","Norway","NO",{"type":42,"coordinates":43},"Point",[44,45],10.74609,59.91273,{"lat":45,"lon":44},[48,52,55],{"name":49,"role":28,"phone":50,"phoneExt":10,"email":51},"Maria Biba, PhD","(+47) 94816156","marbib@ous-hf.no",{"name":53,"role":28,"phone":10,"phoneExt":10,"email":54},"Maria Vera, PhD","mavrod@ous-hf.no",{"name":49,"role":56,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":58,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[60],{"name":61,"class":62},"Oslo University Hospital","OTHER","100625935","pilot-study-of-discarded-blastocysts-100625935",false,"NCT07429097","Pilot Study of Discarded Blastocysts","Prospective Observational Pilot Study of Discarded Blastocysts: a Molecular Approach to Uncovering Hidden Reproductive Potential","DECODE","Inclusion Criteria:\n\n* Patients whose written informed consent approved by the Ethic Committee has been obtained, after having been duly informed of the nature of the study and voluntarily accepted to participate after being fully aware of the potential risks, benefits, and any discomfort involved.\n* Patients undergoing regular IVF\u002FICSI cycles with fresh oocytes and embryo culture to the blastocyst stage (day 5-6 after fertilization)\n* Patients' age will be between 20-42 years of age.\n* Patients without PGT-M or PGT-SR indication.\n\nExclusion Criteria:\n\n* Patients who do not have at least one discarded blastocyst on day 5-6 of development.\n* Patients with discarded blastocysts that do not meet these criteria:\n* Presence of ICM\n* Non-degenerated","FEMALE","20 Years","42 Years",{"count":75,"type":76},150,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to determine multiomics patterns related to global embryo quality to help overcome the limitations of conventional embryo quality assessment. The main question it aims to answer is:\n\n• Do discarded blastocysts that reach the blastocyst stage (days 5-6) show characteristic multiomics profiles which correlate with chromosomal abnormalities, providing insights into embryo viability?\n\nFor that, patients undergoing an IVF treatment will be asked to donate their clinically discarded 5\u002F6-day embryos (those that do not meet clinical criteria to be used for reproductive purposes). Participation in the study will not interfere with the planned IVF treatment. Patient participation is limited to signature of the informed consent to donate embryos and no other study-specific procedures will be performed on participants.",[80],"Infertility (IVF Patients)",[82,83,84,85,86],"blastocyst","aneuploidy","inner cell mass","PGT-A","trophectoderm","NOT_YET_RECRUITING","2026-02-23",{"date":90,"type":91},"2026-02-24","ACTUAL",{"date":93,"type":76},"2026-02",{"date":95,"type":76},"2027-05",{"name":5,"class":6},1]