[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616127":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":30,"locations":37,"responsibleParty":62,"collaborators":65,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":24,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":24,"enrollmentInfo":78,"targetDuration":24,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":89,"overallStatus":93,"whyStopped":24,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"University of British Columbia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1","EXPERIMENTAL","One night of Home sleep apnea testing (HSAT) with Negative Pressure Neck Therapy (NPNT) intervention, followed by 7 night washout, then one night of HSAT only",[13],"Device: Negative Pressure Neck Therapy (NPNT)",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2","One night of HSAT only, followed by 7 night washout, then one night of HSAT with NPNT intervention.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Negative Pressure Neck Therapy (NPNT)","Negative pressure neck therapy (NPNT) is a self-contained, non-invasive, soft, flexible, external neck collar",[9,15],null,[26],{"name":27,"affiliation":28,"role":29},"John A Fleetham, MD","VCHA\u002FUBC","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":35,"email":36},"Research Manager","CONTACT","6048754111","62500","Shelley.Abercromby@vch.ca",[38,54],{"facility":39,"status":24,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Centre for Lung Health","Vancouver","British Columbia","V5Z 1M9","Canada","CA",{"type":46,"coordinates":47},"Point",[48,49],-123.11934,49.24966,{"lat":49,"lon":48},[52],{"name":24,"role":33,"phone":53,"phoneExt":24,"email":24},"6048754122",{"facility":55,"status":24,"city":40,"state":41,"zip":56,"country":43,"countryCode":44,"cosmosGeoPoint":57,"geoPoint":59,"contacts":60},"Leon Judah Blackmore Centre for Sleep Disorders","V6T 2B5",{"type":46,"coordinates":58},[48,49],{"lat":49,"lon":48},[61],{"name":24,"role":33,"phone":53,"phoneExt":24,"email":24},{"type":29,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"John Fleetham","Professor",[66],{"name":67,"class":6},"Vancouver Coastal Health Research Institute","100616127","pilot-study-of-negative-pressure-neck-therapy-npnt-100616127",false,"NCT07301567","Pilot Study of Negative Pressure Neck Therapy (NPNT)","A Proof-of-concept Pilot Study to Determine the Safety and Effectiveness of the Negative Pressure Neck Therapy (NPNT) in Healthy Participants.","Inclusion Criteria:\n\n* Body mass index ≤42 kg\u002Fm2\n* Able to speak, read, and write English\n\nExclusion Criteria:\n\n* Known sleep disorder such as Obstructive Sleep Apnea (OSA), narcolepsy, restless leg syndrome, idiopathic hypersomnolence or chronic insomnia\n* No previous surgery, injury, or radiation to the neck\n* Excessive hair or beard in the area of the neck, and\u002For unwillingness to shave that area for the duration of this study\n* Inflammatory skin condition, such as acne or eczema in the neck area\n* Known silicone allergy\n* Night shift work because of irregular sleep-wake cycles\n* Excessive alcohol intake, defined as that leading to interference with work, home life, or the ability to optimally perform normal everyday duties and tasks\n* Use of illicit drugs currently or within the past 5 years\n* Serious pulmonary disease\n* Use of home oxygen or oxygen saturation \\\u003C94%\n* Cancer that has been in remission for less than one year\n* Previous surgery for peripheral arterial disease",true,"ALL","19 Years",{"count":79,"type":80},10,"ESTIMATED","INTERVENTIONAL",[83],"NA","Obstructive sleep apnea (OSA) is a serious, chronic sleep-related breathing disease in which the upper airway repeatedly collapses during sleep, leading to intermittent oxygen deprivation. This pilot study will evaluate the Safety and Efficacy of Negative Pressure Neck Therapy (NPNT) in up to 10 healthy participants. Participants will undergo 2 separate home sleep apnea tests (HSAT) approximately 1 week apart and will be randomly assigned to wear the NPNT device at either night 1 or night 2 of HSAT. Participation will include 5 on-site visits and 1 phone call over approximately 1 month.",[86,87,88],"Obstructive Apnea","Sleep Apnea Syndrome, Obstructive","Sleep Disorder (Disorder)",[90,91,92],"sleep apnea","Obstructive sleep apnea","sleep disordered breathing","NOT_YET_RECRUITING","2025-12-10",{"date":96,"type":97},"2025-12-24","ACTUAL",{"date":99,"type":80},"2026-01",{"date":101,"type":80},"2026-12",{"name":5,"class":6},2]