[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100443779":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":60,"centralContacts":64,"locations":70,"responsibleParty":92,"collaborators":10,"id":94,"slug":95,"hasResults":96,"nctId":97,"briefTitle":98,"officialTitle":98,"acronym":10,"eligibilityCriteria":99,"healthyVolunteers":100,"sex":101,"minAge":102,"maxAge":10,"enrollmentInfo":103,"targetDuration":10,"studyType":106,"phases":10,"briefSummary":107,"conditions":108,"keywords":10,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Group I: No strong family history of pancreatic cancer",null,"Participants in Group 1 consist of BRCA, ATM and PALB2 mutation carriers without a strong family history of pancreatic cancer and can choose to undergo annual magnetic resonance imaging (MRI)\u002FMagnetic resonance cholangiopancreatography (MRCP) and EUS screening, or they may opt out of annual MRI screening. Participants also have the opportunity to co-enroll in the University of California, San Francisco (UCSF) BRCA Center Biorepository for biospecimen\u002Fbiomarker collection and will complete surveys, including the optional eGene questionnaire, which involves co-enrollment in the eGene Study.",[13,14,15,16,17],"Procedure: Biospecimen Collection","Procedure: Magnetic Resonance Cholangiopancreatography","Procedure: Magnetic Resonance Imaging","Procedure: Endoscopic ultrasound","Other: Questionnaires",{"label":19,"type":10,"description":20,"interventionNames":21},"Group II: Strong family history of pancreatic cancer","Participants in Group 2 consist of BRCA, ATM and PALB2 mutation carriers with a strong family history of pancreatic cancer. Participants may undergo annual MRI\u002FMRCP screening and may also elect to get an endoscopic ultrasound (EUS) every other year. Participants also have the opportunity to co-enroll in the UCSF BRCA Center Biorepository for biospecimen\u002Fbiomarker collection and will complete surveys, including the optional eGene questionnaire, which involves co-enrollment in the eGene Study.",[13,14,15,16,17],[23,30,36,48,54],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"PROCEDURE","Biospecimen Collection","Undergo blood, tissue, and saliva collection",[9,19],[29],"Biological Sample Collection",{"type":24,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Magnetic Resonance Cholangiopancreatography","Undergo MRCP",[9,19],[35],"MRCP",{"type":24,"name":37,"description":38,"armGroupLabels":39,"otherNames":40},"Magnetic Resonance Imaging","Undergo MRI",[9,19],[41,42,43,44,45,46,47],"Magnetic Resonance Imaging Scan","MR Imaging","MRI","MRI Scan","NMR Imaging","NMRI","Nuclear Magnetic Resonance Imaging",{"type":24,"name":49,"description":50,"armGroupLabels":51,"otherNames":52},"Endoscopic ultrasound","Undergo endoscopic ultrasound",[9,19],[53],"EUS",{"type":6,"name":55,"description":56,"armGroupLabels":57,"otherNames":58},"Questionnaires","Complete the following questionnaires: Pancreatic Cancer Knowledge Survey, Pancreatic Cancer Worry Scale, Disease Specific Perceived Risk Survey, eGene Questionnaire",[9,19],[59],"Surveys",[61],{"name":62,"affiliation":5,"role":63},"Pamela N Munster, MD","PRINCIPAL_INVESTIGATOR",[65],{"name":66,"role":67,"phone":68,"phoneExt":10,"email":69},"Phu Lam","CONTACT","(415) 353-8337","Phu.Lam@ucsf.edu",[71],{"facility":72,"status":73,"city":74,"state":75,"zip":76,"country":77,"countryCode":78,"cosmosGeoPoint":79,"geoPoint":84,"contacts":85},"University of California San Francisco","RECRUITING","San Francisco","California","94143","United States","US",{"type":80,"coordinates":81},"Point",[82,83],-122.41942,37.77493,{"lat":83,"lon":82},[86,88,91],{"name":66,"role":67,"phone":87,"phoneExt":10,"email":69},"415-353-8337",{"name":10,"role":67,"phone":89,"phoneExt":10,"email":90},"877-827-3222","cancertrials@ucsf.edu",{"name":62,"role":63,"phone":10,"phoneExt":10,"email":10},{"type":93,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100443779","pilot-study-of-pancreatic-cancer-screening-100443779",false,"NCT05058846","Pilot Study of Pancreatic Cancer Screening","Inclusion Criteria:\n\nAbility to provide consent and willing, and able to comply with study procedures Ability to read and speak English\n\nGROUP I:\n\n* Documentation of pathogenic or likely pathogenic germline BRCA 1 and 2, ATM or PALB2 germline genetic mutation\n* No strong family history of pancreatic cancer (defined as having \\>= 1 first-degree or second-degree relative with a history of pancreatic cancer)\n* Age \\>= 50 years old at time of consent.\n\nGROUP II:\n\n* Documentation of pathogenic or likely pathogenic germline BRCA 1 and 2, ATM, or PALB2 germline genetic mutation\n* Has strong family history of pancreatic cancer (defined as having \\>= 1 first-degree or second-degree relative with a history of pancreatic cancer)\n* Age \\>= 18 years old at time of consent (screening generally begins 10 years prior to the earliest pancreatic cancer in the family)\n\nExclusion Criteria:\n\n* Prior or active pancreatic cancer.\n* Pregnant women are excluded from this study because effects of an MRI on developing fetus is unknown.",true,"ALL","18 Years",{"count":104,"type":105},250,"ESTIMATED","OBSERVATIONAL","This study investigates how often abnormal findings from routine magnetic resonance imaging occur in people with genetic mutations in BReast CAncer gene. (BRCA), ataxia telangiectasia mutated gene (ATM), or PALB2 screened for pancreatic cancer. This study may lead to a greater understanding of cancer and potentially, improvements in cancer screening and treatment.",[109],"Pancreatic Carcinoma","2025-04-30",{"date":112,"type":113},"2025-05-02","ACTUAL",{"date":115,"type":113},"2022-01-20",{"date":117,"type":105},"2032-01-31",{"name":5,"class":6},1]