[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100493140":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":32,"responsibleParty":210,"collaborators":26,"id":212,"slug":213,"hasResults":214,"nctId":215,"briefTitle":216,"officialTitle":217,"acronym":218,"eligibilityCriteria":219,"healthyVolunteers":214,"sex":220,"minAge":221,"maxAge":26,"enrollmentInfo":222,"targetDuration":26,"studyType":225,"phases":226,"briefSummary":228,"conditions":229,"keywords":232,"overallStatus":35,"whyStopped":26,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":245,"locationsCount":246},{"fullName":5,"class":6},"Enspire DBS Therapy, Inc.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"DBS+Rehab","EXPERIMENTAL","Active-DBS combined with motor rehabilitation",[13],"Device: Deep Brain Stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Rehab","ACTIVE_COMPARATOR","Control-DBS combined with motor rehabilitation",[19],"Other: Rehabilitation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Deep Brain Stimulation","Deep Brain Stimulation (DBS) of the dentate nucleus area of the cerebellum plus motor rehabilitation to improve upper-extremity function.",[9],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"OTHER","Rehabilitation","Motor rehabilitation to improve upper-extremity function.",[15],[33,56,73,94,111,128,148,165,182,199],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Barrow Neurological Institute (BNI)","RECRUITING","Phoenix","Arizona","85013","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-112.07404,33.44838,{"lat":45,"lon":44},[48,53],{"name":49,"role":50,"phone":51,"phoneExt":26,"email":52},"Markey Olson, PhD","CONTACT","602-406-6055","neuromodulationresearch@commonspirit.org",{"name":54,"role":55,"phone":26,"phoneExt":26,"email":26},"Francisco Ponce, MD","PRINCIPAL_INVESTIGATOR",{"facility":57,"status":35,"city":58,"state":59,"zip":60,"country":39,"countryCode":40,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Mayo Clinic Florida","Jacksonville","Florida","32224",{"type":42,"coordinates":62},[63,64],-81.65565,30.33218,{"lat":64,"lon":63},[67,71],{"name":68,"role":50,"phone":69,"phoneExt":26,"email":70},"Amber Patchell","904-953-4711","Patchell.Amber@mayo.edu",{"name":72,"role":55,"phone":26,"phoneExt":26,"email":26},"Sanjeet Grewal, MD",{"facility":74,"status":35,"city":75,"state":76,"zip":77,"country":39,"countryCode":40,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Johns Hopkins School of Medicine","Baltimore","Maryland","21218",{"type":42,"coordinates":79},[80,81],-76.61219,39.29038,{"lat":81,"lon":80},[84,88,92],{"name":85,"role":50,"phone":86,"phoneExt":26,"email":87},"Robert Nickl, PhD","410-955-1347","rnickl1@jh.edu",{"name":89,"role":50,"phone":90,"phoneExt":26,"email":91},"Jessica Wollet","667-306-8141","jwollet1@jhu.edu",{"name":93,"role":55,"phone":26,"phoneExt":26,"email":26},"William Anderson, MD, PhD",{"facility":95,"status":35,"city":96,"state":97,"zip":98,"country":39,"countryCode":40,"cosmosGeoPoint":99,"geoPoint":103,"contacts":104},"Massachusetts General Hospital","Boston","Massachusetts","02114",{"type":42,"coordinates":100},[101,102],-71.05977,42.35843,{"lat":102,"lon":101},[105,109],{"name":106,"role":50,"phone":107,"phoneExt":26,"email":108},"Erin Donahue, PhD","617-643-3732","ekdonahue@mgh.harvard.edu",{"name":110,"role":55,"phone":26,"phoneExt":26,"email":26},"R. Mark Richardson, MD, PhD",{"facility":112,"status":35,"city":113,"state":114,"zip":115,"country":39,"countryCode":40,"cosmosGeoPoint":116,"geoPoint":120,"contacts":121},"Mayo Clinic","Rochester","Minnesota","55906",{"type":42,"coordinates":117},[118,119],-92.4699,44.02163,{"lat":119,"lon":118},[122,126],{"name":123,"role":50,"phone":124,"phoneExt":26,"email":125},"Olyvia Heaser","507-538-6563","Heaser.Olyvia@mayo.edu",{"name":127,"role":55,"phone":26,"phoneExt":26,"email":26},"Rushna Ali, MD",{"facility":129,"status":35,"city":130,"state":130,"zip":131,"country":39,"countryCode":40,"cosmosGeoPoint":132,"geoPoint":136,"contacts":137},"NYU Langone Health","New York","10016",{"type":42,"coordinates":133},[134,135],-74.00597,40.71427,{"lat":135,"lon":134},[138,142,146],{"name":139,"role":50,"phone":140,"phoneExt":26,"email":141},"Cathryn Lapierre","6465012762","cathryn.lapierre@nyulangone.org",{"name":143,"role":50,"phone":144,"phoneExt":26,"email":145},"Talia Rudy","212-263-0998","talia.rudy@nyulangone.org",{"name":147,"role":55,"phone":26,"phoneExt":26,"email":26},"Alon Mogilner, MD, PhD",{"facility":149,"status":35,"city":150,"state":151,"zip":152,"country":39,"countryCode":40,"cosmosGeoPoint":153,"geoPoint":157,"contacts":158},"Cleveland Clinic","Cleveland","Ohio","44195",{"type":42,"coordinates":154},[155,156],-81.69541,41.4995,{"lat":156,"lon":155},[159,163],{"name":160,"role":50,"phone":161,"phoneExt":26,"email":162},"Karen Stevenson","216-445-0926","STEVENK12@ccf.org",{"name":164,"role":55,"phone":26,"phoneExt":26,"email":26},"Andre Machado, MD, PhD",{"facility":166,"status":35,"city":167,"state":168,"zip":169,"country":39,"countryCode":40,"cosmosGeoPoint":170,"geoPoint":174,"contacts":175},"Thomas Jefferson University","Philadelphia","Pennsylvania","19107",{"type":42,"coordinates":171},[172,173],-75.16362,39.95238,{"lat":173,"lon":172},[176,180],{"name":177,"role":50,"phone":178,"phoneExt":26,"email":179},"Neurosurgery Research Department","215-503-4852","neurosurgeryresearch@jefferson.edu",{"name":181,"role":55,"phone":26,"phoneExt":26,"email":26},"Chengyuan Wu, MD",{"facility":183,"status":35,"city":184,"state":185,"zip":186,"country":39,"countryCode":40,"cosmosGeoPoint":187,"geoPoint":191,"contacts":192},"Rhode Island Hospital","Providence","Rhode Island","02903",{"type":42,"coordinates":188},[189,190],-71.41283,41.82399,{"lat":190,"lon":189},[193,197],{"name":194,"role":50,"phone":195,"phoneExt":26,"email":196},"Amanda Hasbrouck","401-444-6682","ahasbrouck@lifespan.org",{"name":198,"role":55,"phone":26,"phoneExt":26,"email":26},"Wael Asaad, MD, PhD",{"facility":200,"status":201,"city":202,"state":203,"zip":204,"country":39,"countryCode":40,"cosmosGeoPoint":205,"geoPoint":209,"contacts":26},"Medical University of South Carolina (MUSC)","TERMINATED","Charleston","South Carolina","29425",{"type":42,"coordinates":206},[207,208],-79.93275,32.77632,{"lat":208,"lon":207},{"type":211,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100493140","pilotpivotal-study-of-dbsrehab-after-stroke-100493140",false,"NCT05701280","Pilot\u002FPivotal Study of DBS+Rehab After Stroke","Rehab With Electrical Stimulation Therapy to Optimize Rehabilitation Effect (RESTORE): A Pivotal Study","RESTORE","Key Inclusion Criteria:\n\n* Ischemic stroke, with an initial incident occurring between 12 months to 6 years before implant, resulting in residual upper extremity hemiparesis.\n\nKey Exclusion Criteria:\n\n* Previous or subsequent cerebrovascular events resulting in residual upper extremity impairment\n* Brain lesions with significant involvement of the brainstem, cerebellum, or thalamus","ALL","21 Years",{"count":223,"type":224},202,"ESTIMATED","INTERVENTIONAL",[227],"NA","The RESTORE Stroke Study will evaluate the safety and effectiveness of DBS+Rehab for treating arm weakness and reduced function after a stroke.",[230,231],"Stroke","Upper Extremity Paresis",[233,23,234,235,29,236],"Ischemic Stroke","DBS","Physical Therapy","Brain Stimulation","2026-01-20",{"date":239,"type":240},"2026-01-21","ACTUAL",{"date":242,"type":240},"2023-02-03",{"date":244,"type":224},"2030-06",{"name":5,"class":6},10]