[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100456525":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":60,"collaborators":63,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":25,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":90,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"The University of Texas Health Science Center, Houston","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PRP Treatment","EXPERIMENTAL","PRP preparation will be injected to the myometrium around the uterine incision after closure of the first layer.",[13],"Other: Platelet Rich Plasma",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","0.9% of Normal Saline will be injected to the myometrium around the uterine incision after closure of the first layer.",[19],"Other: Placebo",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Platelet Rich Plasma","Injection of 5cc of PRP preparation at the myometrium around the uterine incision after it has been sutured.",[9],null,{"type":6,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Injection of 5cc of 0.9% Normal Saline at the myometrium around the uterine incision after it has been sutured.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Aya A Mohr-Sasson, M.D","CONTACT","3462704682","mohraya@gmail.com",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Sheba Medical Center","RECRUITING","Ramat Gan","Center","55030","Israel","IL",{"type":45,"coordinates":46},"Point",[47,48],34.81065,32.08227,{"lat":48,"lon":47},[51,55,58],{"name":52,"role":32,"phone":53,"phoneExt":25,"email":54},"Jigal Haas, MD","972-3-5302777","jigal.Haas@Sheba.health.gov.il",{"name":56,"role":32,"phone":57,"phoneExt":25,"email":34},"Aya Mohr-Sasson, MD","1-346-270-4682",{"name":52,"role":59,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"type":59,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Aya Mohr Sasson","Principle investigator",[64],{"name":37,"class":65},"OTHER_GOV","100456525","platelet-rich-plasma-for-uterine-scar-100456525",false,"NCT05224726","Platelet Rich Plasma for Uterine Scar","Platelet Rich Plasma for the Treatment of Uterine Scar","AA-PRP","Inclusion criteria:\n\n* Women undergoing elective cesarean delivery\n* Term pregnancy (≥37 weeks of gestation)\n\nExclusion criteria:\n\n* Thrombocytopenia (CBC Platelet count \\\u003C70,000)\n* Connective tissue disease\n* Uterine scars other than cesarean (s\u002Fp myomectomy, s\u002Fp cornual resection)\n* Malformed uterus (unicornuate, bicornuate, didelphic)",true,"FEMALE","18 Years","52 Years",{"count":79,"type":80},40,"ESTIMATED","INTERVENTIONAL",[83],"NA","When vessel wall injury occurs, platelets become activated, releasing more than 30 bioactive proteins, many of which have a fundamental role in hemostasis, inflammation and ultimate wound healing. Platelet-rich plasma (PRP), a modification of fibrin glue made from autologous blood, is being used to deliver growth factors in high concentration to sites requiring wound healing. PRP is obtained from a sample of patients' blood drawn at the time of treatment. As the rate of cesarean deliveries has been rising, long-term adverse sequelae due to uterine scar defects have been increasing. PRP might be a simple preventive treatment that potentially can reduce morbidity following cesarean deliveries.",[86,87,88,89],"Cesarean Section Complications","Uterine Bleeding","Pelvic Pain","Menstrual Irregularity",[91,92,93,94,95,96,97,98],"uterine scar defect","cesarean delivery","pelvic pain","spotting","niche","cesarean section complication","uterine scar","Platelet Rich Plasma (PRP)","2025-08-24",{"date":101,"type":102},"2025-08-26","ACTUAL",{"date":104,"type":102},"2025-07-19",{"date":106,"type":80},"2028-07-01",{"name":5,"class":6},1]