[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623702":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":34,"locations":40,"responsibleParty":58,"collaborators":10,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":10,"enrollmentInfo":70,"targetDuration":10,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":84,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Mersin University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PLDD Alone",null,"Patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD) as part of standard clinical care without adjunct epidural steroid injection.",[13],"Procedure: Percutaneous Laser Disc Decompression (PLDD)",{"label":15,"type":10,"description":16,"interventionNames":17},"PLDD Plus Transforaminal Epidural Steroid Injection","Patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD) followed by adjunct transforaminal anterior epidural steroid injection with dexamethasone during the same session as part of standard clinical care.",[18],"Procedure: Transforaminal Anterior Epidural Steroid Injection",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"PROCEDURE","Percutaneous Laser Disc Decompression (PLDD)","Routine minimally invasive laser-based disc decompression performed under fluoroscopic guidance to reduce intradiscal pressure in patients with lumbar disc herniation.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"Transforaminal Anterior Epidural Steroid Injection","Routine transforaminal anterior epidural injection of dexamethasone performed under fluoroscopic guidance following PLDD during the same session without additional puncture.",[15],[30],{"name":31,"affiliation":32,"role":33},"Mesut Bakır","Mersin University Faculty of Medicine, Pain Clinic","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":10,"email":39},"Mesut Bakır, Assoc.Prof","CONTACT","+905457450655","mesutbakir@gmail.com",[41],{"facility":42,"status":10,"city":43,"state":44,"zip":45,"country":46,"countryCode":10,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Mersin University Faculty of Medicine, Department of Algology","Mersin","Yenişehir","33130","Turkey (Türkiye)",{"type":48,"coordinates":49},"Point",[50,51],34.63886,36.81196,{"lat":51,"lon":50},[54],{"name":55,"role":37,"phone":56,"phoneExt":10,"email":57},"Mesut Bakır, Assoc. Prof.","+90 545 745 06 55","mesutbakir@mersin.edu.tr",{"type":33,"investigatorFullName":31,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Associate Professor of Anesthesiology and Algology","100623702","pldd-with-or-without-transforaminal-epidural-steroid-injection-in-lumbar-disc-herniation-100623702",false,"NCT07400068","PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation","Effect of Adjunct Transforaminal Anterior Epidural Steroid Injection Following Percutaneous Laser Disc Decompression in Patients With Single-Level Lumbar Disc Herniation: A Prospective Observational Study","PLDD-TFESI","Inclusion Criteria:\n\nAge 18 years and older\n\nDiagnosis of single-level lumbar disc herniation confirmed by magnetic resonance imaging (MRI)\n\nPresence of radicular leg pain refractory to conservative treatment\n\nUndergoing routine percutaneous laser disc decompression (PLDD) as part of standard clinical care\n\nAbility to provide informed consent\n\nExclusion Criteria:\n\nMultilevel lumbar disc herniation\n\nExtruded or sequestered disc herniation\n\nSevere spinal canal stenosis or spinal instability\n\nPrevious lumbar spine surgery at the affected level\n\nActive infection or systemic inflammatory disease\n\nCoagulopathy or use of anticoagulant therapy contraindicating intervention\n\nPregnancy\n\nInability to complete follow-up assessments","ALL","18 Years",{"count":71,"type":72},88,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate the clinical outcomes of patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD).\n\nIn routine clinical practice, some patients receive an additional transforaminal anterior epidural steroid injection during the same session without an extra puncture. This study will prospectively follow patients who receive PLDD alone and those who receive PLDD combined with epidural steroid injection.\n\nPain intensity, functional status, analgesic use, need for additional interventions, and complications will be assessed over time. The results may help to clarify whether adding epidural steroid injection to PLDD improves clinical outcomes in patients with lumbar disc herniation.",[76,77],"Lumbar Disc Herniation","Lumbar Radiculopathy",[79,80,81,82,83],"Percutaneous Laser Disc Decompression","Transforaminal Epidural Steroid Injection","Minimally Invasive Spine Treatment","Radicular Pain","PLDD","NOT_YET_RECRUITING","2026-02-03",{"date":87,"type":88},"2026-02-10","ACTUAL",{"date":90,"type":72},"2026-03-01",{"date":92,"type":72},"2027-09-01",{"name":5,"class":6},1]