[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594699":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":45,"collaborators":48,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":74,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"First Affiliated Hospital of Wannan Medical College","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Maintenance Hemodialysis Patients",null,"Adult patients aged 18 to 80 years who have been receiving maintenance hemodialysis for more than 3 months. All participants will be monitored for blood pressure and Pleth Variability Index (PVI) measurements before and during hemodialysis sessions. The occurrence of intradialytic hypotension and its association with PVI will be evaluated.",[13],"Other: Non-invasive Monitoring",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Non-invasive Monitoring","All participants will undergo non-invasive measurement of Pleth Variability Index (PVI) and routine blood pressure monitoring before and during hemodialysis sessions. No treatment or experimental intervention will be applied.",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Qiancheng Xu","CONTACT","86-18297529106","qianchengxu@wnmc.edu.cn",[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)","RECRUITING","Wuhu","Anhui","241000","China","CN",{"type":35,"coordinates":36},"Point",[37,38],118.42947,31.35259,{"lat":38,"lon":37},[41],{"name":42,"role":22,"phone":43,"phoneExt":10,"email":44},"Shengsheng Tao","86-18315329399","taoshengsheng@yjsyy.com",{"type":46,"investigatorFullName":21,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Principal Investigator",[49,51],{"name":50,"class":6},"Wuhu City Second People's Hospital",{"name":52,"class":6},"Wuhu County Traditional Chinese Medicine Hospital","100594699","pleth-variability-index-for-predicting-low-blood-pressure-during-maintenance-hemodialysis-100594699",false,"NCT07022847","Pleth Variability Index for Predicting Low Blood Pressure During Maintenance Hemodialysis","The Value of Pleth Variability Index in Predicting Hypotension During Maintenance Hemodialysis: A Prospective Observational Multicenter Study","PVI-HD","Inclusion Criteria:\n\n* Adults aged 18 to 80 years.\n* Diagnosis of end-stage renal disease and undergoing maintenance hemodialysis for more than 3 months.\n* Able and willing to provide informed consent and comply with study procedures.\n\nExclusion Criteria:\n\n* Severe cardiac arrhythmias or significant peripheral vascular disease that may interfere with PVI measurements.\n* Local edema, skin lesions, or other conditions that prevent accurate PVI monitoring.\n* History of hemodynamic instability unrelated to dialysis.\n* Pregnant or breastfeeding women.\n* Known allergy or contraindication to materials used in the hemodialysis circuit.\n* Unable to cooperate with study procedures.\n* Participation in another interventional clinical study within the past 30 days.","ALL","18 Years","80 Years",{"count":65,"type":66},200,"ESTIMATED","OBSERVATIONAL","What is this study about? We are studying whether the Pleth Variability Index (PVI)-a simple, non-invasive measurement from a pulse oximeter-can help predict low blood pressure (hypotension) during routine maintenance hemodialysis. Low blood pressure during dialysis is a common and potentially serious complication. Our goal is to find out if monitoring PVI can help identify patients at risk, so that early action can be taken.\n\nWho can join? Adults aged 18 to 80 years. Patients who have been receiving maintenance hemodialysis regularly for more than 3 months.\n\nThose who are willing and able to participate and sign an informed consent form.\n\nWho cannot join? Patients with severe heart rhythm problems, severe peripheral circulation problems, or swelling that makes PVI measurement unreliable.\n\nPatients who are pregnant or breastfeeding. Patients allergic to the dialysis filter or unable to cooperate with the study procedures.\n\nWhat will happen during the study? PVI Measurement: Your PVI will be checked with a simple fingertip device before starting dialysis and again 30 minutes after dialysis begins.\n\nBlood Pressure Monitoring: Your blood pressure will be closely watched throughout the dialysis session.\n\nData Collection: Information about your age, medical history, medications, lab results, dialysis settings, and other standard measurements will be recorded.\n\nWhat are the benefits and risks? Benefits: By identifying patients at higher risk for low blood pressure during dialysis, the study may lead to safer and more comfortable dialysis treatment in the future.\n\nRisks: All measurements used in this study are safe and non-invasive, with no extra risk compared to routine care.\n\nYour Rights and Safety Participation is completely voluntary-you may leave the study at any time without affecting your medical care.\n\nThe study has been reviewed and approved by the hospital's ethics committee. Your privacy and personal data will be strictly protected.",[70,71,72,73],"Hypotension and Shock","Hemodialysis","End-Stage Renal Disease Requiring Haemodialysis","Intradialytic Hypotension",[75,71,73,76,77,16,78,79],"Pleth Variability Index","Blood Pressure Monitoring","End-Stage Renal Disease","Predictive Marker","Maintenance Dialysis","2025-06-07",{"date":82,"type":83},"2025-06-15","ACTUAL",{"date":85,"type":83},"2025-02-01",{"date":87,"type":66},"2025-06-30",{"name":5,"class":6},1]