[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569189":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":35,"locations":41,"responsibleParty":57,"collaborators":25,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":25,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":25,"overallStatus":80,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1 (Mechanical pleurodesis)","EXPERIMENTAL","Pleural abrasions will be done by scrubbing the parietal and visceral pleura until a uniform aspect of bloody pleura by a piece of gauze attached to the end of a holding forceps, and intercostal tube will then placed and monitoring of lung expansion will be done through serial CXR and chest ultrasound follow up and when the lung is fully expanded the tube will be clamped for two hours and follow up CXR will be done for follow up and then the tube removed.",[13],"Procedure: Group 1 (mechanical pleurodesis)",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2 (Chemical pleurodesis by bleomycin)","Those Patients will have indwelling pleural catheter through which pleural fluid will be drained until dryness and then pleurodesis will be done by 60 mg bleomycin dissolved in 50 ml 0.9% saline and 10 ml 2% xylocaine solution then the catheter will be clamped for 6 hours.",[18],"Procedure: Group 2 chemical pleurodesis by bleomycin)",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Group 1 (mechanical pleurodesis)","pleural abrasions will be done by scrubbing the parietal and visceral pleura until a uniform aspect of bloody pleura by a piece of gauze attached to the end of a holding forceps , intercostal tube will then placed and monitoring of lung expansion will be done through serial CXR and chest ultrasound follow up and when the lung is fully expanded the tube will be clamped for two hours and follow up CXR will be done for follow up and then the tube removed",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Group 2 chemical pleurodesis by bleomycin)","Those Patients will have indwelling pleural catheter through which pleural fluid will be drained until dryness and then pleurodesis will be done by 60 mg bleomycin dissolved in 50 ml 0.9% saline and 10 ml 2% xylocaine solution then the catheter will be clamped for 6 hours",[15],[31],{"name":32,"affiliation":33,"role":34},"Mohamed M Abd ElHady, Professor","Assiut University Faculty of Medicine","STUDY_DIRECTOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Montaser G Zahran, Professor","CONTACT","+201008951058","montaser_zahran@yahoo.com",[42],{"facility":33,"status":25,"city":43,"state":25,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Asyut","71515","Egypt","EG",{"type":48,"coordinates":49},"Point",[50,51],31.18368,27.18096,{"lat":51,"lon":50},[54],{"name":37,"role":38,"phone":55,"phoneExt":56,"email":40},"01008951058","002",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Asmaa Mahmoud Mohammed Eltayeb","Assistant lecturer of chest diseases","100569189","pleural-bleomycin-vs-mechanical-abrasion-in-malignant-pleural-effusion-100569189",false,"NCT06691009","Pleural Bleomycin vs Mechanical Abrasion in Malignant Pleural Effusion","Effectiveness of Pleurodesis by Pleural Abrasion Using Medical Thoracoscopy Versus Bleomycin Via Pleural Catheter in Patients With Malignant Pleural Effusion","Inclusion Criteria:\n\n* Patients who are 18 years old or more.\n* patients with rapidly accumulating moderate \\& massive malignant pleural. effusion that need frequent aspiration to relieve dyspnea and affect quality of life of the patient.\n\nExclusion Criteria:\n\n* patients not fit for thoracoscoy.\n* patients with life expectency less than 1 month .\n* trapped lung (endobronchial lesion).\n* excessive pleural adhesios.\n* mild effusion not need frequent aspiration and not affect\n* quality of life .\n* patients with chest infection : pneumonia , empyema .\n* patients with performance status that doesn't expected to increase by 1","ALL","18 Years","80 Years",{"count":72,"type":73},70,"ESTIMATED","INTERVENTIONAL",[76],"NA","Comparision between pleurodesis by pleural abrasion using medical thoracoscopy and bleomycin instillation via indwelling pleural catheter. Evaluating the effectiveness of pleural abrasion using medical thoracoscopy in patients with malignant pleural effusion and evaluating the role of ROSE in diagnosis and management of malignant pleural effusion",[79],"Malignant Pleural Effusion","NOT_YET_RECRUITING","2024-11-13",{"date":83,"type":84},"2024-11-15","ACTUAL",{"date":86,"type":73},"2024-12-10",{"date":88,"type":73},"2029-10-10",{"name":5,"class":6},1]