[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638679":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":22,"locations":11,"responsibleParty":32,"collaborators":35,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":11,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":11,"enrollmentInfo":78,"targetDuration":11,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":11,"overallStatus":87,"whyStopped":11,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":11},{"fullName":5,"class":6},"Changhai Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Polyp Pretreatment Device","EXPERIMENTAL",null,[13],"Device: Polyp Pretreatment Device",{"label":15,"type":16,"description":11,"interventionNames":11},"Standard Processing","NO_INTERVENTION",[18],{"type":19,"name":9,"description":20,"armGroupLabels":21,"otherNames":11},"DEVICE","This novel polyp pretreatment device is a single-use, non-invasive laboratory tool designed to standardize the orientation and fixation of resected colorectal polyp specimens. The device consists of a flat, rigid base with a transparent, non-adherent cover, and is engineered to maintain the mucosal surface of the polyp specimen flat and fully extended.",[9],[23,28],{"name":24,"role":25,"phone":26,"phoneExt":11,"email":27},"Zhaoshen Li","CONTACT","86-021-31161365","li.zhaoshen@hotmail.com",{"name":29,"role":25,"phone":30,"phoneExt":11,"email":31},"Yu Bai","86-021-31161335","baiyu1998@hotmail.com",{"type":33,"investigatorFullName":24,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","MD,Director, Department of Gastroenterology and Digestive Endoscopy Center, Principal Investigator",[36,38,40,43,45,47,49,51,53,56,58,60,62,64,66],{"name":37,"class":6},"Heilongjiang Provicial Hospital",{"name":39,"class":6},"Ankang Central Hospital",{"name":41,"class":42},"Huadong Hospital Affiliated with Fudan University, Shanghai","UNKNOWN",{"name":44,"class":6},"The First Affiliated Hospital of Nanchang University",{"name":46,"class":42},"Ya'an People's Hospital",{"name":48,"class":6},"The Second Hospital of Hebei Medical University",{"name":50,"class":6},"Chongqing General Hospital",{"name":52,"class":42},"Guangzhou Medical University Affiliated Qingyuan Hospital (Qingyuan People's Hospital)",{"name":54,"class":55},"Shanxi Provincial People's Hospital","OTHER_GOV",{"name":57,"class":42},"Shanghai Sixth Hospital",{"name":59,"class":42},"People's Hospital of Leshan, Sichuan Province",{"name":61,"class":6},"The Third People's Hospital of Chengdu",{"name":63,"class":42},"The Third People's Hospital of Jingdezhen",{"name":65,"class":42},"Ningbo Hospital of Integrated Traditional Chinese and Western Medicine",{"name":67,"class":42},"Shandong Provincial Second People's Hospital","100638679","polyp-pretreatment-device-for-ssl-diagnosis-100638679",false,"NCT07601230","Polyp Pretreatment Device for SSL Diagnosis","Efficacy of a Polyp Pretreatment Device in Improving Diagnosis of Sessile Serrated Lesions in Colorectal Polyps","Inclusion Criteria:\n\n1. Patients undergoing colonoscopic polypectomy (≤3 lesions if multiple).\n2. Sessile\u002Fflat polyps (Paris 0-Is,0-IIa, 0-IIb, 0-IIc) resected by snare or EMR with intact specimens.\n3. Signed informed consent.\n\nExclusion Criteria:\n\n1. Refusal or lack of informed consent.\n2. Polyp size ≥25 mm or fragmented resection.\n3. Severe specimen damage\u002Fcautery artifact or time from resection to fixation \\>30 min.\n4. Suspected\u002Fconfirmed CRC, IBD, or polyposis syndromes.\n5. Anticoagulants (aspirin\u002Fwarfarin) within 7 days or coagulation disorders.",true,"ALL","18 Years",{"count":79,"type":80},1156,"ESTIMATED","INTERVENTIONAL",[83],"NA","Colorectal cancer (CRC) is the third most common malignancy globally. Sessile serrated lesions (SSLs) account for 15-30% of CRC via the serrated pathway. Accurate SSL diagnosis relies on basal crypt features, which are often obscured by specimen curling during standard formalin fixation, leading to underdiagnosis. A novel polyp pretreatment device mechanically maintains mucosal flatness, ensuring vertical sectioning relative to the muscularis mucosae. This randomized, double-blind, parallel-controlled trial evaluates whether the device improves SSL diagnostic rate and section orientation in sessile colorectal polyps.",[86],"Sessile Serrated Lesion","NOT_YET_RECRUITING","2026-05-17",{"date":90,"type":91},"2026-05-22","ACTUAL",{"date":93,"type":80},"2026-06-15",{"date":95,"type":80},"2028-05-01",{"name":5,"class":6}]