[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601303":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":57,"collaborators":26,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":26,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":80,"overallStatus":84,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Tanta University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"group 1: zinc oxide-pomegranate peel extract paste","EXPERIMENTAL","30 primary molars will be treated with pomegranate peel extract freshly mixed with zinc oxide powder till it reaches a suitable consistency (1:1 ratio by volume) to cover pulp stumps",[13,14],"Procedure: Pulpotomy","Procedure: Radiation",{"label":16,"type":17,"description":18,"interventionNames":19},"group 2: MTA","ACTIVE_COMPARATOR","30 primary molars will be treated with MTA to cover pulp stumps",[13,14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Pulpotomy","Teeth will be anesthetized then Rubber dam and high suction will be used in pulpotomy procedure. Cavity outline will be performed by sterile #330 high speed bur using water spray. Caries will be removed by large spoon excavator. When pulpal exposure occurred, the roof of pulp chamber will be removed by low speed round bur. Haemostasis will be obtained by applying pressure with a moist cotton pellet with saline. Then the test materials will be applied. after that, pulp stumps of all molars in each group will be dressed using Intermediate restorative material, then the tooth will be restored with a preformed stainless steel crown",[9,16],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Radiation","Radiographic evaluation will be performed immediately after teeth restoration (baseline radiograph), then after three, six, and twelve months for the furcation radiolucency area and bone radiodensity. A photo-simulated phosphorus plate sensor was used to take direct standardized digital radiographs. The parallel periapical technique was obtained by Rinn, which is attached to the X-ray tube with its arm fastened to the film holder that contained a coated PSP (photo-stimulated phosphorus plate). To ensure standardization during radiographic film retakes, condensation rubber base impression material will be positioned on the outside of the film holder, and the child is told to bite on it while the material is set. The sensor wil exposed to an X-ray machine (Planmeca ProX, Helsinki, Finland) with a central ray perpendicular to the sensor at 70 kVp, 6 mA, and 0.8 s. Radio-densitometric and radiometric analysis of the radiographs will be performed by RadiAnt software.",[9,16],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"shaimaa eldesouky, assistant professor","CONTACT","+201008994242","shaimaaeldesouky@dent.tanta.edu.eg",[38],{"facility":5,"status":26,"city":39,"state":26,"zip":26,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Tanta","Egypt","EG",{"type":43,"coordinates":44},"Point",[45,46],31.00192,30.78847,{"lat":46,"lon":45},[49,51,54],{"name":33,"role":34,"phone":50,"phoneExt":26,"email":36},"01008994242",{"name":52,"role":53,"phone":26,"phoneExt":26,"email":26},"Shimaa Hadwa, assistant professor","PRINCIPAL_INVESTIGATOR",{"name":55,"role":56,"phone":26,"phoneExt":26,"email":26},"Nora Abo Shanady, lecturer","SUB_INVESTIGATOR",{"type":53,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Shaimaa Shaban Mohamed El-desouky","associate professor of pediatric dentistry, faculty of dentistry, Tanta university","100601303","pomegranate-peel-extract-for-primary-molar-pulpotomy-100601303",false,"NCT07108738","Pomegranate Peel Extract for Primary Molar Pulpotomy","Exploring Natural Alternatives: Pomegranate Peel Extract for Primary Molar Pulpotomy","Inclusion Criteria:\n\n* Restorable primary molars with deep carious lesions.\n* Absence of gingival swelling or sinus tract.\n* Absence of spontaneous pain\n* Absence of pain on percussion.\n* Absence of discontinuity of lamina dura\n* Absence of internal root resorption.\n* Absence of external root resorption.\n* Absence of inter-radicular or periapical bone destruction (radiolucency).\n\nExclusion Criteria:\n\n* presence of spontaneous pain\n* presence of gingival swelling or sinus tract\n* presence of internal or external root resorption\n* pain on percussion.","ALL","4 Years","7 Years",{"count":71,"type":72},30,"ESTIMATED","INTERVENTIONAL",[75],"NA","Pomegranate peel extract has demonstrated a range of potential uses in the biomedical industry in recent years because of its numerous benefits, which include anti-inflammatory, antibacterial, anti-apoptotic, antioxidant, and cell-regeneration-promoting qualities. Therefore, the purpose of this study will be to evaluate the clinical and radiographic efficacy of Pomegranate peel extract as a pulpotomy agent in primary teeth.",[78,79],"Pulpitis Reversible","Pulp Exposure, Dental",[23,81,82,83],"Primary molars","Pomegranate Peel Extract","Mineral Trioxide Aggregate","NOT_YET_RECRUITING","2025-07-31",{"date":87,"type":88},"2025-08-07","ACTUAL",{"date":90,"type":72},"2025-08",{"date":92,"type":72},"2026-04",{"name":5,"class":6},1]