[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613847":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":26,"centralContacts":34,"locations":42,"responsibleParty":58,"collaborators":20,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":20,"enrollmentInfo":71,"targetDuration":20,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":87,"whyStopped":20,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Ospedale Santa Croce-Carle Cuneo","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Enrolled patients with FIGO 2018 IA-IB epithelial or non-epithelial ovarian\u002Ffallopian tube neoplasma","All patients will receive standard pre-, intra-, and postoperative care according to institutional guidelines. The peritonectomy procedure will not alter the choice of surgical access. Pelvic peritonectomy specimens will be analyzed as part of the final pathology report.",[12,13],"Procedure: systematic surgical approach to wider peritoneal biopsies according with dissection of retroperitoneal spaces, nerve-sparing approach","Diagnostic Test: Histopathologic Analysis",[15,21],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","systematic surgical approach to wider peritoneal biopsies according with dissection of retroperitoneal spaces, nerve-sparing approach","Surgical Procedure:\n\nInitial step: Exclude upper abdominal disease through inspection and guideline-based biopsies.\n\nPelvic peritoneal resection: En bloc or segmental removal of predefined pelvic peritoneal regions according to dissection of retroperitoneal spaces with a nerve-sparing technique.",[9],null,{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":20},"DIAGNOSTIC_TEST","Histopathologic Analysis","Fixation: 10% neutral-buffered formalin for 6-48 hours. Processing: Paraffin eembedding and complete sampling for histology. Staining: H\\&E and immunohistochemistry (MOC-31, BER-EP4) to identify epithelial tumor cells. Reporting: Checklist for peritoneal disease",[9],[27,31],{"name":28,"affiliation":29,"role":30},"Andrea Puppo, MD","Azienda Ospedaliera Santa Croce e Carle Cuneo","PRINCIPAL_INVESTIGATOR",{"name":32,"affiliation":29,"role":33},"Elena Olearo, MD","STUDY_DIRECTOR",[35,39],{"name":28,"role":36,"phone":37,"phoneExt":20,"email":38},"CONTACT","00390171642867","puppo.a@ospedale.cuneo.it",{"name":32,"role":36,"phone":40,"phoneExt":20,"email":41},"00390171642369","eolearo@gmail.com",[43],{"facility":29,"status":20,"city":44,"state":20,"zip":20,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Cuneo","Italy","IT",{"type":48,"coordinates":49},"Point",[50,51],7.54828,44.39071,{"lat":51,"lon":50},[54],{"name":55,"role":36,"phone":56,"phoneExt":20,"email":57},"Silvia Violante, MD","00390171641539","violante.s@ospedale.cuneo.it",{"type":30,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Elena Olearo","MD","100613847","ponder-pelvic-peritonectomy-in-early-stage-ovarian-tumors-100613847",false,"NCT07271914","PONDER: Pelvic Peritonectomy in Early Stage Ovarian Tumors","Pelvic peritOnectomy iN Early Stage Ovarian Tumors: a prospEctive Study","PONDER","Inclusion Criteria:\n\n* Age ≥ 18 years\n* FIGO 2018 stage IA-IB epithelial or non-epithelial ovarian or fallopian tube tumors\n* Complete preoperative work-up (ultrasound, CT scan, tumor markers)\n* Laparoscopic, robotic or open surgical approach\n* Signed informed consent\n\nExclusion Criteria:\n\n* Sarcomas, melanomas, mesotheliomas, hematologic malignancies\n* Advanced ovarian tumors\n* Fertility-sparing surgery with uterine preservation\n* Inability to provide informed consent","FEMALE","18 Years",{"count":72,"type":73},390,"ESTIMATED","INTERVENTIONAL",[76],"NA","Early-stage ovarian tumors represent approximately 30% of all newly diagnosed ovarian cancers. Current international guidelines recommend random peritoneal biopsies for surgical staging, but the diagnostic yield of these biopsies remains limited. The PONDER study aims to evaluate whether standardized surgical procedure and pathology assessment of wider peritoneal pelvic biopsies can increase the detection rate of microscopic peritoneal implants and micrometastases in patients with early-stage ovarian tumors. This multicenter, prospective, single-arm study includes both minimally invasive and open surgical approaches, with a standardized gross and microscopic evaluation of the resected peritoneal specimens",[79,80],"Early Stage Ovarian Tumors","Peritoneal Carcinosis",[82,83,84,85,86],"ovarian cancer","early stage","ovarian tumor","peritoneal carcinosis","pathology assessment","NOT_YET_RECRUITING","2025-11-26",{"date":90,"type":91},"2025-12-09","ACTUAL",{"date":93,"type":73},"2026-02",{"date":95,"type":73},"2032-08",{"name":5,"class":6},1]