[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634082":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":27,"centralContacts":35,"locations":42,"responsibleParty":65,"collaborators":47,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":77,"minAge":78,"maxAge":47,"enrollmentInfo":79,"targetDuration":47,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":91,"overallStatus":45,"whyStopped":47,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CTG with Existing Fixed Partial Denture","EXPERIMENTAL","Participants with pontic site defects associated with an existing fixed partial denture (FDP) will receive soft tissue augmentation using a connective tissue graft (CTG) without removal of the prosthesis.",[13],"Procedure: Connective Tissue Graft (CTG)",{"label":15,"type":10,"description":16,"interventionNames":17},"CTG without Fixed Partial Denture","Participants with pontic site defects without an existing fixed partial denture will receive soft tissue augmentation using a connective tissue graft (CTG). A temporary bridge will be provided during healing.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Connective Tissue Graft (CTG)","Soft tissue augmentation will be performed using a subepithelial connective tissue graft (CTG) harvested from the palate and placed at the pontic site using a minimally invasive pouch\u002Ftunnel technique. The procedure aims to increase soft tissue thickness and improve contour in edentulous ridge defects. The same surgical protocol will be applied in all participants, with variation based only on the presence or absence of an existing fixed partial denture.",[9,15],[25,26],"Subepithelial Connective Tissue Graft","Soft Tissue Augmentation",[28,32],{"name":29,"affiliation":30,"role":31},"Enji Ahmed Mahmoud, PHD holder","Professor of Oral Medicine and Periodontology - Faculty of Dentistry, Cairo University.","STUDY_DIRECTOR",{"name":33,"affiliation":34,"role":31},"Omnia Khaled Tawfik, PHD Holder","Lecturer of Oral Medicine and Periodontology- Cairo University.",[36],{"name":37,"role":38,"phone":39,"phoneExt":40,"email":41},"Ahmed Mohamed Elatreby, BDs","CONTACT","01004177718","+2","ahmed.elatreby@dentistry.cu.edu.eg",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Faculty of Dentistry, Cairo University","RECRUITING","Cairo",null,"12613","Egypt","EG",{"type":52,"coordinates":53},"Point",[54,55],31.24967,30.06263,{"lat":55,"lon":54},[58,62],{"name":59,"role":38,"phone":60,"phoneExt":47,"email":61},"Faculty of Dentistry Cairo University","010 02159535","dentmail@dentistry.cu.edu.eg",{"name":63,"role":64,"phone":47,"phoneExt":47,"email":47},"Ahmed Mohamed Elatreby, BDS","PRINCIPAL_INVESTIGATOR",{"type":64,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":47,"oldOrganization":47},"Ahmed Mohamed Hassan Elatreby","Master's student, Department of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University","100634082","pontic-site-development-with-or-without-fixed-partial-denture-100634082",false,"NCT07535060","Pontic Site Development With or Without Fixed Partial Denture","Clinical and Volumetric Evaluation of Soft Tissue Augmentation Using Connective Tissue Graft (CTG) in Pontic Site Defects With and Without Fixed Partial Dentures. A Non-randomized Clinical Trial.","Pontic Site","Inclusion Criteria:\n\n* Patients will on missing tooth in the esthetic zone (2nd premolar to 2nd premolar), missing at least 3 months prior to recruitment, with or without FPD\n* Systemically free patient\n* ≥18 years of age\n* Intact gingival tissue with at least 2mm keratinized tissue in adjacent teeth\n* Patients accept to provide informed consent\n\nExclusion Criteria:\n\n* Smokers.\n* Pregnancy and lactation\n* Periodontitis\n* Severe gagging reflex\n* Handicapped and mentally challenged patients\n* Active soft tissue infection",true,"ALL","18 Years",{"count":80,"type":81},20,"ESTIMATED","INTERVENTIONAL",[84],"NA","This study aims to evaluate the effectiveness of soft tissue augmentation using connective tissue graft (CTG) in pontic site defects. It compares clinical and volumetric outcomes between sites with an existing fixed partial denture (FDP) and sites without an FDP.\n\nFollowing tooth extraction, alveolar ridge resorption often leads to soft tissue defects that can compromise esthetics, function, and prosthetic outcomes. CTG is considered the gold standard for soft tissue augmentation due to its predictable improvement in tissue thickness and stability.\n\nIn this non-randomized clinical trial, patients with single edentulous sites in the esthetic zone will undergo CTG using a standardized surgical technique. The primary outcome is keratinized tissue thickness, while secondary outcomes include keratinized tissue width, volumetric soft tissue changes, esthetic evaluation (Pink Esthetic Score), plaque index, post-operative pain, and patient satisfaction.\n\nClinical and digital assessments will be conducted preoperatively and at follow-up intervals up to 6 months. The study aims to determine whether performing CTG around an existing bridge provides comparable or improved outcomes compared to sites without a bridge, potentially offering a less invasive alternative to prosthetic replacement.",[87,88,89,90],"Mucogingival Defects","Pontic Site Development","Keratinized Tissue Deficiency","Connective Tissue Graft",[21,26,88,92,93,94,95,96,97,98,99,100,101,102,103],"Alveolar Ridge Defects","Fixed Partial Denture (FDP)","Ridge Augmentation","Periodontal Plastic Surgery","Keratinized Tissue Thickness","Keratinized Tissue Width","Esthetic Outcome","Pink Esthetic Score (PES)","Volumetric Soft Tissue Analysis","Dental Prosthetics","Edentulous Ridge","Non-Randomized Clinical Trial","2026-04-27",{"date":106,"type":107},"2026-05-01","ACTUAL",{"date":109,"type":107},"2025-10-06",{"date":111,"type":81},"2027-06-01",{"name":5,"class":6},1]