[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541305":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":37,"responsibleParty":84,"collaborators":87,"id":94,"slug":95,"hasResults":96,"nctId":97,"briefTitle":98,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":96,"sex":101,"minAge":102,"maxAge":18,"enrollmentInfo":103,"targetDuration":18,"studyType":106,"phases":107,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":40,"whyStopped":18,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":124},{"fullName":5,"class":6},"Brigham and Women's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Positive Affect in the Transplantation of Hematopoietic Stem Cells (PATH)","EXPERIMENTAL","Participants recruited from the Dana-Farber Cancer Institute, Duke Cancer Institute, and Moffitt Cancer Center who are randomized to the intervention\u002Fexperimental arm will receive the PATH intervention, which is focused on gratitude, strengths, and meaning, as well as focused exercises on goal-setting and tracking daily physical activity.\n\nParticipants will complete questionnaires (in person, over the computer or telephone, or by mail) at predetermined days per protocol.",[13],"Behavioral: PATH",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care","NO_INTERVENTION","Participants recruited from the Dana-Farber Cancer Institute, Duke Cancer Institute, and Moffitt Cancer Center who are randomized to the usual care arm will receive their usual support from the HSCT team, including all routine supportive care resources (e.g., support from social work) offered by the HSCT team.\n\nParticipants will complete questionnaires (in person, over the computer or telephone, or by mail) at predetermined days per protocol.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","PATH","PATH, a phone-delivered positive psychology intervention for patients who have undergone HSCT, consists of three 3-week modules. The first module focuses on gratitude and physical activity goal setting. The second module focuses on personal strengths and resources to enhance daily physical activity. The third module focuses on meaning and assessing barriers to physical activity. The third week of each module is an integration exercise dedicated to help participants explore practical ways of incorporating the themes for the given module into daily life. A trained interventionist will guide participants to complete each 30-minute weekly session.",[9],[26],{"name":27,"affiliation":5,"role":28},"Hermioni Amonoo, MD, MPP, MPH","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":33},"CONTACT","617-525-7472","hermioni_amonoo@dfci.harvard.edu",{"name":35,"role":31,"phone":18,"phoneExt":18,"email":36},"Isabella Larizza, BSc","ilarizza@bwh.harvard.edu",[38,56,70],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Moffitt Cancer Center","RECRUITING","Tampa","Florida","33612","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-82.45843,27.94752,{"lat":50,"lon":49},[53],{"name":54,"role":31,"phone":18,"phoneExt":18,"email":55},"Heather Jim, PhD","heather.jim@moffitt.org",{"facility":57,"status":40,"city":58,"state":59,"zip":60,"country":44,"countryCode":45,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Dana Farber Cancer Institute","Boston","Massachusetts","02215",{"type":47,"coordinates":62},[63,64],-71.05977,42.35843,{"lat":64,"lon":63},[67,69],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":68},"Hermioni_Amonoo@dfci.harvard.edu",{"name":27,"role":28,"phone":18,"phoneExt":18,"email":18},{"facility":71,"status":40,"city":72,"state":73,"zip":74,"country":44,"countryCode":45,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"Duke Cancer Institute","Durham","North Carolina","27710",{"type":47,"coordinates":76},[77,78],-78.89862,35.99403,{"lat":78,"lon":77},[81],{"name":82,"role":31,"phone":18,"phoneExt":18,"email":83},"Thomas LeBlanc, MD","thomas.leblanc@duke.edu",{"type":28,"investigatorFullName":85,"investigatorTitle":86,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Hermioni L.Amonoo, MD, MPP, MPH","Director, Well-Being and Cancer Research Program",[88,90,92],{"name":89,"class":6},"Dana-Farber Cancer Institute",{"name":91,"class":6},"Duke University",{"name":93,"class":6},"H. Lee Moffitt Cancer Center and Research Institute","100541305","positive-psychology-intervention-for-hematopoietic-stem-cell-transplantation-survivors-100541305",false,"NCT06328127","Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors","PATH-4","Inclusion Criteria:\n\n* Adult patients (aged 18 years and older) undergoing allogeneic HSCT and are approaching 100-days post-HSCT\n* Ability to speak, read, and respond to questions in English or Spanish to complete study procedures\n* Access to a basic telephone\n\nExclusion Criteria:\n\n* Patients who underwent allogeneic HSCT for benign hematologic conditions\n* Patients with severe psychiatric or cognitive conditions, such as dementia, determined by their transplant oncologist to make them unable to provide informed consent or comply with study procedures","ALL","18 Years",{"count":104,"type":105},400,"ESTIMATED","INTERVENTIONAL",[108],"NA","This randomized clinical trial is evaluating the impact of a positive psychology intervention (PATH) on anxiety symptoms, depression symptoms, and quality of life in survivors of hematopoietic stem cell transplant (HSCT) compared to usual care.",[111],"Hematopoietic Stem Cell Transplant",[113,114],"stem cell transplant","positive psychology intervention","2025-11-11",{"date":117,"type":118},"2025-11-13","ACTUAL",{"date":120,"type":118},"2024-12-17",{"date":122,"type":105},"2030-05-31",{"name":5,"class":6},3]