[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635644":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":54,"collaborators":25,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":25,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"University of Roma La Sapienza","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group Test: microRepair ABX Mousse","EXPERIMENTAL","Patients in this group will apply a mouthwash in mousse form enriched with microRepair particles and an Antibacterial Complex (ABX). The product is designed to bind to the oral mucosa, stimulating tissue regeneration and providing antibacterial protection to the post-extraction site.",[13],"Other: microRepair ABX Mousse",{"label":15,"type":16,"description":17,"interventionNames":18},"Group Control: CHX 0.20%","ACTIVE_COMPARATOR","Patients in this group will use a standard liquid mouthwash containing 0.20% Chlorhexidine (CHX). This represents the traditional antiseptic protocol for managing oral hygiene and preventing infection in the post-operative period.",[19],"Other: CHX mouthwash 0.20%",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"microRepair ABX Mousse","Topical application of the mousse on the surgical wound starting from the day after the extraction. The mousse is specifically formulated to promote healing through microparticles that accelerate tissue repair and an antibacterial complex to prevent localized infections.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"CHX mouthwash 0.20%","Application of 0.20% Chlorhexidine liquid mouthwash. Used as a control treatment to evaluate the comparative effectiveness of the test product in reducing plaque, pain, and inflammation while promoting socket healing.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Fabrizio Guerra","CONTACT","3283150627","fabrizio.guerra@uniroma1.it",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Sapienza università di Roma","RECRUITING","Roma","RM","00161","Italy","IT",{"type":46,"coordinates":47},"Point",[48,49],11.10642,44.99364,{"lat":49,"lon":48},[52],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":53},"prof.fabrizio.guerra@gmail.com",{"type":55,"investigatorFullName":32,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Associate professor, MD, pHd","100635644","post-extraction-healing-microrepair-vs-chlorhexidine-100635644",false,"NCT07555366","Post-Extraction Healing: microRepair vs Chlorhexidine","Evaluation of Healing in Post-Extraction Sockets Using microRepair Abx Mousse Mouthwash Versus 0.20% Chlorhexidine","Inclusion Criteria:\n\nAge range: Patients between 18 and 75 years of age.\n\nIndication for tooth extraction: Specifically for cases involving:\n\n* Destructive caries that do not allow for conservative or prosthetic recovery.\n* Untreatable endodontic and\u002For periapical lesions.\n* Advanced periodontal lesions with significant loss of supporting tissue.\n* Traumatic lesions involving root fractures (vertical or at the middle third).\n* Malpositioned teeth causing functional alterations.\n* Roots that cannot be prosthetically recovered or residual roots.\n\nExclusion Criteria:\n\nAge: Patients under 18 or over 75 years of age. Systemic Conditions: Presence of immunodepression or immunocompromisation (e.g., HIV infection).\n\nPregnancy and Lactation: Women who are currently pregnant or breastfeeding. Mental Health: Presence of psychiatric disorders. Tobacco Use: Severe smokers, defined as consuming more than 10 cigarettes per day.\n\nSubstance Abuse: History of alcohol or drug abuse.","ALL","18 Years","75 Years",{"count":68,"type":69},30,"ESTIMATED","INTERVENTIONAL",[72],"NA","This randomized clinical trial evaluates the efficacy of a microRepair ABX mouthwash mousse compared to 0.20% chlorhexidine in promoting wound healing following tooth extraction. The study monitors clinical parameters such as pain, swelling, and healing indices at 1, 7, and 15 days post-surgery. The primary objective is to determine if the microRepair ABX technology enhances tissue regeneration and reduces post-operative complications.",[75,76],"Endodontic Issue","Periodontal Issues",[78,79,80],"tooth extraction","abx","chx","2026-04-23",{"date":83,"type":84},"2026-04-29","ACTUAL",{"date":86,"type":84},"2024-09-01",{"date":88,"type":69},"2027-03-01",{"name":5,"class":6},1]